Canlyniadau Chwilio - David Alvarez-Carbonell
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HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency gan George N. Llewellyn, David Alvarez-Carbonell, Morgan Chateau, Jonathan Karn, Paula M. Cannon
Cyhoeddwyd 2017Artigo -
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Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells gan Fengchun Ye, David Alvarez-Carbonell, Kien Nguyen, Konstantin Leskov, Yoelvis García‐Mesa, Sheetal Sreeram, Saba Valadkhan, Jonathan Karn
Cyhoeddwyd 2022Artigo -
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Magnetically guided non-invasive CRISPR-Cas9/gRNA delivery across blood-brain barrier to eradicate latent HIV-1 infection gan Ajeet Kaushik, Adriana Yndart, Venkata Atluri, Sneham Tiwari, Asahi Tomitaka, Purnima Gupta, Rahul Dev Jayant, David Alvarez-Carbonell, Kamel Khalili, Madhavan Nair
Cyhoeddwyd 2019Artigo -
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CRISPR-Cas9 Mediated TSPO Gene Knockout alters Respiration and Cellular Metabolism in Human Primary Microglia Cells gan Vladimir M. Milenkovic, Dounia Slim, Stefanie M. Bader, Victoria Koch, Elena-Sofia Heinl, David Alvarez-Carbonell, Caroline Nothdurfter, Rainer Rupprecht, Christian H. Wetzel
Cyhoeddwyd 2019Artigo -
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Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system gan Yoelvis García‐Mesa, Taylor R. Jay, Mary Ann Checkley, Benjamin G. Luttge, Curtis Dobrowolski, Saba Valadkhan, Gary E. Landreth, Jonathan Karn, David Alvarez-Carbonell
Cyhoeddwyd 2016Artigo -
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RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection gan Wenhui Hu, Rafal Kaminski, Fan Yang, Yonggang Zhang, L.Mark Cosentino, Fang Li, Biao Luo, David Alvarez-Carbonell, Yoelvis García‐Mesa, Jonathan Karn, Xianming Mo, Kamel Khalili
Cyhoeddwyd 2014Artigo -
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Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress gan Iart Luca Shytaj, Francesco A. Procopio, Mohammad Tarek, Irene Carlón-Andrés, Hsin‐Yao Tang, Aaron R. Goldman, MohamedHusen Munshi, Mattia Forcato, Konstantin Leskov, Fengchun Ye, Bojana Lucic, Nicolly Cruz, Amit Singh, Silvio Bicciato, Sergi Padilla‐Parra, Marina Lušić, Ricardo Sobhie Diaz, David Alvarez-Carbonell, Andrea Savarino
Cyhoeddwyd 2020Pré-impressão -
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Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress gan Iart Luca Shytaj, Francesco A. Procopio, Mohammad Tarek, Irene Carlón-Andrés, Hsin‐Yao Tang, Aaron R. Goldman, MohamedHusen Munshi, Virender Kumar Pal, Mattia Forcato, Sheetal Sreeram, Konstantin Leskov, Fengchun Ye, Bojana Lucic, Nicolly Cruz, Lishomwa C. Ndhlovu, Silvio Bicciato, Sergi Padilla‐Parra, Ricardo Sobhie Diaz, Amit Singh, Marina Lušić, Jonathan Karn, David Alvarez-Carbonell, Andrea Savarino
Cyhoeddwyd 2021Artigo
Offerynnau Chwilio:
Pynciau Perthynol
Biology
Immunology
Cell biology
Inflammation
Microglia
Virology
Gene
Biochemistry
Neuroscience
Gene expression
Genetics
Viral replication
Virus
Virus latency
CRISPR
Cas9
Central nervous system
Computational biology
Downregulation and upregulation
Enzyme
Gene silencing
Glycolysis
Immune system
Medicine
Metabolism
Myeloid
NAD+ kinase
Oxidative stress
Pentose phosphate pathway
Receptor