Risultati della ricerca - Daniel T. Starczynowski

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  1. 1
    IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies

    IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies di Joshua Bennett, Daniel T. Starczynowski

    Pubblicazione 2021
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  2. 2
    IRAK signalling in cancer

    IRAK signalling in cancer di Garrett W. Rhyasen, Daniel T. Starczynowski

    Pubblicazione 2014
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  3. 3
    Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS

    Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS di Jennifer J. Trowbridge, Daniel T. Starczynowski

    Pubblicazione 2021
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  4. 4
    Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease

    Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease di Radhika Rawat, Daniel T. Starczynowski, Panagiotis Ntziachristos

    Pubblicazione 2019
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  5. 5
    Chronic immune response dysregulation in MDS pathogenesis

    Chronic immune response dysregulation in MDS pathogenesis di Laura Barreyro, Timothy M. Chlon, Daniel T. Starczynowski

    Pubblicazione 2018
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  6. 6
    An MDS xenograft model utilizing a patient-derived cell line

    An MDS xenograft model utilizing a patient-derived cell line di Garrett W. Rhyasen, Mark Wunderlich, Kaoru Tohyama, Guillermo Garcia‐Manero, James C. Mulloy, Daniel T. Starczynowski

    Pubblicazione 2013
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  7. 7
    Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets

    Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets di Tiansu Wang, Allison R. Pine, Andriana G. Kotini, Han Yuan, Lee Zamparo, Daniel T. Starczynowski, Christina Leslie, Eirini P. Papapetrou

    Pubblicazione 2021
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  8. 8
    MicroRNA-146a disrupts hematopoietic differentiation and survival

    MicroRNA-146a disrupts hematopoietic differentiation and survival di Daniel T. Starczynowski, Florian Kuchenbauer, Joanna Węgrzyn, A. MAUREEN ROUHI, Oleh I. Petriv, Carl L. Hansen, R. Keith Humphries, Aly Karsan

    Pubblicazione 2010
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  9. 9
    Research and clinical updates on IRAK4 and its roles in inflammation and malignancy: themes and highlights from the 1st symposium on IRAK4 in cancer

    Research and clinical updates on IRAK4 and its roles in inflammation and malignancy: themes and highlights from the 1st symposium on IRAK4 in cancer di Guillermo Garcia‐Manero, Uwe Platzbecker, Kian‐Huat Lim, Grzegorz S. Nowakowski, Omar Abdel‐Wahab, Hagop M. Kantarjian, Amit Verma, Daniel T. Starczynowski

    Pubblicazione 2024
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  10. 10
    Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes

    Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes di Irene Gañán‐Gómez, Yue Wei, Daniel T. Starczynowski, Simona Colla, Hui Yang, Mónica Cabrero, Zach Bohannan, Amit Verma, Ulrich Steidl, Guillermo Garcia‐Manero

    Pubblicazione 2015
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  11. 11
    Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs

    Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs di Tomoya Muto, Callum S. Walker, Kwangmin Choi, Kathleen Hueneman, Molly A. Smith, Zartash Gul, Guillermo Garcia‐Manero, Averil Ma, Yi Zheng, Daniel T. Starczynowski

    Pubblicazione 2020
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  12. 12
    TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

    TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer di Daniel T. Starczynowski, William W. Lockwood, Sophie Deléhouzée, Raj Chari, Joanna Węgrzyn, Megan Fuller, Ming‐Sound Tsao, Stephen Lam, Adi F. Gazdar, Wan L. Lam, Aly Karsan

    Pubblicazione 2011
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  13. 13
    High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival

    High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predict... di Daniel T. Starczynowski, Suzanne Vercauteren, Adèle Telenius, Sandy Sung, Kaoru Tohyama, Angela Brooks‐Wilson, John J. Spinelli, Connie J. Eaves, Allen Eaves, Douglas E. Horsman, Wan L. Lam, Aly Karsan

    Pubblicazione 2008
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  14. 14
    A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes

    A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes di Jing Fang, Xiaona Liu, Lyndsey Bolanos, Brenden Barker, Carmela Rigolino, Agostino Cortelezzi, Esther Natalie Olíva, Maria Cuzzola, H. Leighton Grimes, Celia Fontanillo, Kakajan Komurov, Kyle J. MacBeth, Daniel T. Starczynowski

    Pubblicazione 2016
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  15. 15
    Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis

    Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis di Fukun Guo, Shiwu Zhang, Matthew W. Grogg, José A. Cancelas, Melinda E. Varney, Daniel T. Starczynowski, Wei Du, Jun‐Qi Yang, Wei Liu, George Thomas, Sara C. Kozma, Qingsong Pang, Yi Zheng

    Pubblicazione 2013
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  16. 16
    Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia

    Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia di Timothy M. Chlon, Emily Stepanchick, Courtney E. Hershberger, Noah J. Daniels, Kathleen Hueneman, Ashley Kuenzi Davis, Kwangmin Choi, Yi Zheng, Carmelo Gurnari, Torsten Haferlach, Richard A. Padgett, Jaroslaw P. Maciejewski, Daniel T. Starczynowski

    Pubblicazione 2021
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  17. 17
    Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations

    Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations di Daniel T. Starczynowski, Ryan D. Morin, Andrew McPherson, Jeff Y. L. Lam, Raj Chari, Joanna Węgrzyn, Florian Kuchenbauer, Martin Hirst, Kaoru Tohyama, R. Keith Humphries, Wan L. Lam, Marco A. Marra, Aly Karsan

    Pubblicazione 2010
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  18. 18
    Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network

    Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network di Jing Fang, Brenden Barker, Lyndsey Bolanos, Xiaona Liu, Andrés Jerez, Hideki Makishima, Susanne Christie, Xiaoting Chen, Dinesh S. Rao, H. Leighton Grimes, Kakajan Komurov, Matthew T. Weirauch, José A. Cancelas, Jaroslaw P. Maciejewski, Daniel T. Starczynowski

    Pubblicazione 2014
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  19. 19
    Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1

    Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1 di Jing Fang, Garrett W. Rhyasen, Lyndsey Bolanos, C. Rasch, Melinda E. Varney, Mark Wunderlich, Susumu Goyama, Gerrit Jansen, Jacqueline Cloos, Carmela Rigolino, Agostino Cortelezzi, James C. Mulloy, Esther N. Oliva, Maria Cuzzola, Daniel T. Starczynowski

    Pubblicazione 2012
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  20. 20
    TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis

    TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis di Jing Fang, Tomoya Muto, Maria Kleppe, Lyndsey Bolanos, Kathleen Hueneman, Callum S. Walker, Leesa Sampson, Ashley M. Wellendorf, Kashish Chetal, Kwangmin Choi, Nathan Salomonis, Yongwon Choi, Yi Zheng, José A. Cancelas, Ross L. Levine, Daniel T. Starczynowski

    Pubblicazione 2018
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