Søgeresultater - Dae‐Kee Kim

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  1. 1
    Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension

    Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension af Lü Long, Alexi Crosby, Xudong Yang, Mark Southwood, Paul D. Upton, Dae-Kee Kim, Nicholas W. Morrell

    Udgivet 2009
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  2. 2
    TGF-β Type I Receptor Kinase Inhibitor EW-7197 Suppresses Cholestatic Liver Fibrosis by Inhibiting HIF1α-Induced Epithelial Mesenchymal Transition

    TGF-β Type I Receptor Kinase Inhibitor EW-7197 Suppresses Cholestatic Liver Fibrosis by Inhibiting HIF1α-Induced Epithelial Mesenchymal Transition af Min‐Jin Kim, Sang-A Park, Chun Hwa Kim, So-Yeon Park, Jung‐Shin Kim, Dae‐Kee Kim, Jeong‐Seok Nam, Yhun Yhong Sheen

    Udgivet 2016
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    Artigo
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  3. 3
    Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells

    Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells af So‐Yeon Park, Min-Jin Kim, Sang-A Park, Jung‐Shin Kim, Kyung-Nan Min, Dae‐Kee Kim, Woosung Lim, Jeong‐Seok Nam, Yhun Yhong Sheen

    Udgivet 2015
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    Artigo
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  4. 4
    EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling

    EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling af Sang-A Park, Min-Jin Kim, So-Yeon Park, Jung-Shin Kim, Seonjoo Lee, Hyun Ae Woo, Dae-Kee Kim, Jeong‐Seok Nam, Yhun Yhong Sheen

    Udgivet 2014
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  5. 5
    Glia-dependent TGF-β signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis

    Glia-dependent TGF-β signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis af Jian Luo, Peggy P. Ho, Marion S. Buckwalter, Tiffany Hsu, Lowen Y. Lee, Hui Zhang, Dae‐Kee Kim, Seong‐Jin Kim, Sanjiv S. Gambhir, Lawrence Steinman, Tony Wyss‐Coray

    Udgivet 2007
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  6. 6
    Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-β signaling

    Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-β signaling af Sirichat Kaowinn, Jeonghyo Kim, Jaebeom Lee, Dong Hoon Shin, Chi-Dug Kang, Dae‐Kee Kim, Soojin Lee, Min Kyung Kang, Sang Seok Koh, Seong‐Jin Kim, Young-Hwa Chung

    Udgivet 2016
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  7. 7
    Discovery of <i>N</i>-((4-([1,2,4]Triazolo[1,5-<i>a</i>]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1<i>H</i>-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of TGF-β Type I Receptor Kinase as Cancer Immunotherapeutic/Antifibrotic Agent

    Discovery of <i>N</i>-((4-([1,2,4]Triazolo[1,5-<i>a</i>]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1<i>H</i>-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A Highly Potent, Selective... af Cheng Hua Jin, Maddeboina Krishnaiah, D. Sreenu, Vura Bala Subrahmanyam, Kota Sudhakar Rao, Hwa Jeong Lee, So‐Jung Park, Hyun‐Ju Park, Kiho Lee, Yhun Yhong Sheen, Dae‐Kee Kim

    Udgivet 2014
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  8. 8
    EW-7197, a Novel ALK-5 Kinase Inhibitor, Potently Inhibits Breast to Lung Metastasis

    EW-7197, a Novel ALK-5 Kinase Inhibitor, Potently Inhibits Breast to Lung Metastasis af Ji Yeon Son, So-Yeon Park, Sol‐Ji Kim, Seon Joo Lee, Sang-A Park, Min-Jin Kim, Seung Won Kim, Dae‐Kee Kim, Jeong‐Seok Nam, Yhun Yhong Sheen

    Udgivet 2014
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  9. 9
    Class I Histone Deacetylase-Selective Novel Synthetic Inhibitors Potently Inhibit Human Tumor Proliferation

    Class I Histone Deacetylase-Selective Novel Synthetic Inhibitors Potently Inhibit Human Tumor Proliferation af Jung‐Hyun Park, Yeonjoo Jung, Tai Young Kim, Sang Gyun Kim, Hyun-Soon Jong, Sang Eun Lee, Dae-Kee Kim, Jong‐Soo Lee, Noe Kyeong Kim, Tae‐You Kim, Yung‐Jue Bang

    Udgivet 2004
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  10. 10
    Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation

    Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation af Jeong-Hwan Yoon, Katsuko Sudo, Masahiko Kuroda, Mitsuyasu Kato, In‐Kyu Lee, Jin Soo Han, Susumu Nakae, Takeshi Imamura, Juryun Kim, Ji Hyeon Ju, Dae‐Kee Kim, Koichi Matsuzaki, Michael Weinstein, Isao Matsumoto, Takayuki Sumida, Mizuko Mamura

    Udgivet 2015
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  11. 11
    Vactosertib, TGF-β receptor I inhibitor, augments the sensitization of the anti-cancer activity of gemcitabine in pancreatic cancer

    Vactosertib, TGF-β receptor I inhibitor, augments the sensitization of the anti-cancer activity of gemcitabine in pancreatic cancer af Ji Eun Lee, Pureunchowon Lee, Young‐Chan Yoon, Beom Seok Han, Soyeon Ko, Min Seok Park, Yun Ji Lee, Sang Eun Kim, Yejin Cho, Joo Han Lim, Ji‐Kan Ryu, Soyeon Shim, Dae‐Kee Kim, Kyung Hee Jung, Soon‐Sun Hong

    Udgivet 2023
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  12. 12
    Activin receptor‐like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic <scp>T</scp> lymphocytes

    Activin receptor‐like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic <scp>T</scp> lymphocytes af Jeong‐Hwan Yoon, Su Myung Jung, Seok Hee Park, Mitsuyasu Kato, Tadashi Yamashita, In‐Kyu Lee, Katsuko Sudo, Susumu Nakae, Jin Soo Han, Ok‐Hee Kim, Byung‐Chul Oh, Takayuki Sumida, Masahiko Kuroda, Ji‐Hyeon Ju, Kyeong Cheon Jung, Seong Hoe Park, Dae‐Kee Kim, Mizuko Mamura

    Udgivet 2014
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  13. 13
    Activin receptor‐like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes

    Activin receptor‐like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes af Jeong‐Hwan Yoon, Su Myung Jung, Seok Hee Park, Mitsuyasu Kato, Tadashi Yamashita, In‐Kyu Lee, Katsuko Sudo, Susumu Nakae, Jin Soo Han, Ok‐Hee Kim, Byung‐Chul Oh, Takayuki Sumida, Masahiko Kuroda, Ji‐Hyeon Ju, Kyeong Cheon Jung, Seong Hoe Park, Dae‐Kee Kim, Mizuko Mamura

    Udgivet 2013
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