Resultats de la cerca - David Brough

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  1. 1
    Interleukin‐1α and brain inflammation

    Interleukin‐1α and brain inflammation per David Brough, Ádám Dénes

    Publicat 2015
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  2. 2
    The role of inflammation and interleukin-1 in acute cerebrovascular disease

    The role of inflammation and interleukin-1 in acute cerebrovascular disease per David Brough, James Galea

    Publicat 2013
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  3. 3
    Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways

    Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways per Jack Rivers‐Auty, David Brough

    Publicat 2015
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  4. 4
    Understanding the mechanism of IL-1β secretion

    Understanding the mechanism of IL-1β secretion per Gloria López‐Castejón, David Brough

    Publicat 2011
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  5. 5
    Unconventional Pathways of Secretion Contribute to Inflammation

    Unconventional Pathways of Secretion Contribute to Inflammation per Michael J. Daniels, David Brough

    Publicat 2017
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  6. 6
    Dual functionality of interleukin‐1 family cytokines: implications for anti‐interleukin‐1 therapy

    Dual functionality of interleukin‐1 family cytokines: implications for anti‐interleukin‐1 therapy per NM Luheshi, NJ Rothwell, David Brough

    Publicat 2009
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  7. 7
    Inflammasomes link vascular disease with neuroinflammation and brain disorders

    Inflammasomes link vascular disease with neuroinflammation and brain disorders per Nikolett Lénárt, David Brough, Ádám Dénes

    Publicat 2016
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  8. 8
    An emerging case for membrane pore formation as a common mechanism for the unconventional secretion of FGF2 and IL-1β

    An emerging case for membrane pore formation as a common mechanism for the unconventional secretion of FGF2 and IL-1β per David Brough, Pablo Pelegrı́n, Walter Nickel

    Publicat 2017
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  9. 9
    Pannexin‐1‐dependent caspase‐1 activation and secretion of IL‐1β is regulated by zinc

    Pannexin‐1‐dependent caspase‐1 activation and secretion of IL‐1β is regulated by zinc per David Brough, Pablo Pelegrı́n, Nancy J. Rothwell

    Publicat 2009
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  10. 10
    Caspase-1: is IL-1 just the tip of the ICEberg?

    Caspase-1: is IL-1 just the tip of the ICEberg? per Ádám Dénes, Gloria López‐Castejón, David Brough

    Publicat 2012
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  11. 11
    Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility

    Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility per David Brough, Michael J. Schell, Robin F. Irvine

    Publicat 2005
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  12. 12
    Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide

    Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide per Catherine B. Lawrence, David Brough, Elysse M. Knight

    Publicat 2012
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  13. 13
    Inhibiting the NLRP3 Inflammasome

    Inhibiting the NLRP3 Inflammasome per Lina Y. El‐Sharkawy, David Brough, Sally Freeman

    Publicat 2020
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  14. 14
    Sphingosine regulates the NLRP3‐inflammasome and IL‐1<b>β</b> release from macrophages

    Sphingosine regulates the NLRP3‐inflammasome and IL‐1<b>β</b> release from macrophages per Nadia Luheshi, James Giles, Gloria López‐Castejón, David Brough

    Publicat 2011
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  15. 15
    Microglial Priming as Trained Immunity in the Brain

    Microglial Priming as Trained Immunity in the Brain per Michael Haley, David Brough, Jessica Quintin, Stuart M. Allan

    Publicat 2017
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  16. 16
    Mechanisms of NLRP3 priming in inflammaging and age related diseases

    Mechanisms of NLRP3 priming in inflammaging and age related diseases per Anna Gritsenko, Jack Green, David Brough, Gloria López‐Castejón

    Publicat 2020
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  17. 17
    Novel perspectives on non-canonical inflammasome activation

    Novel perspectives on non-canonical inflammasome activation per Catherine Emma Diamond, Hanif Javanmard Khameneh, David Brough, Alessandra Mortellaro

    Publicat 2015
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  18. 18
    NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

    NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury per Catherine Diane Savage, Gloria López‐Castejón, Ádám Dénes, David Brough

    Publicat 2012
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  19. 19
    Inflammasomes as therapeutic targets for <scp>A</scp>lzheimer's disease

    Inflammasomes as therapeutic targets for <scp>A</scp>lzheimer's disease per Claire White, Catherine B. Lawrence, David Brough, Jack Rivers‐Auty

    Publicat 2016
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  20. 20
    Role of P2X<sub>7</sub>Receptors in Ischemic and Excitotoxic Brain Injury<i>In Vivo</i>

    Role of P2X<sub>7</sub>Receptors in Ischemic and Excitotoxic Brain Injury<i>In Vivo</i> per Rosalind A. Le Feuvre, David Brough, Omar Touzani, Nancy J. Rothwell

    Publicat 2003
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