Search Results - D. Gulhan

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  1. 1
    The origins and genetic interactions of KRAS mutations are allele- and tissue-specific

    The origins and genetic interactions of KRAS mutations are allele- and tissue-specific by Joshua Cook, Giorgio Melloni, D. Gulhan, Peter J. Park, Kevin M. Haigis

    Published 2021
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  2. 2
    Accurate and sensitive mutational signature analysis with MuSiCal

    Accurate and sensitive mutational signature analysis with MuSiCal by Hu Jin, D. Gulhan, Benedikt Geiger, Daniel Ben-Isvy, David Geng, Viktor Ljungström, Peter J. Park

    Published 2024
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  3. 3
    Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns

    Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns by Emma V. Watson, Jake June-Koo Lee, D. Gulhan, Giorgio Melloni, Sergey V. Venev, Rayna Y. Magesh, Abdulrazak Frederick, Kunitoshi Chiba, Eric C. Wooten, Kamila Naxerova, Job Dekker, Peter J. Park, Stephen J. Elledge

    Published 2024
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  4. 4
    Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer

    Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer by Fernando Pérez‐Villatoro, Jaana Oikkonen, Julia Casado, Anastasiya Chernenko, D. Gulhan, Manuela Tumiati, Yilin Li, Kari Lavikka, Sakari Hietanen, Johanna Hynninen, Ulla‐Maija Haltia, Jaakko Tyrmi, Hannele Laivuori, Panagiotis A. Konstantinopoulos, Sampsa Hautaniemi, Liisa Kauppi, Anniina Färkkilä

    Published 2022
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  5. 5
    Linked-read analysis identifies mutations in single-cell DNA-sequencing data

    Linked-read analysis identifies mutations in single-cell DNA-sequencing data by Craig L. Bohrson, Alison R. Barton, Michael A. Lodato, Rachel E. Rodin, Lovelace J. Luquette, Vinay Viswanadham, D. Gulhan, Isidro Cortés‐Ciriano, Maxwell A. Sherman, Min‐Seok Kwon, Michael E. Coulter, Alon Galor, Christopher A. Walsh, Peter J. Park

    Published 2019
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  6. 6
    ERα-associated translocations underlie oncogene amplifications in breast cancer

    ERα-associated translocations underlie oncogene amplifications in breast cancer by Jake June-Koo Lee, Youngsook L. Jung, Taek-Chin Cheong, Jose Espejo Valle-Inclán, Chong Chu, D. Gulhan, Viktor Ljungström, Hu Jin, Vinay Viswanadham, Emma V. Watson, Isidro Cortés‐Ciriano, Stephen J. Elledge, Roberto Chiarle, David Pellman, Peter J. Park

    Published 2023
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  7. 7
    Mutational Signature 3 Detected from Clinical Panel Sequencing is Associated with Responses to Olaparib in Breast and Ovarian Cancers

    Mutational Signature 3 Detected from Clinical Panel Sequencing is Associated with Responses to Olaparib in Breast and Ovarian Cancers by Felipe Batalini, D. Gulhan, Victor Y. Mao, Antuan V. Tran, Madeline Polak, Niya Xiong, Nabihah Tayob, Nadine Tung, Eric P. Winer, Erica L. Mayer, Stian Knappskog, Per Eystein Lønning, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos, David B. Solit, Helen Won, Hans Petter Eikesdal, Peter J. Park, Gerburg M. Wulf

    Published 2022
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  8. 8
    Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements

    Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements by Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Yifan Zhao, Hu Jin, D. Gulhan, Javier Ganz, Sara Bizzotto, Samantha L. Kirkham, Tino Hochepied, Claude Libert, Alon Galor, Junho Kim, Michael A. Lodato, Juan I. Garaycoechea, Charles Gawad, Jay West, Christopher A. Walsh, Peter J. Park

    Published 2022
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  9. 9
    A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer

