检索结果 - Dankort, David

Ras Effector Mutant Expression Suggest a Negative Regulator Inhibits Lung Tumor Formation 由 Vandal, Guillaume, Geiling, Benjamin, Dankort, David

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TP53 Silencing Bypasses Growth Arrest of BRAF(V600E)-Induced Lung Tumor Cells In a Two-Switch Model of Lung Tumorigenesis 由 Shai, Anny, Dankort, David, Juan, Joseph, Green, Shon, McMahon, Martin

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Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse 由 Charles, Roch-Philippe, Iezza, Gioia, Amendola, Elena, Dankort, David, McMahon, Martin

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A new mouse model to explore the initiation, progression, and therapy of BRAF(V600E)-induced lung tumors 由 Dankort, David, Filenova, Elena, Collado, Manuel, Serrano, Manuel, Jones, Kirk, McMahon, Martin

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Characterization of Melanoma Cells Capable of Propagating Tumors from a Single Cell 由 Held, Matthew A., Curley, David P., Dankort, David, McMahon, Martin, Muthusamy, Viswanathan, Bosenberg, Marcus W.

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A Modular Lentiviral and Retroviral Construction System to Rapidly Generate Vectors for Gene Expression and Gene Knockdown In Vitro and In Vivo 由 Geiling, Benjamin, Vandal, Guillaume, Posner, Ada R., de Bruyns, Angeline, Dutchak, Kendall L., Garnett, Samantha, Dankort, David

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Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720 由 Kamata, Tamihiro, Dankort, David, Kang, Jing, Giblett, Susan, Pritchard, Catrin A., McMahon, Martin, Leavitt, Andrew D.

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Functional relevance of the histone γH2Ax in the response to DNA damaging agents 由 Revet, Ingrid, Feeney, Luzviminda, Bruguera, Stephanie, Wilson, Wade, Dong, Tiffany K., Oh, Dennis H., Dankort, David, Cleaver, James E.

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HGF Converts ErbB2/Neu Epithelial Morphogenesis to Cell Invasion 由 Khoury, Hanane, Naujokas, Monica A., Zuo, Dongmei, Sangwan, Veena, Frigault, Melanie M., Petkiewicz, Stephanie, Dankort, David L., Muller, William J., Park, Morag

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Oncogene dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma 由 Mito, Jeffrey K., Min, Hooney D., Ma, Yan, Carter, Jessica E., Brigman, Brian E., Dodd, Leslie, Dankort, David, McMahon, Martin, Kirsch, David G.

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Grb2 and Shc Adapter Proteins Play Distinct Roles in Neu (ErbB-2)-Induced Mammary Tumorigenesis: Implications for Human Breast Cancer 由 Dankort, David, Maslikowski, Bart, Warner, Neil, Kanno, Nubufumi, Kim, Harold, Wang, Zhixiang, Moran, Michael F., Oshima, Robert G., Cardiff, Robert D., Muller, William J.

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The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis 由 Saucier, Caroline, Khoury, Hanane, Lai, Ka-Man Venus, Peschard, Pascal, Dankort, David, Naujokas, Monica A., Holash, Jocelyn, Yancopoulos, George D., Muller, William J., Pawson, Tony, Park, Morag

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BRaf(V600E) cooperates with Pten silencing to elicit metastatic melanoma 由 Dankort, David, Curley, David P., Cartlidge, Robert A., Nelson, Betsy, Karnezis, Anthony N., Damsky, William E., You, Mingjian J., DePinho, Ronald A., McMahon, Martin, Bosenberg, Marcus

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RAS Transformation Requires CUX1-Dependent Repair of Oxidative DNA Damage 由 Ramdzan, Zubaidah M., Vadnais, Charles, Pal, Ranjana, Vandal, Guillaume, Cadieux, Chantal, Leduy, Lam, Davoudi, Sayeh, Hulea, Laura, Yao, Lu, Karnezis, Anthony N., Paquet, Marilène, Dankort, David, Nepveu, Alain

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β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas 由 Damsky, William E., Curley, David P., Santhanakrishnan, Manjula, Rosenbaum, Lara E., Platt, James T., Gould Rothberg, Bonnie E., Taketo, Makoto M., Dankort, David, Rimm, David L., McMahon, Martin, Bosenberg, Marcus

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Abrogation of BRAF(V600E)-induced senescence by PI3K pathway activation contributes to melanomagenesis 由 Vredeveld, Liesbeth C.W., Possik, Patricia A., Smit, Marjon A., Meissl, Katrin, Michaloglou, Chrysiis, Horlings, Hugo M., Ajouaou, Abderrahim, Kortman, Pim C., Dankort, David, McMahon, Martin, Mooi, Wolter J., Peeper, Daniel S.

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B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer 由 Wang, Jingqiang, Kobayashi, Takashi, Floc'h, Nicolas, Kinkade, Carolyn Waugh, Aytes, Alvaro, Dankort, David, Lefebvre, Celine, Mitrofanova, Antonina, Cardiff, Robert D., McMahon, Martin, Califano, Andrea, Shen, Michael M., Abate-Shen, Cory

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A Central Role for RAF→MEK→ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma. 由 Collisson, Eric A., Trejo, Christy, Silva, Jillian, Gu, Shenda, Korkola, James E., Heiser, Laura, Charles, Roch-Philippe, Rabinovich, Brian A., Hann, Byron, Dankort, David, Spellman, Paul T., Phillips, Wayne, Gray, Joe W., McMahon, Martin

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mTORC1 activation blocks Braf(V600E)-induced growth-arrest, but is insufficient for melanoma formation 由 Damsky, William, Micevic, Goran, Meeth, Katrina, Muthusamy, Viswanathan, Curley, David P., Santhankrishnan, Manjula, Erdelyi, Ildiko, Platt, James T., Huang, Laura, Theodosakis, Nicholas, Zaidi, M. Raza, Tighe, Scott, Davies, Michael A., Dankort, David, McMahon, Martin, Merlino, Glenn, Bardeesy, Nabeel, Bosenberg, Marcus

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Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses 由 Huang, Fan, Gonçalves, Christophe, Bartish, Margarita, Rémy-Sarrazin, Joelle, Issa, Mark E., Cordeiro, Brendan, Guo, Qianyu, Emond, Audrey, Attias, Mikhael, Yang, William, Plourde, Dany, Su, Jie, Gimeno, Marina Godoy, Zhan, Yao, Galán, Alba, Rzymski, Tomasz, Mazan, Milena, Masiejczyk, Magdalena, Faber, Jacek, Khoury, Elie, Benoit, Alexandre, Gagnon, Natascha, Dankort, David, Journe, Fabrice, Ghanem, Ghanem E., Krawczyk, Connie M., Saragovi, H. Uri, Piccirillo, Ciriaco A., Sonenberg, Nahum, Topisirovic, Ivan, Rudd, Christopher E., Miller, Wilson H., del Rincón, Sonia V.

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