Søgeresultater - Daniel Nettersheim

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  1. 1
    Molecular and epigenetic pathogenesis of germ cell tumors

    Molecular and epigenetic pathogenesis of germ cell tumors af Melanie Müller, Margaretha A. Skowron, Peter Albers, Daniel Nettersheim

    Udgivet 2020
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  2. 2
    TCam-2 but not JKT-1 cells resemble seminoma in cell culture

    TCam-2 but not JKT-1 cells resemble seminoma in cell culture af D. Eckert, Daniel Nettersheim, Lukas C. Heukamp, Sohei Kitazawa, Katharina Biermann, Hubert Schorle

    Udgivet 2007
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  3. 3
    N6‐Methyladenosine detected in <scp>RNA</scp> of testicular germ cell tumors is controlled by <scp>METTL</scp>3, <scp>ALKBH</scp>5, <scp>YTHDC</scp>1/F1/F2, and <scp>HNRNPC</scp> as writers, erasers, and readers

    N6‐Methyladenosine detected in <scp>RNA</scp> of testicular germ cell tumors is controlled by <scp>METTL</scp>3, <scp>ALKBH</scp>5, <scp>YTHDC</scp>1/F1/F2, and <scp>HNRNPC</scp> a... af Daniel Nettersheim, Daniel R. Berger, Sina Jostes, Glen Kristiansen, G. Lochnit, Hubert Schorle

    Udgivet 2019
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  4. 4
    NANOG promoter methylation and expression correlation during normal and malignant human germ cell development

    NANOG promoter methylation and expression correlation during normal and malignant human germ cell development af Daniel Nettersheim, Katharina Biermann, Ad Gillis, Klaus Steger, Leendert H. J. Looijenga, Hubert Schorle

    Udgivet 2011
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  5. 5
    SOX2 is essential for <i>in vivo</i> reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate

    SOX2 is essential for <i>in vivo</i> reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate af Daniel Nettersheim, Alena Heimsoeth, Sina Jostes, Simon Schneider, Martin Fellermeyer, Andrea Hofmann, Hubert Schorle

    Udgivet 2016
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  6. 6
    Unique and redundant roles of SOX2 and SOX17 in regulating the germ cell tumor fate

    Unique and redundant roles of SOX2 and SOX17 in regulating the germ cell tumor fate af Sina Jostes, Martin Fellermeyer, Lena Arévalo, Gina Esther Merges, Glen Kristiansen, Daniel Nettersheim, Hubert Schorle

    Udgivet 2019
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  7. 7
    A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment

    A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment af Daniel Nettersheim, Sina Jostes, Martin Fabry, Friedemann Honecker, Valérie Schumacher, Jutta Kirfel, Glen Kristiansen, Hubert Schorle

    Udgivet 2016
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  8. 8
    The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas

    The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas af Daniel Nettersheim, I Arndt, Rakesh Sharma, Stefanie Riesenberg, Sina Jostes, Simon Schneider, Michael Hölzel, Glen Kristiansen, Hubert Schorle

    Udgivet 2016
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  9. 9
    The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours<i>in vitro</i>and<i>in vivo</i>

    The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours<i>in vitro</i>and<i>in vivo</i> af Sina Jostes, Daniel Nettersheim, Martin Fellermeyer, Simon Schneider, François Hafezi, Friedemann Honecker, Valérie Schumacher, Matthias Geyer, Glen Kristiansen, Hubert Schorle

    Udgivet 2016
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  10. 10
    BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma

    BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma af Daniel Nettersheim, Sina Jostes, Rakesh Sharma, Simon Schneider, Andrea Hofmann, Humberto J. Ferreira, Per Hoffmann, Glen Kristiansen, Manel Esteller, Hubert Schorle

    Udgivet 2015
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  11. 11
    Expression of BLIMP1/PRMT5and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors

    Expression of BLIMP1/PRMT5and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors af Dawid Eckert, Katharina Biermann, Daniel Nettersheim, Ad Gillis, Klaus Steger, Hans‐Martin Jäck, Annette Müller, Leendert H. J. Looijenga, Hubert Schorle

    Udgivet 2008
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  12. 12
    Analysis of TET Expression/Activity and 5mC Oxidation during Normal and Malignant Germ Cell Development

