Search Results - Curtis Younkin

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  1. 1
    Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

    Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease by Minerva M. Carrasquillo, Fanggeng Zou, V. Shane Pankratz, Samantha L. Wilcox, Li Ma, Louise P. Walker, Samuel Younkin, Curtis Younkin, Linda H. Younkin, Gina Bisceglio, Nilüfer Ertekin‐Taner, Julia E. Crook, Dennis W. Dickson, Ronald C. Petersen, Neill R. Graff‐Radford, Steven G. Younkin

    Published 2009
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  2. 2
    Late-onset Alzheimer disease risk variants mark brain regulatory loci

    Late-onset Alzheimer disease risk variants mark brain regulatory loci by Mariet Allen, Michaela Kachadoorian, Minerva M. Carrasquillo, Aditya V. Karhade, Lester S. Manly, Jeremy D. Burgess, Chen Wang, Daniel Serie, Xue Wang, Joanna Siuda, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia E. Crook, Christopher Medway, Thuy Nguyen, Li Ma, Kimberly G. Malphrus, Sarah Lincoln, Ronald C. Petersen, Neill R. Graff‐Radford, Yan W. Asmann, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner

    Published 2015
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  3. 3
    Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci

    Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci by Mariet Allen, Jeremy D. Burgess, Travis Ballard, Daniel Serie, Xue Wang, Curtis Younkin, Zhifu Sun, Naomi Kouri, Saurabh Baheti, Chen Wang, Minerva M. Carrasquillo, Thuy Nguyen, Sarah Lincoln, Kimberly G. Malphrus, Melissa E. Murray, Todd E. Golde, Nathan D. Price, Steven G. Younkin, Gerard D. Schellenberg, Yan W. Asmann, Tamás Ördög, Julia E. Crook, Dennis W. Dickson, Nilüfer Ertekin‐Taner

    Published 2016
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  4. 4
    Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy

    Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy by Mariet Allen, Xue Wang, Daniel Serie, Samantha L. Strickland, Jeremy D. Burgess, Shunsuke Koga, Curtis Younkin, Thuy Nguyen, Kimberly G. Malphrus, Sarah Lincoln, Melissa Alamprese, Kuixi Zhu, Rui Chang, Minerva M. Carrasquillo, Naomi Kouri, Melissa E. Murray, Joseph S. Reddy, Cory C. Funk, Nathan D. Price, Todd E. Golde, Steven G. Younkin, Yan W. Asmann, Julia E. Crook, Dennis W. Dickson, Nilüfer Ertekin‐Taner

    Published 2018
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  5. 5
    TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease

    TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease by Paramita Chakrabarty, Andrew Li, Thomas B. Ladd, Michael R. Strickland, Emily J. Koller, Jeremy D. Burgess, Cory C. Funk, Pedro E. Cruz, Mariet Allen, Mariya Yaroshenko, Xue Wang, Curtis Younkin, Joseph S. Reddy, Benjamin Lohrer, Leonie S. Mehrke, Brenda D. Moore, Xuefei Liu, Carolina Ceballos‐Diaz, Awilda M. Rosario, Christopher Medway, Christopher Janus, Hongdong Li, Dennis W. Dickson, Benoit I. Giasson, Nathan D. Price, Steven G. Younkin, Nilüfer Ertekin‐Taner, Todd E. Golde

    Published 2018
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  6. 6
    Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

    Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci by Philip L. De Jager, Gyan Srivastava, Katie Lunnon, Jeremy D. Burgess, Leonard C. Schalkwyk, Lei Yu, Matthew L. Eaton, Brendan T Keenan, Jason Ernst, Cristin McCabe, Anna Tang, Towfique Raj, Joseph M. Replogle, Wendy Brodeur, Stacey Gabriel, High Seng Chai, Curtis Younkin, Steven G. Younkin, Fanggeng Zou, Moshe Szyf, Charles B. Epstein, Julie A. Schneider, B Bernstein, Alex Meissner, Nilüfer Ertekin‐Taner, Lori B. Chibnik, Manolis Kellis, Jonathan Mill, David A. Bennett

    Published 2014
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  7. 7
    A candidate regulatory variant at the <i>TREM</i> gene cluster associates with decreased Alzheimer's disease risk and increased <i>TREML1</i> and <i>TREM2</i> brain gene expression

    A candidate regulatory variant at the <i>TREM</i> gene cluster associates with decreased Alzheimer's disease risk and increased <i>TREML1</i> and <i>TREM2</i> brain gene expression by Minerva M. Carrasquillo, Mariet Allen, Jeremy D. Burgess, Xue Wang, Samantha L. Strickland, Shivani Aryal, Joanna Siuda, Michaela Kachadoorian, Christopher Medway, Curtis Younkin, Asha Nair, Chen Wang, Pritha Chanana, Daniel Serie, Thuy Nguyen, Sarah Lincoln, Kimberly G. Malphrus, Kevin Morgan, Todd E. Golde, Nathan D. Price, Charles C. White, Philip L. De Jager, David A. Bennett, Yan W. Asmann, Julia E. Crook, Ronald Petersen, Caroline Graff, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner

    Published 2016
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  8. 8
    ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans

    ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans by Olivia J. Conway, Minerva M. Carrasquillo, Xue Wang, Jenny M. Bredenberg, Joseph S. Reddy, Samantha L. Strickland, Curtis Younkin, Jeremy D. Burgess, Mariet Allen, Sarah Lincoln, Thuy Nguyen, Kimberly G. Malphrus, Alexandra I. Soto, Ronald L. Walton, Bradley F. Boeve, Ronald C. Petersen, John A. Lucas, Tanis J. Ferman, William P. Cheshire, Jay A. van Gerpen, Ryan J. Uitti, Zbigniew K. Wszołek, Owen A. Ross, Dennis W. Dickson, Neill R. Graff‐Radford, Nilüfer Ertekin‐Taner

