Výsledky vyhledávání - Dar, Arvin

Small Molecule Recognition of c-Src via the Imatinib-Binding Conformation Autor Dar, Arvin C., Lopez, Michael S., Shokat, Kevan M.

Získat plný text Získat plný text Získat plný text

Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling Autor Dhawan, Neil S., scopton, Alex P., Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

Understanding and drugging RAS: 40 years to break the tip of the iceberg Autor Brady, Donita C., Hmeljak, Julija, Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

Ploidy Leads a Molecular Motor to Walk Different Paths to Drug Resistance Autor Real, Alexander M., Marsiglia, William M., Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

Conformational control and regulation of the pseudokinase KSR via small molecule binding interactions Autor Chow, Arthur, Khan, Zaigham M., Marsiglia, William M., Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology Autor Dar, Arvin C., Das, Tirtha K., Shokat, Kevan M., Cagan, Ross L.

Získat plný text Získat plný text Získat plný text

Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network Autor Ung, Peter M. U., Sonoshita, Masahiro, Scopton, Alex P., Dar, Arvin C., Cagan, Ross L., Schlessinger, Avner

Získat plný text Získat plný text Získat plný text

Slipped-strand DNAs formed by long (CAG)·(CTG) repeats: slipped-out repeats and slip-out junctions Autor Pearson, Christopher E., Tam, Mandy, Wang, Yuh-Hwa, Montgomery, S. Erin, Dar, Arvin C., Cleary, John D., Nichol, Kerrie

Získat plný text Získat plný text

Chemical Genetic Approach for Kinase-Substrate Mapping by Covalent Capture of Thiophosphopeptides and Analysis by Mass Spectrometry Autor Hertz, Nicholas T., Wang, Beatrice T., Allen, Jasmina J., Zhang, Chao, Dar, Arvin C., Burlingame, Alma L., Shokat, Kevan M.

Získat plný text Získat plný text Získat plný text

Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein Autor Seo, Eun Joo, Liu, Furong, Kawagishi-Kobayashi, Makiko, Ung, Tekly L., Cao, Chune, Dar, Arvin C., Sicheri, Frank, Dever, Thomas E.

Získat plný text Získat plný text Získat plný text

Structure-guided Inhibitor Design Expands the Scope of Analog-Sensitive Kinase Technology Autor Zhang, Chao, Lopez, Michael S., Dar, Arvin C., LaDow, Eva, Finkbeiner, Steven, Yun, Cai-Hong, Eck, Michael J., Shokat, Kevan M.

Získat plný text Získat plný text Získat plný text

CNS Anticancer Drug Discovery and Development: 2016 conference insights Autor Levin, Victor A, Abrey, Lauren E, Heffron, Timothy P, Tonge, Peter J, Dar, Arvin C, Weiss, William A, Gallo, James M

Získat plný text Získat plný text Získat plný text

Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors Autor Israelow, Benjamin, Mullokandov, Gavriel, Agudo, Judith, Sourisseau, Marion, Bashir, Ali, Maldonado, Andres Y., Dar, Arvin C., Brown, Brian D., Evans, Matthew J.

Získat plný text Získat plný text Získat plný text

PKR and GCN2 Kinases and Guanine Nucleotide Exchange Factor Eukaryotic Translation Initiation Factor 2B (eIF2B) Recognize Overlapping Surfaces on eIF2α Autor Dey, Madhusudan, Trieselmann, Bruce, Locke, Emily G., Lu, Jingfang, Cao, Chune, Dar, Arvin C., Krishnamoorthy, Thanuja, Dong, Jinsheng, Sicheri, Frank, Dever, Thomas E.

Získat plný text Získat plný text Získat plný text

Structural basis for the action of the drug trametinib at KSR-bound MEK Autor Khan, Zaigham M., Real, Alexander M., Marsiglia, William M., Chow, Arthur, Duffy, Mary E., Yerabolu, Jayasudhan R., Scopton, Alex P., Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

Type II Binders Targeting the “GLR-out” Conformation of the Pseudokinase STRADα Autor Smith, Ryan H.B., Khan, Zaigham M., Ung, Peter Man-Un, Scopton, Alex, Silber, Lisa, Mack, Seshat M., Real, Alexander, Schlessinger, Avner, Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space Autor Sonoshita, Masahiro, Scopton, Alex P., Ung, Peter M-U., Murray, Matthew A., Silber, Lisa, Maldonado, Andres Y., Real, Alexander, Schlessinger, Avner, Cagan, Ross L., Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic Autor Mendez, Aaron S, Alfaro, Jennifer, Morales-Soto, Marisol A, Dar, Arvin C, McCullagh, Emma, Gotthardt, Katja, Li, Han, Acosta-Alvear, Diego, Sidrauski, Carmela, Korennykh, Alexei V, Bernales, Sebastian, Shokat, Kevan M, Walter, Peter

Získat plný text Získat plný text Získat plný text

Phenotype-based screens with conformation-specific inhibitors reveal p38 gamma and delta as targets for HCC polypharmacology Autor Yu, Jia Xin, Craig, Amanda J., Duffy, Mary E., Villacorta-Martin, Carlos, Miguela, Verónica, de Galarreta, Marina Ruiz, Scopton, Alexander P., Silber, Lisa, Maldonado, Andres Y., Rialdi, Alexander, Guccione, Ernesto, Lujambio, Amaia, Villanueva, Augusto, Dar, Arvin C.

Získat plný text Získat plný text Získat plný text

CNS Anticancer Drug Discovery and Development Conference White Paper Autor Levin, Victor A., Tonge, Peter J., Gallo, James M., Birtwistle, Marc R., Dar, Arvin C., Iavarone, Antonio, Paddison, Patrick J., Heffron, Timothy P., Elmquist, William F., Lachowicz, Jean E., Johnson, Ted W., White, Forest M., Sul, Joohee, Smith, Quentin R., Shen, Wang, Sarkaria, Jann N., Samala, Ramakrishna, Wen, Patrick Y., Berry, Donald A., Petter, Russell C.

Získat plný text Získat plný text Získat plný text