    Analysis of TET Expression/Activity and 5mC Oxidation during Normal and Malignant Germ Cell Development af Daniel Nettersheim, Lukas C. Heukamp, Florian Fronhoffs, Marc J Grewe, Natalie Haas, Anke Waha, Friedemann Honecker, Andreas Waha, Glen Kristiansen, Hubert Schorle

    Udgivet 2013
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  13. 13
    Transcription Factor TFAP2C Regulates Major Programs Required for Murine Fetal Germ Cell Maintenance and Haploinsufficiency Predisposes to Teratomas in Male Mice

    Transcription Factor TFAP2C Regulates Major Programs Required for Murine Fetal Germ Cell Maintenance and Haploinsufficiency Predisposes to Teratomas in Male Mice af Jana Schemmer, Marcos J. Araúzo‐Bravo, Natalie Haas, Sabine Schäfer, Susanne N. Weber, Astrid Becker, Dawid Eckert, Andreas Zimmer, Daniel Nettersheim, Hubert Schorle

    Udgivet 2013
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  14. 14
    Reference Gene Validation for RT-qPCR, a Note on Different Available Software Packages

    Reference Gene Validation for RT-qPCR, a Note on Different Available Software Packages af Ward De Spiegelaere, Jutta Dern-Wieloch, Roswitha Weigel, Valérie Schumacher, Hubert Schorle, Daniel Nettersheim, Martin Bergmann, Ralph Brehm, Sabine Kliesch, Linos Vandekerckhove, Cornelia Fink

    Udgivet 2015
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  15. 15
    CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms

    CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms af Margaretha A. Skowron, Marieke Vermeulen, Anna Winkelhausen, Teresa K. Becker, Felix Bremmer, Patrick Petzsch, Stefan Schönberger, Gabriele Calaminus, Karl Köhrer, Peter Albers, Daniel Nettersheim

    Udgivet 2020
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  16. 16
    Critical Function of AP-2gamma/TCFAP2C in Mouse Embryonic Germ Cell Maintenance1

    Critical Function of AP-2gamma/TCFAP2C in Mouse Embryonic Germ Cell Maintenance1 af Susanne N. Weber, Dawid Eckert, Daniel Nettersheim, Ad Gillis, Sabine Schäfer, Peter Kuckenberg, Julia Ehlermann, Uwe Werling, Katharina Biermann, Leendert H. J. Looijenga, Hubert Schorle

    Udgivet 2009
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  17. 17
    Re-visiting the Protamine-2 locus: deletion, but not haploinsufficiency, renders male mice infertile

    Re-visiting the Protamine-2 locus: deletion, but not haploinsufficiency, renders male mice infertile af Simon Schneider, Melanie Balbach, Jan F. Jikeli, Daniela Fietz, Daniel Nettersheim, Sina Jostes, Rovenna Schmidt, Monika Kressin, Martin Bergmann, Dagmar Wachten, Klaus Steger, Hubert Schorle

    Udgivet 2016
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  18. 18
    The detection of isochromosome i(12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real‐time polymerase chain reaction

    The detection of isochromosome i(12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real‐time polymerase chain reactio... af Alexander Fichtner, Annika Richter, Simon Filmar, Nadine T. Gaisa, Stefan Schweyer, Henning Reis, Daniel Nettersheim, Christoph Oing, Fabian A. Gayer, Andreas Leha, Stefan Küffer, Philipp Ströbel, Silke Kaulfuß, Felix Bremmer

    Udgivet 2020
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  19. 19
    Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets

    Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of t... af Felix Bremmer, Pailin Pongratanakul, Margaretha A. Skowron, Yue Che, Annika Richter, Stefan Küffer, Kirsten Reuter‐Jessen, Hanibal Bohnenberger, Stella Pauls, Catena Kresbach, Ulrich Schüller, Kai Stühler, Philipp Ströbel, Peter Albers, Daniel Nettersheim

    Udgivet 2023
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  20. 20
    The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors

    The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors af Vera Miranda‐Gonçalves, João Lobo, Catarina Guimarães‐Teixeira, Daniela Barros‐Silva, Rita de Cássia Avellaneda Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Christoph Oing, Friedemann Honecker, Daniel Nettersheim, Leendert H. J. Looijenga, Rui Henrique, Cármen Jerónimo

    Udgivet 2021
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