Torthaí cuardaigh - Daniel T. Starczynowski

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  1. 1
    IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies

    IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies de réir Joshua Bennett, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2021
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  2. 2
    IRAK signalling in cancer

    IRAK signalling in cancer de réir Garrett W. Rhyasen, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2014
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  3. 3
    Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS

    Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS de réir Jennifer J. Trowbridge, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2021
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  4. 4
    Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease

    Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease de réir Radhika Rawat, Daniel T. Starczynowski, Panagiotis Ntziachristos

    Foilsithe / Cruthaithe 2019
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  5. 5
    Chronic immune response dysregulation in MDS pathogenesis

    Chronic immune response dysregulation in MDS pathogenesis de réir Laura Barreyro, Timothy M. Chlon, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2018
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  6. 6
    An MDS xenograft model utilizing a patient-derived cell line

    An MDS xenograft model utilizing a patient-derived cell line de réir Garrett W. Rhyasen, Mark Wunderlich, Kaoru Tohyama, Guillermo Garcia‐Manero, James C. Mulloy, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2013
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  7. 7
    Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets

    Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets de réir Tiansu Wang, Allison R. Pine, Andriana G. Kotini, Han Yuan, Lee Zamparo, Daniel T. Starczynowski, Christina Leslie, Eirini P. Papapetrou

    Foilsithe / Cruthaithe 2021
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  8. 8
    MicroRNA-146a disrupts hematopoietic differentiation and survival

    MicroRNA-146a disrupts hematopoietic differentiation and survival de réir Daniel T. Starczynowski, Florian Kuchenbauer, Joanna Węgrzyn, A. MAUREEN ROUHI, Oleh I. Petriv, Carl L. Hansen, R. Keith Humphries, Aly Karsan

    Foilsithe / Cruthaithe 2010
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  9. 9
    Research and clinical updates on IRAK4 and its roles in inflammation and malignancy: themes and highlights from the 1st symposium on IRAK4 in cancer

    Research and clinical updates on IRAK4 and its roles in inflammation and malignancy: themes and highlights from the 1st symposium on IRAK4 in cancer de réir Guillermo Garcia‐Manero, Uwe Platzbecker, Kian‐Huat Lim, Grzegorz S. Nowakowski, Omar Abdel‐Wahab, Hagop M. Kantarjian, Amit Verma, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2024
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  10. 10
    Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes

    Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes de réir Irene Gañán‐Gómez, Yue Wei, Daniel T. Starczynowski, Simona Colla, Hui Yang, Mónica Cabrero, Zach Bohannan, Amit Verma, Ulrich Steidl, Guillermo Garcia‐Manero

    Foilsithe / Cruthaithe 2015
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  11. 11
    Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs

    Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs de réir Tomoya Muto, Callum S. Walker, Kwangmin Choi, Kathleen Hueneman, Molly A. Smith, Zartash Gul, Guillermo Garcia‐Manero, Averil Ma, Yi Zheng, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2020
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  12. 12
    TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

    TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer de réir Daniel T. Starczynowski, William W. Lockwood, Sophie Deléhouzée, Raj Chari, Joanna Węgrzyn, Megan Fuller, Ming‐Sound Tsao, Stephen Lam, Adi F. Gazdar, Wan L. Lam, Aly Karsan

    Foilsithe / Cruthaithe 2011
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  13. 13
    High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival

    High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predict... de réir Daniel T. Starczynowski, Suzanne Vercauteren, Adèle Telenius, Sandy Sung, Kaoru Tohyama, Angela Brooks‐Wilson, John J. Spinelli, Connie J. Eaves, Allen Eaves, Douglas E. Horsman, Wan L. Lam, Aly Karsan

    Foilsithe / Cruthaithe 2008
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  14. 14
    A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes

    A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes de réir Jing Fang, Xiaona Liu, Lyndsey Bolanos, Brenden Barker, Carmela Rigolino, Agostino Cortelezzi, Esther Natalie Olíva, Maria Cuzzola, H. Leighton Grimes, Celia Fontanillo, Kakajan Komurov, Kyle J. MacBeth, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2016
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  15. 15
    Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis

    Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis de réir Fukun Guo, Shiwu Zhang, Matthew W. Grogg, José A. Cancelas, Melinda E. Varney, Daniel T. Starczynowski, Wei Du, Jun‐Qi Yang, Wei Liu, George Thomas, Sara C. Kozma, Qingsong Pang, Yi Zheng

    Foilsithe / Cruthaithe 2013
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  16. 16
    Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia

    Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia de réir Timothy M. Chlon, Emily Stepanchick, Courtney E. Hershberger, Noah J. Daniels, Kathleen Hueneman, Ashley Kuenzi Davis, Kwangmin Choi, Yi Zheng, Carmelo Gurnari, Torsten Haferlach, Richard A. Padgett, Jaroslaw P. Maciejewski, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2021
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  17. 17
    Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations

    Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations de réir Daniel T. Starczynowski, Ryan D. Morin, Andrew McPherson, Jeff Y. L. Lam, Raj Chari, Joanna Węgrzyn, Florian Kuchenbauer, Martin Hirst, Kaoru Tohyama, R. Keith Humphries, Wan L. Lam, Marco A. Marra, Aly Karsan

    Foilsithe / Cruthaithe 2010
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  18. 18
    Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network

    Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network de réir Jing Fang, Brenden Barker, Lyndsey Bolanos, Xiaona Liu, Andrés Jerez, Hideki Makishima, Susanne Christie, Xiaoting Chen, Dinesh S. Rao, H. Leighton Grimes, Kakajan Komurov, Matthew T. Weirauch, José A. Cancelas, Jaroslaw P. Maciejewski, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2014
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  19. 19
    Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1

    Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1 de réir Jing Fang, Garrett W. Rhyasen, Lyndsey Bolanos, C. Rasch, Melinda E. Varney, Mark Wunderlich, Susumu Goyama, Gerrit Jansen, Jacqueline Cloos, Carmela Rigolino, Agostino Cortelezzi, James C. Mulloy, Esther N. Oliva, Maria Cuzzola, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2012
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  20. 20
    TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis

    TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis de réir Jing Fang, Tomoya Muto, Maria Kleppe, Lyndsey Bolanos, Kathleen Hueneman, Callum S. Walker, Leesa Sampson, Ashley M. Wellendorf, Kashish Chetal, Kwangmin Choi, Nathan Salomonis, Yongwon Choi, Yi Zheng, José A. Cancelas, Ross L. Levine, Daniel T. Starczynowski

    Foilsithe / Cruthaithe 2018
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