Ngā hua rapu - Dankort, David

Ras Effector Mutant Expression Suggest a Negative Regulator Inhibits Lung Tumor Formation mā Vandal, Guillaume, Geiling, Benjamin, Dankort, David

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TP53 Silencing Bypasses Growth Arrest of BRAF(V600E)-Induced Lung Tumor Cells In a Two-Switch Model of Lung Tumorigenesis mā Shai, Anny, Dankort, David, Juan, Joseph, Green, Shon, McMahon, Martin

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Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse mā Charles, Roch-Philippe, Iezza, Gioia, Amendola, Elena, Dankort, David, McMahon, Martin

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A new mouse model to explore the initiation, progression, and therapy of BRAF(V600E)-induced lung tumors mā Dankort, David, Filenova, Elena, Collado, Manuel, Serrano, Manuel, Jones, Kirk, McMahon, Martin

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Characterization of Melanoma Cells Capable of Propagating Tumors from a Single Cell mā Held, Matthew A., Curley, David P., Dankort, David, McMahon, Martin, Muthusamy, Viswanathan, Bosenberg, Marcus W.

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A Modular Lentiviral and Retroviral Construction System to Rapidly Generate Vectors for Gene Expression and Gene Knockdown In Vitro and In Vivo mā Geiling, Benjamin, Vandal, Guillaume, Posner, Ada R., de Bruyns, Angeline, Dutchak, Kendall L., Garnett, Samantha, Dankort, David

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Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720 mā Kamata, Tamihiro, Dankort, David, Kang, Jing, Giblett, Susan, Pritchard, Catrin A., McMahon, Martin, Leavitt, Andrew D.

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Functional relevance of the histone γH2Ax in the response to DNA damaging agents mā Revet, Ingrid, Feeney, Luzviminda, Bruguera, Stephanie, Wilson, Wade, Dong, Tiffany K., Oh, Dennis H., Dankort, David, Cleaver, James E.

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HGF Converts ErbB2/Neu Epithelial Morphogenesis to Cell Invasion mā Khoury, Hanane, Naujokas, Monica A., Zuo, Dongmei, Sangwan, Veena, Frigault, Melanie M., Petkiewicz, Stephanie, Dankort, David L., Muller, William J., Park, Morag

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Oncogene dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma mā Mito, Jeffrey K., Min, Hooney D., Ma, Yan, Carter, Jessica E., Brigman, Brian E., Dodd, Leslie, Dankort, David, McMahon, Martin, Kirsch, David G.

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Grb2 and Shc Adapter Proteins Play Distinct Roles in Neu (ErbB-2)-Induced Mammary Tumorigenesis: Implications for Human Breast Cancer mā Dankort, David, Maslikowski, Bart, Warner, Neil, Kanno, Nubufumi, Kim, Harold, Wang, Zhixiang, Moran, Michael F., Oshima, Robert G., Cardiff, Robert D., Muller, William J.

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The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis mā Saucier, Caroline, Khoury, Hanane, Lai, Ka-Man Venus, Peschard, Pascal, Dankort, David, Naujokas, Monica A., Holash, Jocelyn, Yancopoulos, George D., Muller, William J., Pawson, Tony, Park, Morag

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BRaf(V600E) cooperates with Pten silencing to elicit metastatic melanoma mā Dankort, David, Curley, David P., Cartlidge, Robert A., Nelson, Betsy, Karnezis, Anthony N., Damsky, William E., You, Mingjian J., DePinho, Ronald A., McMahon, Martin, Bosenberg, Marcus

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RAS Transformation Requires CUX1-Dependent Repair of Oxidative DNA Damage mā Ramdzan, Zubaidah M., Vadnais, Charles, Pal, Ranjana, Vandal, Guillaume, Cadieux, Chantal, Leduy, Lam, Davoudi, Sayeh, Hulea, Laura, Yao, Lu, Karnezis, Anthony N., Paquet, Marilène, Dankort, David, Nepveu, Alain

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β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas mā Damsky, William E., Curley, David P., Santhanakrishnan, Manjula, Rosenbaum, Lara E., Platt, James T., Gould Rothberg, Bonnie E., Taketo, Makoto M., Dankort, David, Rimm, David L., McMahon, Martin, Bosenberg, Marcus

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Abrogation of BRAF(V600E)-induced senescence by PI3K pathway activation contributes to melanomagenesis mā Vredeveld, Liesbeth C.W., Possik, Patricia A., Smit, Marjon A., Meissl, Katrin, Michaloglou, Chrysiis, Horlings, Hugo M., Ajouaou, Abderrahim, Kortman, Pim C., Dankort, David, McMahon, Martin, Mooi, Wolter J., Peeper, Daniel S.

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B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer mā Wang, Jingqiang, Kobayashi, Takashi, Floc'h, Nicolas, Kinkade, Carolyn Waugh, Aytes, Alvaro, Dankort, David, Lefebvre, Celine, Mitrofanova, Antonina, Cardiff, Robert D., McMahon, Martin, Califano, Andrea, Shen, Michael M., Abate-Shen, Cory

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A Central Role for RAF→MEK→ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma. mā Collisson, Eric A., Trejo, Christy, Silva, Jillian, Gu, Shenda, Korkola, James E., Heiser, Laura, Charles, Roch-Philippe, Rabinovich, Brian A., Hann, Byron, Dankort, David, Spellman, Paul T., Phillips, Wayne, Gray, Joe W., McMahon, Martin

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mTORC1 activation blocks Braf(V600E)-induced growth-arrest, but is insufficient for melanoma formation mā Damsky, William, Micevic, Goran, Meeth, Katrina, Muthusamy, Viswanathan, Curley, David P., Santhankrishnan, Manjula, Erdelyi, Ildiko, Platt, James T., Huang, Laura, Theodosakis, Nicholas, Zaidi, M. Raza, Tighe, Scott, Davies, Michael A., Dankort, David, McMahon, Martin, Merlino, Glenn, Bardeesy, Nabeel, Bosenberg, Marcus

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Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses mā Huang, Fan, Gonçalves, Christophe, Bartish, Margarita, Rémy-Sarrazin, Joelle, Issa, Mark E., Cordeiro, Brendan, Guo, Qianyu, Emond, Audrey, Attias, Mikhael, Yang, William, Plourde, Dany, Su, Jie, Gimeno, Marina Godoy, Zhan, Yao, Galán, Alba, Rzymski, Tomasz, Mazan, Milena, Masiejczyk, Magdalena, Faber, Jacek, Khoury, Elie, Benoit, Alexandre, Gagnon, Natascha, Dankort, David, Journe, Fabrice, Ghanem, Ghanem E., Krawczyk, Connie M., Saragovi, H. Uri, Piccirillo, Ciriaco A., Sonenberg, Nahum, Topisirovic, Ivan, Rudd, Christopher E., Miller, Wilson H., del Rincón, Sonia V.

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