    A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer by Panagiotis A. Konstantinopoulos, Alexandre André Balieiro Anastácio da Costa, D. Gulhan, Elizabeth K. Lee, Su-Chun Cheng, Andrea E. Wahner Hendrickson, Bose Kochupurakkal, David L. Kolin, Elise C. Kohn, Joyce F. Liu, Elizabeth H. Stover, Jennifer Curtis, Nabihah Tayob, Madeline Polak, Dipanjan Chowdhury, Ursula A. Matulonis, Anniina Färkkilä, Alan D. D’Andrea, Geoffrey I. Shapiro

    Published 2021
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  10. 10
    Phase II Study of Avelumab in Patients With Mismatch Repair Deficient and Mismatch Repair Proficient Recurrent/Persistent Endometrial Cancer

    Phase II Study of Avelumab in Patients With Mismatch Repair Deficient and Mismatch Repair Proficient Recurrent/Persistent Endometrial Cancer by Panagiotis A. Konstantinopoulos, Weixiu Luo, Joyce F. Liu, D. Gulhan, Carolyn Krasner, Jeffrey J. Ishizuka, Allison Gockley, Mary K. Buss, Whitfield B. Growdon, H. Warren Crowe, Susana M. Campos, Neal I. Lindeman, Sarah J. Hill, Elizabeth H. Stover, Susan Schumer, Alexi A. Wright, Jennifer Curtis, Roxanne Quinn, Christin Whalen, Kathryn P. Gray, Richard T. Penson, Stephen A. Cannistra, Gini F. Fleming, Ursula A. Matulonis

    Published 2019
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  11. 11
    Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

    Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer by Anniina Färkkilä, D. Gulhan, Julia Casado, Connor A. Jacobson, Huy Nguyen, Bose Kochupurakkal, Zoltan Maliga, Clarence Yapp, Yu‐An Chen, Denis Schapiro, Yinghui Zhou, Julie R. Graham, Bruce J. Dezube, Pamela N. Münster, Sandro Santagata, Elizabeth Garcia, Scott J. Rodig, Ana Lako, Dipanjan Chowdhury, Geoffrey I. Shapiro, Ursula A. Matulonis, Peter J. Park, Sampsa Hautaniemi, Peter K. Sorger, Elizabeth M. Swisher, Alan D. D’Andrea, Panagiotis A. Konstantinopoulos

    Published 2020
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  12. 12
    The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing

    The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing by Rachel E. Rodin, Yanmei Dou, Minseok Kwon, Maxwell A. Sherman, Alissa M. D’Gama, Ryan N. Doan, Lariza M. Rento, Kelly M. Girskis, Craig L. Bohrson, Sonia N. Kim, Ajay Nadig, Lovelace J. Luquette, D. Gulhan, Christopher A. Walsh, Javier Ganz, Mollie B. Woodworth, Pengpeng Li, Rachel E. Rodin, Robert Hill, Sara Bizzotto, Zinan Zhou, Eunjung A. Lee, Alison R. Barton, Alissa M. D’Gama, Alon Galor, Craig L. Bohrson, Daniel H. Kwon, D. Gulhan, Elaine T. Lim, Isidro Cortes, Lovelace J. Luquette, Maxwell A. Sherman, Michael E. Coulter, Michael A. Lodato, Peter J. Park, Rebeca B. Monroy, Sonia N. Kim, Yanmei Dou, Andrew Chess, Attila Gulyás-Kovács, Chaggai Rosenbluh, Schahram Akbarian, Ben Langmead, Jeremy Thorpe, Jonathan Pevsner, Soonweng Cho, Andrew E. Jaffe, Apuã C.M. Paquola, Daniel R. Weinberger, Jennifer A. Erwin, Jooheon Shin, Richard E. Straub, Rujuta Narurkar, Alexej Abyzov, Taejeong Bae, Anjené Addington, David M. Panchision, Yanmei Dou, Geetha Senthil, Lora Bingaman, Tara Dutka, Thomas Lehner, Laura Saucedo-Cuevas, Tara Conniff, Kenneth Daily, Mette A. Peters, Fred H. Gage, Meiyan Wang, Patrick Reed, Sara B. Linker, Alex E. Urban, Bo Zhou, Xiaowei Zhu, Aitor Serres, David Juan, Inna Povolotskaya, Irene Lobón, Manuel Solís-Moruno, Raquel García-Pérez, Tomàs Marquès‐Bonet, Gary W. Mathern, Jing Gu, Joseph G. Gleeson, Laurel Ball, Renee D. George, Tiziano Pramparo, Diane A. Flasch, Trenton J. Frisbie, Jeffrey M. Kidd, John B. Moldovan, John V. Moran, Kenneth Y. Kwan, Ryan E. Mills, Sarah B. Emery, Weichen Zhou, Yifan Wang, Aakrosh Ratan, Michael J. McConnell, Flora M. Vaccarino, Gianfilippo Coppola

