Resultats de la cerca - Daniel Kümmel

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  1. 1
    Structure of membrane tethers and their role in fusion

    Structure of membrane tethers and their role in fusion per Christian Ungermann, Daniel Kümmel

    Publicat 2019
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  2. 2
    Insights into the role of the membranes in Rab GTPase regulation

    Insights into the role of the membranes in Rab GTPase regulation per Stephan Wilmes, Daniel Kümmel

    Publicat 2023
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  3. 3
    A guanine nucleotide exchange factor (GEF) limits Rab GTPase–driven membrane fusion

    A guanine nucleotide exchange factor (GEF) limits Rab GTPase–driven membrane fusion per Lars Langemeyer, Angela Perz, Daniel Kümmel, Christian Ungermann

    Publicat 2017
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  4. 4
    Vectors for co-expression of an unrestricted number of proteins

    Vectors for co-expression of an unrestricted number of proteins per Christoph Scheich, Daniel Kümmel, D. Soumailakakis, Udo Heinemann, Konrad Büssow

    Publicat 2007
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  5. 5
    Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure

    Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure per Jieqiong Gao, Lars Langemeyer, Daniel Kümmel, Fulvio Reggiori, Christian Ungermann

    Publicat 2018
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  6. 6
    A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

    A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids per Peter Gollwitzer, Nina Grützmacher, Sabine Wilhelm, Daniel Kümmel, Constantinos Demetriades

    Publicat 2022
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  7. 7
    Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code

    Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code per Eric Herrmann, Lars Langemeyer, Kathrin Auffarth, Christian Ungermann, Daniel Kümmel

    Publicat 2023
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  8. 8
    The Habc Domain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion

    The Habc Domain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion per Anna Lürick, Anne Kuhlee, Cornelia Bröcker, Daniel Kümmel, Stefan Raunser, Christian Ungermann

    Publicat 2015
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  9. 9
    A Half-Zippered SNARE Complex Represents a Functional Intermediate in Membrane Fusion

    A Half-Zippered SNARE Complex Represents a Functional Intermediate in Membrane Fusion per Feng Li, Daniel Kümmel, Jeff Coleman, Karin M. Reinisch, James E. Rothman, Frédéric Pincet

    Publicat 2014
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  10. 10
    Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1

    Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1 per Stephan Kiontke, Lars Langemeyer, Anne Kuhlee, Saskia Schuback, Stefan Raunser, Christian Ungermann, Daniel Kümmel

    Publicat 2017
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  11. 11
    Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo

    Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo per Richard W. Cho, Daniel Kümmel, Feng Li, Stephanie Wood Baguley, Jeff Coleman, James E. Rothman, J. Troy Littleton

    Publicat 2014
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  12. 12
    Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation

    Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation per Ann-Christin Borchers, Maren Janz, Jan-Hannes Schäfer, Arne Moeller, Daniel Kümmel, Achim Paululat, Christian Ungermann, Lars Langemeyer

    Publicat 2023
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  13. 13
    Complexin cross-links prefusion SNAREs into a zigzag array

    Complexin cross-links prefusion SNAREs into a zigzag array per Daniel Kümmel, Shyam S. Krishnakumar, Daniel T Radoff, Feng Li, Claudio G. Giraudo, Frédéric Pincet, James E. Rothman, Karin M. Reinisch

    Publicat 2011
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  14. 14
    A conserved and regulated mechanism drives endosomal Rab transition

    A conserved and regulated mechanism drives endosomal Rab transition per Lars Langemeyer, Ann-Christin Borchers, Eric Herrmann, Nadia Füllbrunn, Yaping Han, Angela Perz, Kathrin Auffarth, Daniel Kümmel, Christian Ungermann

    Publicat 2020
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  15. 15
    Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate

    Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate per Xudong Wu, Michael J. Bradley, Yiying Cai, Daniel Kümmel, Enrique M. De La Cruz, Francis A. Barr, Karin M. Reinisch

    Publicat 2011
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  16. 16
    The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p

    The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p per David Shen, Hua Yuan, Alex H. Hutagalung, Avani Verma, Daniel Kümmel, Xudong Wu, Karin M. Reinisch, James A. McNew, Peter Novick

    Publicat 2013
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  17. 17
    A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion

    A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion per Shyam S. Krishnakumar, Daniel T Radoff, Daniel Kümmel, Claudio G. Giraudo, Feng Li, Lavan Khandan, Stephanie Wood Baguley, Jeff Coleman, Karin M. Reinisch, Frédéric Pincet, James E. Rothman

    Publicat 2011
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  18. 18
    Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery

    Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery per Dmitry Shvarev, Jannis Schoppe, Caroline König, Angela Perz, Nadia Füllbrunn, Stephan Kiontke, Lars Langemeyer, Dovile Januliene, Kilian Schnelle, Daniel Kümmel, Florian Fröhlich, Arne Moeller, Christian Ungermann

    Publicat 2022
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  19. 19
    Comparison of the functional and structural characteristics of rare <i>TSC2</i> variants with clinical and genetic findings

    Comparison of the functional and structural characteristics of rare <i>TSC2</i> variants with clinical and genetic findings per Luiz Gustavo Dufner‐Almeida, Santoesha Nanhoe, Andrea Zonta, Mitra Hosseinzadeh, Regina Kom‐Gortat, Peter Elfferich, Gerben Schaaf, Annegien Kenter, Daniel Kümmel, Nicola Migone, Sue Povey, Rosemary Ekong, Mark Nellist

    Publicat 2019
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  20. 20
    RalGAP complexes control secretion and primary cilia in pancreatic disease

    RalGAP complexes control secretion and primary cilia in pancreatic disease per Lisa Helene Apken, Helmut Barz, Stephanie Beel, Esther Michalke, René Rasche, Archana Verma, Andrea Ricker, Harald Nüsse, Jürgen Klingauf, Kornelius Kerl, Eva Wardelmann, Daniel Kümmel, Konrad Steinestel, Zoltán Pethő, Michael Meisterernst, Andrea Oeckinghaus

    Publicat 2025
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