Risultati della ricerca - Daniel Kümmel

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  1. 1
    Structure of membrane tethers and their role in fusion

    Structure of membrane tethers and their role in fusion di Christian Ungermann, Daniel Kümmel

    Pubblicazione 2019
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  2. 2
    Insights into the role of the membranes in Rab GTPase regulation

    Insights into the role of the membranes in Rab GTPase regulation di Stephan Wilmes, Daniel Kümmel

    Pubblicazione 2023
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  3. 3
    A guanine nucleotide exchange factor (GEF) limits Rab GTPase–driven membrane fusion

    A guanine nucleotide exchange factor (GEF) limits Rab GTPase–driven membrane fusion di Lars Langemeyer, Angela Perz, Daniel Kümmel, Christian Ungermann

    Pubblicazione 2017
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  4. 4
    Vectors for co-expression of an unrestricted number of proteins

    Vectors for co-expression of an unrestricted number of proteins di Christoph Scheich, Daniel Kümmel, D. Soumailakakis, Udo Heinemann, Konrad Büssow

    Pubblicazione 2007
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  5. 5
    Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure

    Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure di Jieqiong Gao, Lars Langemeyer, Daniel Kümmel, Fulvio Reggiori, Christian Ungermann

    Pubblicazione 2018
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  6. 6
    A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

    A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids di Peter Gollwitzer, Nina Grützmacher, Sabine Wilhelm, Daniel Kümmel, Constantinos Demetriades

    Pubblicazione 2022
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  7. 7
    Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code

    Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code di Eric Herrmann, Lars Langemeyer, Kathrin Auffarth, Christian Ungermann, Daniel Kümmel

    Pubblicazione 2023
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  8. 8
    The Habc Domain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion

    The Habc Domain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion di Anna Lürick, Anne Kuhlee, Cornelia Bröcker, Daniel Kümmel, Stefan Raunser, Christian Ungermann

    Pubblicazione 2015
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  9. 9
    A Half-Zippered SNARE Complex Represents a Functional Intermediate in Membrane Fusion

    A Half-Zippered SNARE Complex Represents a Functional Intermediate in Membrane Fusion di Feng Li, Daniel Kümmel, Jeff Coleman, Karin M. Reinisch, James E. Rothman, Frédéric Pincet

    Pubblicazione 2014
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  10. 10
    Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1

    Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1 di Stephan Kiontke, Lars Langemeyer, Anne Kuhlee, Saskia Schuback, Stefan Raunser, Christian Ungermann, Daniel Kümmel

    Pubblicazione 2017
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  11. 11
    Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo

    Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo di Richard W. Cho, Daniel Kümmel, Feng Li, Stephanie Wood Baguley, Jeff Coleman, James E. Rothman, J. Troy Littleton

    Pubblicazione 2014
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  12. 12
    Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation

    Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation di Ann-Christin Borchers, Maren Janz, Jan-Hannes Schäfer, Arne Moeller, Daniel Kümmel, Achim Paululat, Christian Ungermann, Lars Langemeyer

    Pubblicazione 2023
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  13. 13
    Complexin cross-links prefusion SNAREs into a zigzag array

    Complexin cross-links prefusion SNAREs into a zigzag array di Daniel Kümmel, Shyam S. Krishnakumar, Daniel T Radoff, Feng Li, Claudio G. Giraudo, Frédéric Pincet, James E. Rothman, Karin M. Reinisch

    Pubblicazione 2011
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  14. 14
    A conserved and regulated mechanism drives endosomal Rab transition

    A conserved and regulated mechanism drives endosomal Rab transition di Lars Langemeyer, Ann-Christin Borchers, Eric Herrmann, Nadia Füllbrunn, Yaping Han, Angela Perz, Kathrin Auffarth, Daniel Kümmel, Christian Ungermann

    Pubblicazione 2020
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  15. 15
    Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate

    Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate di Xudong Wu, Michael J. Bradley, Yiying Cai, Daniel Kümmel, Enrique M. De La Cruz, Francis A. Barr, Karin M. Reinisch

    Pubblicazione 2011
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  16. 16
    The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p

    The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p di David Shen, Hua Yuan, Alex H. Hutagalung, Avani Verma, Daniel Kümmel, Xudong Wu, Karin M. Reinisch, James A. McNew, Peter Novick

    Pubblicazione 2013
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  17. 17
    A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion

    A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion di Shyam S. Krishnakumar, Daniel T Radoff, Daniel Kümmel, Claudio G. Giraudo, Feng Li, Lavan Khandan, Stephanie Wood Baguley, Jeff Coleman, Karin M. Reinisch, Frédéric Pincet, James E. Rothman

    Pubblicazione 2011
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  18. 18
    Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery

    Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery di Dmitry Shvarev, Jannis Schoppe, Caroline König, Angela Perz, Nadia Füllbrunn, Stephan Kiontke, Lars Langemeyer, Dovile Januliene, Kilian Schnelle, Daniel Kümmel, Florian Fröhlich, Arne Moeller, Christian Ungermann

    Pubblicazione 2022
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  19. 19
    Comparison of the functional and structural characteristics of rare <i>TSC2</i> variants with clinical and genetic findings

    Comparison of the functional and structural characteristics of rare <i>TSC2</i> variants with clinical and genetic findings di Luiz Gustavo Dufner‐Almeida, Santoesha Nanhoe, Andrea Zonta, Mitra Hosseinzadeh, Regina Kom‐Gortat, Peter Elfferich, Gerben Schaaf, Annegien Kenter, Daniel Kümmel, Nicola Migone, Sue Povey, Rosemary Ekong, Mark Nellist

    Pubblicazione 2019
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  20. 20
    RalGAP complexes control secretion and primary cilia in pancreatic disease

    RalGAP complexes control secretion and primary cilia in pancreatic disease di Lisa Helene Apken, Helmut Barz, Stephanie Beel, Esther Michalke, René Rasche, Archana Verma, Andrea Ricker, Harald Nüsse, Jürgen Klingauf, Kornelius Kerl, Eva Wardelmann, Daniel Kümmel, Konrad Steinestel, Zoltán Pethő, Michael Meisterernst, Andrea Oeckinghaus

    Pubblicazione 2025
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