    Published 2021
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  13. 13
    Somatic mosaicism reveals clonal distributions of neocortical development

    Somatic mosaicism reveals clonal distributions of neocortical development by Martin W. Breuss, Xiaoxu Yang, Johannes C. M. Schlachetzki, Danny Antaki, Addison J. Lana, Xin Xu, Changuk Chung, Guoliang Chai, Valentina Stanley, Qiong Song, Traci Fang Newmeyer, An T. Nguyen, S O'Brien, Marten A. Hoeksema, Beibei Cao, Alexi Nott, Jennifer McEvoy‐Venneri, Martina P. Pasillas, Scott T. Barton, Brett Copeland, Shareef Nahas, Lucitia Van Der Kraan, Yan Ding, Joseph G. Gleeson, Martin W. Breuss, Xiaoxu Yang, Danny Antaki, Changuk Chung, Dan Averbuj, Eric Courchesne, Laurel Ball, Subhojit Roy, Daniel R. Weinberger, Andrew E. Jaffe, Apuã C.M. Paquola, Jennifer A. Erwin, Jooheon Shin, Michael J. McConnell, Richard E. Straub, Rujuta Narurkar, Gary W. Mathern, Christopher A. Walsh, Alice Lee, August Yue Huang, Alissa M. D’Gama, Caroline Dias, Eduardo A. Maury, Javier Ganz, Michael A. Lodato, Michael B. Miller, Pengpeng Li, Rachel E. Rodin, Rebeca Borges-Monroy, Robert Hill, Sara Bizzotto, Sattar Khoshkhoo, Sonia Kim, Zinan Zhou, Peter J. Park, Alison R. Barton, Alon Galor, Chong Chu, Craig L. Bohrson, D. Gulhan, Elaine T. Lim, Eun‐Cheon Lim, Giorgio Melloni, Isidro Cortes, Jake Lee, Joe Luquette, Lixing Yang, Maxwell A. Sherman, Michael E. Coulter, Min‐Seok Kwon, Semin Lee, Soo In Lee, Vinary Viswanadham, Yanmei Dou, Andrew Chess, Attila Jones, Chaggai Rosenbluh, Schahram Akbarian, Ben Langmead, Jeremy Thorpe, Sean Cho, Alexej Abyzov, Taejeong Bae, Yeongjun Jang, Yifan Wang, Cindy Molitor, Mette A. Peters, Fred H. Gage, Meiyan Wang, Patrick Reed, Sara B. Linker, Alexander E. Urban, Bo Zhou, Reenal Pattni, Xiaowei Zhu, Aitor Serres Amero

    Published 2022
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  14. 14
    Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability

    Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability by Taejeong Bae, Liana Fasching, Yifan Wang, Joo Heon Shin, Milovan Šuvakov, Yeongjun Jang, Scott Norton, Caroline Dias, Jessica Mariani, Alexandre Jourdon, Feinan Wu, Arijit Panda, Reenal Pattni, Yasmine Chahine, Rebecca C. Yeh, Rosalinda C. Roberts, Anita Hüttner, Joel E. Kleinman, Thomas M. Hyde, Richard E. Straub, Christopher A. Walsh, Alexander E. Urban, James F. Leckman, Daniel R. Weinberger, Flora M. Vaccarino, Alexej Abyzov, Christopher A. Walsh, Peter J. Park, Nenad Šestan, Daniel R. Weinberger, John V. Moran, Fred H. Gage, Flora M. Vaccarino, Joseph G. Gleeson, Gary W. Mathern, Eric Courchesne, Subhojit Roy, Andrew Chess, Schahram Akbarian, Sara Bizzotto, Michael E. Coulter, Caroline Dias, Alissa M. D’Gama, Javier Ganz, Robert Hill, August Yue Huang, Sattar Khoshkhoo, Sonia Kim, Alice Lee, Michael A. Lodato, Eduardo A. Maury, Michael Miller, Rebeca Borges-Monroy, Rachel E. Rodin, Zinan Zhou, Craig L. Bohrson, Chong Chu, Isidro Cortés‐Ciriano, Yanmei Dou, Alon Galor, D. Gulhan, Min‐Seok Kwon, Joe Luquette, Maxwell A. Sherman, Vinay Viswanadham, Attila Jones, Chaggai Rosenbluh, Sean Cho, Ben Langmead, Jeremy Thorpe, Jennifer A. Erwin, Andrew E. Jaffe, Michael J. McConnell, Rujuta Narurkar, Apuã C.M. Paquola, Jooheon Shin, Richard E. Straub, Alexej Abyzov, Taejeong Bae, Yeongjun Jang, Yifan Wang, Cindy Molitor, Mette A. Peters, Sara B. Linker, Patrick Reed, Meiyan Wang, Alexander E. Urban, Bo Zhou, Xiaowei Zhu, Reenal Pattni, Aitor Serres Amero, David Juan, Irene Lobón, Tomàs Marquès‐Bonet, Manuel Solis Moruno, Raquel García Pérez, Inna Povolotskaya, Eduardo Soriano, Danny Antaki, Dan Averbuj

    Published 2022
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  15. 15
    Control-independent mosaic single nucleotide variant detection with DeepMosaic

    Control-independent mosaic single nucleotide variant detection with DeepMosaic by Xiaoxu Yang, Xin Xu, Martin W. Breuss, Danny Antaki, Laurel Ball, Changuk Chung, Jiawei Shen, Chen Li, Renee D. George, Yifan Wang, Taejeong Bae, Yuhe Cheng, Alexej Abyzov, Liping Wei, Ludmil B. Alexandrov, Jonathan Sebat, Dan Averbuj, Subhojit Roy, Eric Courchesne, August Yue Huang, Alissa M. D’Gama, Caroline Dias, Christopher A. Walsh, Javier Ganz, Michael A. Lodato, Michael Miller, Pengpeng Li, Rachel E. Rodin, Robert Hill, Sara Bizzotto, Sattar Khoshkhoo, Zinan Zhou, Alice Lee, Alison R. Barton, Alon Galor, Chong Chu, Craig L. Bohrson, D. Gulhan, Eduardo A. Maury, Elaine T. Lim, Eun‐Cheon Lim, Giorgio Melloni, Isidro Cortes, Jake Lee, Joe Luquette, Lixing Yang, Maxwell A. Sherman, Michael E. Coulter, Min‐Seok Kwon, Peter J. Park, Rebeca Borges-Monroy, Semin Lee, Sonia Kim, Soo In Lee, Vinary Viswanadham, Yanmei Dou, Andrew Chess, Attila Jones, Chaggai Rosenbluh, Schahram Akbarian, Ben Langmead, Jeremy Thorpe, Sean Cho, Andrew E. Jaffe, Apuã C.M. Paquola, Daniel M. Weinberger, Jennifer A. Erwin, Jooheon Shin, Michael V. McConnell, Richard E. Straub, Rujuta Narurkar, Yeongjun Jang, Cindy Molitor, Mette A. Peters, Fred H. Gage, Meiyan Wang, Patrick Reed, Sara B. Linker, Alexander E. Urban, Bo Zhou, Xiaowei Zhu, Aitor Serres Amero, David Juan, Inna Povolotskaya, Irene Lobón, Manuel Solis Moruno, Raquel García-Pérez, Tomàs Marquès‐Bonet, Eduardo Soriano, Gary W. Mathern, Diane A. Flasch, Trenton J. Frisbie, Huira C. Kopera, Jeffrey M. Kidd, John B. Moldovan, John V. Moran, Kenneth Y. Kwan, Ryan E. Mills, Sarah B. Emery, Weichen Zhou

    Published 2023
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