檢索結果 - David B. Darr

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  1. 1
    Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model

    Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model 由 Christin E. Burd, Jessica A. Sorrentino, Kelly S. Clark, David B. Darr, Janakiraman Krishnamurthy, Allison M. Deal, Nabeel Bardeesy, Diego H. Castrillón, David Beach, Norman E. Sharpless

    出版 2013
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  2. 2
    The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus

    The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus 由 Sharareh Siamakpour‐Reihani, Joseph M. Caster, Desh Bandhu Nepal, Andrew Courtwright, Eleanor Hilliard, Jerry Usary, David Ketelsen, David B. Darr, Xiang Shen, Cam Patterson, Nancy Klauber‐DeMore

    出版 2011
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  3. 3
    Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: Preparation, in vitro and in vivo evaluation

    Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: Preparation, in vitro and in vivo evaluation 由 Zhijian He, Anita Schulz, Xiaomeng Wan, Joshua D. Seitz, Herdis Bludau, Daria Y. Alakhova, David B. Darr, Charles M. Perou, Rainer Jordan, Iwao Ojima, Alexander V. Kabanov, Robert Luxenhofer

    出版 2015
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  4. 4
    Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy

    Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy 由 Patrick J. Roberts, John E. Bisi, Jay C. Strum, Austin J. Combest, David B. Darr, Jerry Usary, William C. Zamboni, Kwok‐Kin Wong, Charles M. Perou, Norman E. Sharpless

    出版 2012
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  5. 5
    New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging

    New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging 由 Hailey E. Brighton, Steven P. Angus, Tao Bo, Jose Roques, Alicia C. Tagliatela, David B. Darr, Kübra Karagoz, Noah Sciaky, Michael L. Gatza, Norman E. Sharpless, Gary L. Johnson, James E. Bear

    出版 2017
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  6. 6
    Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells

    Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells 由 Jason I. Herschkowitz, Wei Zhao, Mei Zhang, Jerry Usary, George Murrow, David G. Edwards, Jana Knezevic, Stephanie Greene, David B. Darr, Melissa A. Troester, Susan G. Hilsenbeck, Daniel Medina, Charles M. Perou, Jeffrey M. Rosen

    出版 2011
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  7. 7
    Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2 + Breast Cancer

    Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2 + Breast Cancer 由 Yazan Alwarawrah, Philip F. Hughes, David R. Loiselle, David A. Carlson, David B. Darr, Jamie L. Jordan, Jessie Xiong, Lucas Hunter, Laura G. Dubois, J. Will Thompson, Manjusha Kulkarni, Annette N. Ratcliff, Jesse J. Kwiek, Timothy Haystead

    出版 2016
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  8. 8
    Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling

    Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling 由 Ronald L. Chandler, Jeffrey S. Damrauer, Jesse R. Raab, Jonathan C. Schisler, Matthew D. Wilkerson, John P. Didion, Joshua Starmer, Daniel Serber, Della Yee, Jessie Xiong, David B. Darr, Fernando Pardo‐Manuel de Villena, William Y. Kim, Terry Magnuson

    出版 2015
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  9. 9
    Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer

    Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer 由 Carey K. Anders, Bárbara Adamo, Olga Karginova, Allison M. Deal, Sumit Rawal, David B. Darr, Allison N. Schorzman, Charlene Santos, Ryan Bash, Tal Kafri, Lisa A. Carey, C. Ryan Miller, Charles M. Perou, Norman E. Sharpless, William C. Zamboni

    出版 2013
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  10. 10
    Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models

    Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models 由 Patrick J. Roberts, Jerry Usary, David B. Darr, Patrick M. Dillon, Adam D. Pfefferle, Martin C. Whittle, James S. Duncan, Søren M. Johnson, Austin J. Combest, Jian Jin, William C. Zamboni, Gary L. Johnson, Charles M. Perou, Norman E. Sharpless

    出版 2012
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  11. 11
    Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal

    Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal 由 Bing Zhou, Jeffrey S. Damrauer, Sean T. Bailey, Tanja Hadzic, Youngtae Jeong, Kelly S. Clark, Huihui Fan, Laura Murphy, Cleo Y. Lee, Melissa A. Troester, C. Ryan Miller, Jian Jin, David B. Darr, Charles M. Perou, Ross L. Levine, Maximilian Diehn, William Y. Kim

    出版 2014
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  12. 12
    Identification of an Allosteric Small-Molecule Inhibitor Selective for the Inducible Form of Heat Shock Protein 70

    Identification of an Allosteric Small-Molecule Inhibitor Selective for the Inducible Form of Heat Shock Protein 70 由 Matthew K. Howe, Khaldon Bodoor, David A. Carlson, Philip F. Hughes, Yazan Alwarawrah, David R. Loiselle, Alex M. Jaeger, David B. Darr, Jamie L. Jordan, Lucas Hunter, Eileen T. Molzberger, Theodore A. Gobillot, Dennis J. Thiele, Jeffrey L. Brodsky, Neil L. Spector, Timothy Haystead

    出版 2014
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  13. 13
    Mutation-Specific RAS Oncogenicity Explains NRAS Codon 61 Selection in Melanoma

