Resultats de la cerca - David C. Tully
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Functional Profiling of Recombinant NS3 Proteases from All Four Serotypes of Dengue Virus Using Tetrapeptide and Octapeptide Substrate Libraries per Jun Li, Siew Pheng Lim, David Beer, Viral Patel, Daying Wen, Christine Tumanut, David C. Tully, Jennifer Williams, Jan Jiřiček, John P. Priestle, Jennifer L. Harris, Subhash G. Vasudevan
Publicat 2005Artigo -
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Chemical activation of the mechanotransduction channel Piezo1 per Ruhma Syeda, Jie Xu, Adrienne E. Dubin, Bertrand Coste, Jayanti Mathur, Truc T. Huynh, Jason Matzen, Jianmin Lao, David C. Tully, Ingo H. Engels, H. Michael Petrassi, Andrew M. Schumacher, M Montal, Michael Bandell, Ardem Patapoutian
Publicat 2015Artigo -
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Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH) per David C. Tully, Paul V. Rucker, D. CHIANELLI, Jennifer Williams, Agnès Vidal, Phil B. Alper, Daniel Mutnick, Badry Bursulaya, James Schmeits, Xiangdong Wu, Dingjiu Bao, Jocelyn Zoll, Young Kim, Todd Groessl, Peter McNamara, H. Martin Seidel, Valentina Molteni, Bo Liu, Andrew Phimister, Sean B. Joseph, Bryan Laffitte
Publicat 2017Artigo -
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Tropifexor‐Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents per Eloy D. Hernandez, Lianxing Zheng, Young Ho Kim, Bin Fang, Bo Liu, Reginald Valdez, William F. Dietrich, Paul V. Rucker, D. CHIANELLI, James Schmeits, Dingjiu Bao, Jocelyn Zoll, Claire M. Dubois, Glenn C. Federe, Lihao Chen, Sean B. Joseph, Lloyd B. Klickstein, John C. Walker, Valentina Molteni, Peter McNamara, Shelly Meeusen, David C. Tully, Michael K. Badman, Jie Xu, Bryan Laffitte
Publicat 2019Artigo -
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Imidazolopiperazines: Lead Optimization of the Second-Generation Antimalarial Agents per A. S. Nagle, Tao Wu, Kelli Kuhen, Kerstin Gagaring, Rachel Borboa, Caroline Francek, Zhong Chen, David Plouffe, Xuena Lin, Christopher Caldwell, Jared Ek, Suzanne Skolnik, Fenghua Liu, Jianling Wang, Jonathan Chang, Chun Li, Bo Liu, Thomas Hollenbeck, Tove Tuntland, John Isbell, Tiffany Chuan, Philip B. Alper, Christoph Fischli, Reto Brun, Suresh B. Lakshminarayana, Matthias Rottmann, Thierry T. Diagana, Elizabeth A. Winzeler, Richard Glynne, David C. Tully, Arnab K. Chatterjee
Publicat 2012Artigo -
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Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis per D. CHIANELLI, Paul V. Rucker, Jason Roland, David C. Tully, John T. Nelson, Xiaodong Liu, Badry Bursulaya, Eloy D. Hernandez, Jane Y. Wu, Mahavir Prashad, Thierry Schlama, Yugang Liu, Alan Chu, James Schmeits, David Huang, Robert Hill, Dingjiu Bao, Jocelyn Zoll, Young Kim, Todd Groessl, Peter McNamara, Bo Liu, Wendy Richmond, Ignacio Sancho-Martinez, Andrew Phimister, H. Martin Seidel, Michael K. Badman, Sean B. Joseph, Bryan Laffitte, Valentina Molteni
Publicat 2020Artigo -
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Imidazolopiperazines: Hit to Lead Optimization of New Antimalarial Agents per Tao Wu, A. S. Nagle, Kelli Kuhen, Kerstin Gagaring, Rachel Borboa, Caroline Francek, Zhong Chen, David Plouffe, Anne Goh, Suresh B. Lakshminarayana, Jeanette Wu, Hui Qing Ang, Peiting Zeng, Min Low Kang, William Tan, Maria Carmen S. Tan, Nicole Ye, Xuena Lin, Christopher Caldwell, Jared Ek, Suzanne Skolnik, Fenghua Liu, Jianling Wang, Jonathan Chang, Chun Li, Thomas Hollenbeck, Tove Tuntland, John Isbell, Christoph Fischli, Reto Brun, Matthias Rottmann, Véronique Dartois, Thomas H. Keller, Thierry T. Diagana, Elizabeth A. Winzeler, Richard Glynne, David C. Tully, Arnab K. Chatterjee
Publicat 2011Artigo -
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KAF156 Is an Antimalarial Clinical Candidate with Potential for Use in Prophylaxis, Treatment, and Prevention of Disease Transmission per Kelli Kuhen, Arnab K. Chatterjee, Matthias Rottmann, Kerstin Gagaring, Rachel Borboa, Jennifer Buenviaje, Zhong Chen, Carolyn Francek, Tao Wu, A. S. Nagle, S. Whitney Barnes, David Plouffe, Lee M, David A. Fidock, Wouter Graumans, Marga van de Vegte‐Bolmer, Geert Jan van Gemert, Grennady Wirjanata, Boni F. Sebayang, Jutta Marfurt, Bruce Russell, Rossarin Suwanarusk, Ric N. Price, François Nosten, Anchalee Tungtaeng, Montip Gettayacamin, Jetsumon Sattabongkot, Jennifer Taylor, John R. Walker, David C. Tully, Kailash P. Patra, Erika L. Flannery, Joseph M. Vinetz, Laurent Rénia, Robert W. Sauerwein, Elizabeth A. Winzeler, Richard Glynne, Thierry T. Diagana
Publicat 2014Artigo -
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Targeting Plasmodium PI(4)K to eliminate malaria per Case W. McNamara, Lee M, Chek Shik Lim, Siau Hoi Lim, Jason Roland, A. S. Nagle, Oliver Simon, Bryan K. S. Yeung, Arnab K. Chatterjee, Susan McCormack, Micah J. Manary, Anne‐Marie Zeeman, Koen J. Dechering, T. R. Santha Kumar, Philipp P. Henrich, Kerstin Gagaring, Maureen Ibanez, Nobutaka Kato, Kelli Kuhen, Christoph Fischli, Matthias Rottmann, David Plouffe, Badry Bursulaya, Stephan Meister, Lucia E. Rameh, Joerg Trappe, Dorothea Haasen, Martijn Timmerman, Robert W. Sauerwein, Rossarin Suwanarusk, Bruce Russell, Laurent Rénia, François Nosten, David C. Tully, Clemens H. M. Kocken, Richard Glynne, Christophe Bodenreider, David A. Fidock, Thierry T. Diagana, Elizabeth A. Winzeler
Publicat 2013Artigo
Eines de cerca:
Matèries relacionades
Biochemistry
Biology
Chemistry
Pharmacology
Gene
Medicine
Agonist
Internal medicine
Receptor
Biotechnology
Farnesoid X receptor
Immunology
In vivo
Malaria
Nuclear receptor
Plasmodium falciparum
Transcription factor
Bile acid
Disease
Drug
Endocrinology
Enzyme
Fatty liver
G protein-coupled bile acid receptor
In vitro
Nonalcoholic fatty liver disease
Obeticholic acid
Pharmacokinetics
Plasmodium berghei
Potency