Search Results - Daniel D. Lam

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  1. 1
    Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria

    Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria by Kavaljit H. Chhabra, Jessica M. Adams, Brian Fagel, Daniel D. Lam, Nathan Qi, Marcelo Rubinstein, Malcolm J. Low

    Published 2015
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  2. 2
    Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors

    Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors by Daniel D. Lam, Magdalena J. Przydzial, Simon H. Ridley, Giles S.H. Yeo, Justin J. Rochford, Stephen O’Rahilly, Lora K. Heisler

    Published 2007
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  3. 3
    Brain Glucose Sensors Play a Significant Role in the Regulation of Pancreatic Glucose-Stimulated Insulin Secretion

    Brain Glucose Sensors Play a Significant Role in the Regulation of Pancreatic Glucose-Stimulated Insulin Secretion by Mayowa Osundiji, Daniel D. Lam, Jill Shaw, Chen-Yu Yueh, S. Pauliina Markkula, Paul Hurst, Carolina Colliva, Aldo Roda, Lora K. Heisler, Mark L. Evans

    Published 2011
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  4. 4
    Spatial enhancer activation influences inhibitory neuron identity during mouse embryonic development

    Spatial enhancer activation influences inhibitory neuron identity during mouse embryonic development by Elena Dvoretskova, May C. Ho, Volker Kittke, Florian Neuhaus, Ilaria Vitali, Daniel D. Lam, Irene Delgado, Chao Feng, Miguel Torres, Juliane Winkelmann, Christian Mayer

    Published 2024
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  5. 5
    High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons

    High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons by Thomas J.F. Nieland, David J. Logan, Jessica L. Saulnier, Daniel D. Lam, Caroline A. Johnson, David E. Root, Anne E. Carpenter, Bernardo L. Sabatini

    Published 2014
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  6. 6
    Partially Redundant Enhancers Cooperatively Maintain Mammalian Pomc Expression Above a Critical Functional Threshold

    Partially Redundant Enhancers Cooperatively Maintain Mammalian Pomc Expression Above a Critical Functional Threshold by Daniel D. Lam, Flávio S. J. de Souza, Sofía Nasif, Miho Yamashita, Rodrigo López‐Leal, Veronica Otero-Corchón, Kana Meece, Harini Sampath, Aaron J. Mercer, Sharon L. Wardlaw, Marcelo Rubinstein, Malcolm J. Low

    Published 2015
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  7. 7
    Recessive Mutations in the α3 (VI) Collagen Gene COL6A3 Cause Early-Onset Isolated Dystonia

    Recessive Mutations in the α3 (VI) Collagen Gene COL6A3 Cause Early-Onset Isolated Dystonia by Michael Zech, Daniel D. Lam, Ludmila Francescatto, Barbara Schormair, Aaro V. Salminen, Angela Jochim, Thomas Wieland, Peter Lichtner, Annette Peters, Christian Gieger, Hanns Lochmüller, Tim M. Strom, Bernhard Haslinger, Nicholas Katsanis, Juliane Winkelmann

    Published 2015
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  8. 8
    Cas9 activates the p53 pathway and selects for p53-inactivating mutations

    Cas9 activates the p53 pathway and selects for p53-inactivating mutations by Oana M. Enache, Verónica Rendo, Mai Abdusamad, Daniel D. Lam, Desiree Davison, Sangita Pal, Naomi Currimjee, Julian M. Hess, Sasha Pantel, Anwesha Nag, Aaron R. Thorner, John G. Doench, Francisca Vázquez, Rameen Beroukhim, Todd R. Golub, Uri Ben‐David

    Published 2020
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  9. 9
    Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways

    Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways by Ligang Zhou, Gregory M. Sutton, Justin J. Rochford, Robert K. Semple, Daniel D. Lam, Laura Oksanen, Zoë D. Thornton-Jones, Peter G. Clifton, Chen-Yu Yueh, Mark L. Evans, Rory J. McCrimmon, Joel K. Elmquist, Andrew A. Butler, Lora K. Heisler

    Published 2007
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  10. 10
    Leptin Does Not Directly Affect CNS Serotonin Neurons to Influence Appetite

    Leptin Does Not Directly Affect CNS Serotonin Neurons to Influence Appetite by Daniel D. Lam, Gina M. Leinninger, Gwendolyn W. Louis, Alastair S. Garfield, Oliver Marston, Rebecca L. Leshan, Erica L. Scheller, Lyndsay Christensen, José Donato, Jing Xia, Mark L. Evans, Carol F. Elias, Jeffrey W. Dalley, Denis Burdakov, Martin G. Myers, Lora K. Heisler

    Published 2011
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  11. 11
    Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism

    Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism by K. Ganesh Kumar, James L. Trevaskis, Daniel D. Lam, Gregory M. Sutton, Robert A. Koza, Vladimir N. Chouljenko, Konstantin G. Kousoulas, Pamela M. Rogers, Robert A. Kesterson, Marie S. Thearle, Anthony W. Ferrante, Randall L. Mynatt, Thomas P. Burris, Jesse Z. Dong, Heather Halem, Michael D. Culler, Lora K. Heisler, Jacqueline M. Stephens, Andrew A. Butler

    Published 2008
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  12. 12
    Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons

    Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons by Luke K. Burke, Barbora Doslikova, Giuseppe D’Agostino, Megan Greenwald-Yarnell, Teodora Georgescu, Raffaella Chianese, Pablo B. Martínez de Morentin, Emmanuel Ogunnowo-Bada, Céline Cansell, Lourdes Valencia-Torres, Alastair S. Garfield, John Apergis‐Schoute, Daniel D. Lam, John R. Speakman, Marcelo Rubinstein, Malcolm J. Low, Justin J. Rochford, Martin G. Myers, Mark L. Evans, Lora K. Heisler

    Published 2016
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  13. 13
    A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

    A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations by Lev Litichevskiy, Ryan Peckner, Jennifer G. Abelin, Jacob K. Asiedu, Amanda L. Creech, John F. Davis, Desiree Davison, Caitlin M. Dunning, Jarrett D. Egertson, Shawn B. Egri, Joshua Gould, Tak Ko, Sarah Johnson, David L. Lahr, Daniel D. Lam, Zihan Liu, Nicholas Lyons, Xiaodong Lü, Brendan MacLean, Alison E. Mungenast, Adam Officer, Ted Natoli, Malvina Papanastasiou, Jinal Patel, Vagisha Sharma, Courtney Toder, Andrew A. Tubelli, Jennie Z. Young, Steven A. Carr, Todd R. Golub, Aravind Subramanian, Michael J. MacCoss, Li‐Huei Tsai, Jacob D. Jaffe

    Published 2018
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  14. 14
    A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

    A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles by Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub

    Published 2017
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  15. 15
    A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

    A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles by Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Sarah Johnson, Nicholas Lyons, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Roger Hu, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Peyton Greenside, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub

    Published 2017
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