Risultati della ricerca - David C. Lowe

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  1. 1
    Current approaches to fine mapping of antigen–antibody interactions

    Current approaches to fine mapping of antigen–antibody interactions di W. Mark Abbott, Melissa Damschroder, David C. Lowe

    Pubblicazione 2014
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  2. 2
    Apoptosis of human intestinal epithelial cells after bacterial invasion.

    Apoptosis of human intestinal epithelial cells after bacterial invasion. di Jung Mogg Kim, Lars Eckmann, Tor Savidge, David C. Lowe, T Witthöft, Martin F. Kagnoff

    Pubblicazione 1998
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  3. 3
    Challenges and opportunities for non-antibody scaffold drugs

    Challenges and opportunities for non-antibody scaffold drugs di Rodrigo Vazquez-Lombardi, Tri Giang Phan, Carsten Zimmermann, David C. Lowe, Lutz Jermutus, Daniel Christ

    Pubblicazione 2015
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  4. 4
    Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens

    Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens di Christopher Lloyd, David C. Lowe, Bryan Edwards, Fraser Welsh, Tess Dilks, Colin Hardman, Tristan J. Vaughan

    Pubblicazione 2008
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  5. 5
    Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production.

    Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and p... di Lars Eckmann, William F. Stenson, Tor Savidge, David C. Lowe, Kim E. Barrett, Joshua Fierer, Jeffrey R. Smith, Martin F. Kagnoff

    Pubblicazione 1997
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  6. 6
    Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell–mediated antibody-dependent cellular cytotoxicity

    Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell–mediated antibody-dependent cellular cytotoxicity di Dominika Rudnicka, Anna Oszmiana, Donna K. Finch, Ian Strickland, Darren J. Schofield, David C. Lowe, Matthew A. Sleeman, Daniel M. Davis

    Pubblicazione 2013
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  7. 7
    Inducing protein aggregation by extensional flow

    Inducing protein aggregation by extensional flow di John Dobson, Amit Kumar, Leon F. Willis, Roman Tůma, Daniel R. Higazi, Richard E. Turner, David C. Lowe, Alison E. Ashcroft, Sheena E. Radford, Nikil Kapur, David J. Brockwell

    Pubblicazione 2017
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  8. 8
    Program Death-1 Engagement Upon TCR Activation Has Distinct Effects on Costimulation and Cytokine-Driven Proliferation: Attenuation of ICOS, IL-4, and IL-21, But Not CD28, IL-7, and IL-15 Responses

    Program Death-1 Engagement Upon TCR Activation Has Distinct Effects on Costimulation and Cytokine-Driven Proliferation: Attenuation of ICOS, IL-4, and IL-21, But Not CD28, IL-7, an... di Frann Bennett, Deborah Luxenberg, Vincent Ling, I‐Ming Wang, Kim Marquette, David C. Lowe, Nighat P. Khan, Geertruida M. Veldman, Kenneth Jacobs, Viia Valge-Archer, Mary Collins, Beatriz M. Carreno

    Pubblicazione 2003
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  9. 9
    Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase

    Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase di Tobias Klein, Navratna Vajpai, Jonathan J. Phillips, Gareth M. Davies, Geoffrey A. Holdgate, Chris Phillips, Julie A. Tucker, Richard A. Norman, Andrew D. Scott, Daniel R. Higazi, David C. Lowe, Gary S. Thompson, Alexander L. Breeze

    Pubblicazione 2015
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  10. 10
    An in vivo platform to select and evolve aggregation-resistant proteins

    An in vivo platform to select and evolve aggregation-resistant proteins di Jessica S. Ebo, Janet C. Saunders, Paul W. A. Devine, Alice M. Gordon, Amy S. Warwick, Bob Schiffrin, Stacey E. Chin, Elizabeth England, James D. Button, Christopher Lloyd, Nicholas J. Bond, Alison E. Ashcroft, Sheena E. Radford, David C. Lowe, David J. Brockwell

    Pubblicazione 2020
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  11. 11
    Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction

    Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction di Elizabeth England, D. Gareth Rees, Ian C. Scott, Sara Carmen, Denice T. Y. Chan, Catherine E. Chaillan Huntington, Kirsty F. Houslay, Teodor Erngren, Mark Penney, Jayesh B. Majithiya, Laura Rapley, Dorothy A. Sims, Claire Hollins, Elizabeth C. Hinchy, Martin Strain, Benjamin Kemp, Dominic J. Corkill, Richard May, Katherine A. Vousden, Robin Butler, Tomas Mustelin, Tristan J. Vaughan, David C. Lowe, Caroline Colley, E. Suzanne Cohen