    Mutation-Specific RAS Oncogenicity Explains NRAS Codon 61 Selection in Melanoma 由 Christin E. Burd, Wenjin Liu, Minh V. Huynh, Meriam A. Waqas, James E. Gillahan, Kelly S. Clark, Kailing Fu, Brit L. Martin, William R. Jeck, George P. Souroullas, David B. Darr, Daniel C. Zedek, Michael J. Miley, Bruce C. Baguley, Sharon L. Campbell, Norman E. Sharpless

    出版 2014
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  14. 14
    Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice

    Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice 由 Jerry Usary, Wei Zhao, David B. Darr, Patrick J. Roberts, Mei Liu, Lorraine Balletta, Olga Karginova, Jamie Jordan, Austin J. Combest, Arlene S. Bridges, Aleix Prat, Maggie C.U. Cheang, Jason I. Herschkowitz, Jeffrey M. Rosen, William C. Zamboni, Norman E. Sharpless, Charles M. Perou

    出版 2013
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  15. 15
    A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer

    A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer 由 Ning Cheng, Rebekah Watkins-Schulz, Robert D. Junkins, Clément N. David, Brandon M. Johnson, Stephanie A. Montgomery, Kevin J. Peine, David B. Darr, Hong Yuan, Karen P. McKinnon, Qi Liu, Lei Miao, Leaf Huang, Eric M. Bachelder, Kristy M. Ainslie, Jenny P.‐Y. Ting

    出版 2018
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  16. 16
    Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of <i>BRCA</i>-Mutated and <i>BRCA</i>–Wild-Type Triple-Negative Breast Cancer

    Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of <i>BRCA</i>-Mutated and <i>BRCA</i>–Wild-Type Triple-Negative Breast Cancer 由 Olga Karginova, Marni B. Siegel, Amanda E.D. Van Swearingen, Allison M. Deal, Bárbara Adamo, Maria J. Sambade, Soha Bazyar, Nana Nikolaishvili‐Feinberg, Ryan Bash, Sara O’Neal, Katie Sandison, Joel S. Parker, Charlene Santos, David B. Darr, William C. Zamboni, Yueh Z. Lee, C. Ryan Miller, Carey K. Anders

    出版 2015
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  17. 17
    Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy

    Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy 由 Aadra P. Bhatt, Samuel J. Pellock, Kristen A. Biernat, William G. Walton, Bret D. Wallace, Benjamin C. Creekmore, Marine P. M. Letertre, Jonathan R. Swann, Ian D. Wilson, Jose Roques, David B. Darr, Sean T. Bailey, Stephanie A. Montgomery, Jeffrey Roach, M. Andrea Azcárate-Peril, R. Balfour Sartor, Raad Z. Gharaibeh, Scott J. Bultman, Matthew R. Redinbo

    出版 2020
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  18. 18
    Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex

    Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex 由 Jon S. Zawistowski, Samantha M. Bevill, Daniel R. Goulet, Timothy J. Stuhlmiller, Adriana S. Beltrán, José F. Olivares-Quintero, Darshan Singh, Noah Sciaky, Joel S. Parker, Naim U. Rashid, Xin Chen, James S. Duncan, Martin C. Whittle, Steven P. Angus, Sara H. Velarde, Brian T. Golitz, Xiaping He, Charlene Santos, David B. Darr, Kristalyn Gallagher, Lee M. Graves, Charles M. Perou, Lisa A. Carey, H. Shelton Earp, Gary L. Johnson

    出版 2017
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  19. 19
    Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

    Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer 由 John S. Duncan, Martin C. Whittle, Kazuhiro Nakamura, Amy N. Abell, Alicia A. Midland, Jon S. Zawistowski, Nancy L. Johnson, Deborah A. Granger, Nicole Vincent Jordan, David B. Darr, Jerry Usary, Pei Fen Kuan, David M. Smalley, Michael B. Major, Xiaping He, Katherine A. Hoadley, Bing Zhou, Norman E. Sharpless, Charles M. Perou, William Y. Kim, Shawn M. Gomez, Xin Chen, Jian Jin, Stephen V. Frye, H. Shelton Earp, Lee M. Graves, Gary L. Johnson

    出版 2012
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  20. 20
    A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

    A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma 由 Clemens Krepler, Katrin Sproesser, Patricia Brafford, Marilda Beqiri, Bradley Garman, Min Xiao, Batool Shannan, Andrea Watters, Michela Perego, Gao Zhang, Adina Vultur, Xiangfan Yin, Qin Liu, Ioannis N. Anastopoulos, Bradley Wubbenhorst, Melissa Wilson, Wei Xu, Giorgos C. Karakousis, Michael D. Feldman, Xiaowei Xu, Ravi K. Amaravadi, Tara C. Gangadhar, David E. Elder, Lauren E. Haydu, Jennifer A. Wargo, Michael A. Davies, Yiling Lu, Gordon B. Mills, Dennie T. Frederick, Michal Barzily-Rokni, Keith T. Flaherty, Dave S.�B. Hoon, Michael J. Guarino, Joseph Bennett, R Ryan, Nicholas J. Petrelli, Carol L. Shields, Mizue Terai, Takami Sato, Andrew E. Aplin, Alexander Roesch, David B. Darr, Steven P. Angus, Rakesh Kumar, Ensar Halilovic, Giordano Caponigro, Sébastien Jeay, Jens Wuerthner, Annette O. Walter, Matthias Ocker, Matthew B. Boxer, Lynn M. Schuchter, Katherine L. Nathanson, Meenhard Herlyn

    出版 2017
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