检索结果 - Daniel Conole

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  1. 1
    UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology

    UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology 由 Milon Mondal, Daniel Conole, Jaya Nautiyal, Edward W. Tate

    出版 2021
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  2. 2
    Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30

    Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30 由 Milon Mondal, Fangyuan Cao, Daniel Conole, Holger W. Auner, Edward W. Tate

    出版 2024
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  3. 3
    Non-Histone Protein Methylation: Biological Significance and Bioengineering Potential

    Non-Histone Protein Methylation: Biological Significance and Bioengineering Potential 由 Roberto Di Blasi, Oleg Blyuss, John F. Timms, Daniel Conole, Francesca Ceroni, Harry J. Whitwell

    出版 2021
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  4. 4
    Spatiotemporally resolved GPCR interactome uncovers unique mediators of receptor agonism

    Spatiotemporally resolved GPCR interactome uncovers unique mediators of receptor agonism 由 Maria M. Shchepinova, Rachel Richardson, Jack W. Houghton, Abigail R. Walker, Mohammed Safar, Daniel Conole, Aylin C. Hanyaloglu, Edward W. Tate

    出版 2025
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  5. 5
    Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs

    Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs 由 Rishi R. Shah, Elena De Vita, Preethi S. Sathyamurthi, Daniel Conole, Xinyue Zhang, Elliot Fellows, Eleanor R. Dickinson, Carlos Martinez Fleites, Markus A. Queisser, John D. Harling, Edward W. Tate

    出版 2024
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  6. 6
    Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles

    Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles 由 Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Daniel Conole, Adrian Blaser, Scott G. Franzblau, Christopher B. Cooper, Anna M. Upton, Manisha U. Lotlikar, William A. Denny, Brian D. Palmer

    出版 2018
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  7. 7
    Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

    Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline 由 Adrian Blaser, Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Daniel Conole, Scott G. Franzblau, Christopher B. Cooper, Anna M. Upton, Manisha U. Lotlikar, William A. Denny, Brian D. Palmer

    出版 2019
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  8. 8
    3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

    3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel 由 Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Adrian Blaser, Daniel Conole, Scott G. Franzblau, Manisha U. Lotlikar, Christopher B. Cooper, Anna M. Upton, William A. Denny, Brian D. Palmer

    出版 2019
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  9. 9
    6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis

    6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis 由 Amy S.T. Tong, Peter J. Choi, Adrian Blaser, Hamish S. Sutherland, Sophia K. Y. Tsang, Jérôme Guillemont, Magali Motte, Christopher B. Cooper, Koen Andries, Walter Van den Broeck, Scott G. Franzblau, Anna M. Upton, William A. Denny, Brian D. Palmer, Daniel Conole

    出版 2017
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  10. 10
    Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)

    Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs) 由 Qisi Zhang, Cyrille S. Kounde, Milon Mondal, Jake L. Greenfield, Jennifer R. Baker, Sergei Kotelnikov, Mikhail Ignatov, Christopher P. Tinworth, Leran Zhang, Daniel Conole, Elena De Vita, Dima Kozakov, Adam McCluskey, John D. Harling, Matthew J. Fuchter, Edward W. Tate

    出版 2022
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  11. 11
    Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer

    Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer 由 Bruno M. Simões, Angélica Santiago-Gómez, Chiara Chiodo, Tiago Moreira, Daniel Conole, S. Lovell, Denis Alférez, Rachel Eyre, Katherine Spence, Aida Sarmiento-Castro, Bertram Kohler, Ludivine Morisset, Marilena Lanzino, Sebastiano Andò, Elisabetta Marangoni, Andrew H. Sims, Edward W. Tate, Sacha J. Howell, Robert B. Clarke

    出版 2020
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