    Pubblicazione 2023
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  12. 12
    Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo

    Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo di Claire Dobson, Paul W. A. Devine, Jonathan J. Phillips, Daniel R. Higazi, Christopher Lloyd, Bojana Popovic, Joanne Arnold, Andrew Buchanan, Arthur Lewis, Joanne Goodman, Christopher F. van der Walle, Peter Thornton, Lisa Vinall, David Lowne, Anna Aagaard, Lise‐Lotte Olsson, Anna Ridderstad Wollberg, Fraser Welsh, Theodoros K. Karamanos, Clare L. Pashley, M.G. Iadanza, Neil A. Ranson, Alison E. Ashcroft, Alistair D. Kippen, Tristan J. Vaughan, Sheena E. Radford, David C. Lowe

    Pubblicazione 2016
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  13. 13
    Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

    Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation di E. Suzanne Cohen, Ian C. Scott, Jayesh B. Majithiya, Laura Rapley, Benjamin Kemp, Elizabeth England, D. Gareth Rees, Catherine L. Overed‐Sayer, Joanne Woods, Nicholas J. Bond, Christel Séguy Veyssier, Kevin J. Embrey, Dorothy A. Sims, Michael Snaith, Katherine A. Vousden, Martin Strain, Denice T. Y. Chan, Sara Carmen, Catherine E. Chaillan Huntington, Liz Flavell, Jianqing Xu, Bojana Popovic, Christopher E. Brightling, Tristan J. Vaughan, Robin Butler, David C. Lowe, Daniel R. Higazi, Dominic J. Corkill, Richard May, Matthew A. Sleeman, Tomas Mustelin

    Pubblicazione 2015
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  14. 14
    A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

    A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope di Michael D. Miller, Romas Geleziunas, Elisabetta Bianchi, Simon Lennard, Renee Hrin, Hangchun Zhang, Meiqing Lu, Zhiqiang An, Paolo Ingallinella, Marco Finotto, Marco Mattu, Adam C. Finnefrock, David Bramhill, James C. Cook, Debra M. Eckert, Richard Hampton, Mayuri Patel, Stephen Jarantow, Joseph G. Joyce, Gennaro Ciliberto, Riccardo Cortese, Ping Lu, William R. Strohl, William A. Schleif, Michael McElhaugh, Steven Lane, Christopher Lloyd, David C. Lowe, Jane Osbourn, Tristan J. Vaughan, Emilio A. Emini, Gaetano Barbato, Peter S. Kim, Daria J. Hazuda, John W. Shiver, Antonello Pessi

    Pubblicazione 2005
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  15. 15
    The INNs and outs of antibody nonproprietary names

    The INNs and outs of antibody nonproprietary names di Tim D. Jones, Paul J. Carter, Andreas Plückthun, Max Vásquez, Robert Holgate, Isidro Hötzel, Andrew G. Popplewell, Paul W.H.I. Parren, Markus Enzelberger, Hendrik J. Rademaker, Mike Clark, David C. Lowe, Bassil I. Dahiyat, Victoria Smith, John M. Lambert, Herren Wu, Mary M. Reilly, John S. Haurum, Stefan Dübel, James S. Huston, Thomas Schirrmann, Richard A. J. Janssen, Martin Steegmaier, Jane A. Gross, Andrew Bradbury, Dennis R. Burton, Dimiter S. Dimitrov, Kerry Chester, Martin J. Glennie, Julian Davies, A. P. WALKER, Steve L. Martin, John McCafferty, Matthew Baker

    Pubblicazione 2015
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  16. 16
    De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

    De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8 di Anindya Roy, Lei Shi, Ashley Chang, Xianchi Dong, Andres Fernandez, John C. Kraft, Jing Li, Viet Q. Le, Rebecca Viazzo Winegar, Gerald Maxwell Cherf, Dean Slocum, P. Daniel Poulson, Garrett E. Casper, Mary L. Vallecillo-Zúniga, Jonard Corpuz Valdoz, Marcos C. Miranda, Hua Bai, Yakov Kipnis, Audrey Olshefsky, Tanu Priya, Lauren Carter, Rashmi Ravichandran, Cameron M. Chow, Max Johnson, Suna Cheng, McKaela Smith, Catherine Overed-Sayer, Donna K. Finch, David C. Lowe, Asim K. Bera, Gustavo Matute‐Bello, Timothy P. Birkland, Frank DiMaio, Ganesh Raghu, Jennifer R. Cochran, Lance Stewart, Melody G. Campbell, Pam M. Van Ry, Timothy A. Springer, David Baker

    Pubblicazione 2023
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