检索结果 - David C. Myles
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Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity 由 Sean W. Fanning, Leslie Hodges-Gallagher, David C. Myles, Richard Sun, Colin Fowler, Isaac N. Plant, B. D. Green, Cyrus L. Harmon, Geoffrey L. Greene, Peter J. Kushner
出版 2018Artigo -
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Palazestrant (OP-1250), A Complete Estrogen Receptor Antagonist, Inhibits Wild-type and Mutant ER-positive Breast Cancer Models as Monotherapy and in Combination 由 Alison D. Parisian, Susanna A. Barratt, Leslie Hodges-Gallagher, Fabian E. Ortega, Guadalupe Peña, Judevin Sapugay, Brandon Robello, Richard Sun, David Kulp, Gopinath S. Palanisamy, David C. Myles, Peter J. Kushner, Cyrus L. Harmon
出版 2023Artigo
相关主题
Biology
Gene
Biochemistry
Breast cancer
Cancer
Cancer research
Chemistry
Estrogen receptor
Internal medicine
Medicine
Methylation
Methyltransferase
Mutant
Pharmacology
Yeast
Antagonist
Antiestrogen
Biosynthesis
Complementation
Ecology
Enzyme
Escherichia coli
Estrogen
Estrogen receptor alpha
Fulvestrant
Genetics
Helix (gastropod)
O-methyltransferase
Receptor
Saccharomyces cerevisiae