    Published 2018
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  9. 9
    Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

    Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants by Fanggeng Zou, High Seng Chai, Curtis Younkin, Mariet Allen, Julia E. Crook, V. Shane Pankratz, Minerva M. Carrasquillo, Christopher Rowley, Asha Nair, Sumit Middha, Sooraj Maharjan, Thuy Nguyen, Li Ma, Kimberly G. Malphrus, Ryan Palusak, Sarah Lincoln, Gina Bisceglio, Constantin Georgescu, Naomi Kouri, Christopher P. Kolbert, Jin Jen, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak‐Vance, Lindsay A. Farrer, Gerard D. Schellenberg, Ronald C. Petersen, Neill R. Graff‐Radford, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner

    Published 2012
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  10. 10
    Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

    Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels by Mariet Allen, Michaela Kachadoorian, Zachary Quicksall, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia E. Crook, V. Shane Pankratz, Minerva M. Carrasquillo, Siddharth Krishnan, Thuy Nguyen, Li Ma, Kimberly G. Malphrus, Sarah Lincoln, Gina Bisceglio, Christopher P. Kolbert, Jin Jen, Shubhabrata Mukherjee, John Kauwe, Paul K. Crane, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak‐Vance, Lindsay A. Farrer, Gerard D. Schellenberg, Joseph E. Parisi, Ronald Petersen, Neill R. Graff‐Radford, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner

    Published 2014
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  11. 11
    Novel late-onset Alzheimer disease loci variants associate with brain gene expression

    Novel late-onset Alzheimer disease loci variants associate with brain gene expression by Mariet Allen, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia E. Crook, V. Shane Pankratz, Minerva M. Carrasquillo, Christopher Rowley, Asha Nair, Sumit Middha, Sooraj Maharjan, Thuy Nguyen, Li Ma, Kimberly G. Malphrus, Ryan Palusak, Sarah Lincoln, Gina Bisceglio, Constantin Georgescu, Debra A. Schultz, Fariborz Rakhshan, Christopher P. Kolbert, Jin Jen, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak‐Vance, Lindsay A. Farrer, Gerard D. Schellenberg, Ronald C. Petersen, Neill R. Graff‐Radford, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner

    Published 2012
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  12. 12
    Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases

    Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases by Mariet Allen, Minerva M. Carrasquillo, Cory C. Funk, Ben Heavner, Fanggeng Zou, Curtis Younkin, Jeremy D. Burgess, High-Seng Chai, Julia E. Crook, James A. Eddy, Hong‐Dong Li, Ben Logsdon, Mette A. Peters, Kristen K. Dang, Xue Wang, Daniel Serie, Chen Wang, Thuy Nguyen, Sarah Lincoln, Kimberly G. Malphrus, Gina Bisceglio, Li Ma, Todd E. Golde, Lara M. Mangravite, Yan W. Asmann, Nathan D. Price, Ronald Petersen, Neill R. Graff‐Radford, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner

    Published 2016
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  13. 13
    Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications

    Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications by Mariet Allen, Fanggeng Zou, High Seng Chai, Curtis Younkin, Richard J. Miles, Asha Nair, Julia E. Crook, V. Shane Pankratz, Minerva M. Carrasquillo, Christopher Rowley, Thuy Nguyen, Li Ma, Kimberly G. Malphrus, Gina Bisceglio, Alexandra I. Ortolaza, Ryan Palusak, Sumit Middha, Sooraj Maharjan, Constantin Georgescu, Debra A. Schultz, Fariborz Rakhshan, Christopher P. Kolbert, Jin Jen, Sigrid Botne Sando, Jan Aasly, Maria Barcikowska, Ryan J. Uitti, Zbigniew K. Wszołek, Owen A. Ross, Ronald Petersen, Neill R. Graff‐Radford, Dennis W. Dickson, Steven G. Younkin, Nilüfer Ertekin‐Taner

    Published 2012
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  14. 14
    Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

    Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases by Mariet Allen, Xue Wang, Jeremy D. Burgess, Jens O. Watzlawik, Daniel Serie, Curtis Younkin, Thuy Nguyen, Kimberly G. Malphrus, Sarah Lincoln, Minerva M. Carrasquillo, Charlotte C.G. Ho, Paramita Chakrabarty, Samantha L. Strickland, Melissa E. Murray, Vivek Swarup, Daniel H. Geschwind, Nicholas T. Seyfried, Eric B. Dammer, James J. Lah, Allan I. Levey, Todd E. Golde, Cory C. Funk, Hongdong Li, Nathan D. Price, Ronald C. Petersen, Neill R. Graff‐Radford, Steven G. Younkin, Dennis W. Dickson, Julia Crook, Yan W. Asmann, Nilüfer Ertekin‐Taner

    Published 2017
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  15. 15
    Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, Aß, and Alzheimer's Disease

    Concordant Association of Insulin Degrading Enzyme Gene (IDE) Variants with IDE mRNA, Aß, and Alzheimer's Disease by Minerva M. Carrasquillo, Olivia Belbin, Fanggeng Zou, Mariet Allen, Nilüfer Ertekin‐Taner, Morad Ansari, Samantha L. Wilcox, Mariah R. Kashino, Li Ma, Linda H. Younkin, Samuel Younkin, Curtis Younkin, Toros Dincman, Melissa E. Howard, Chanley C. Howell, Chloë M. Stanton, Christopher M. Watson, Michael Crump, Véronique Vitart, Caroline Hayward, Nicholas D. Hastie, Igor Rudan, Harry Campbell, Ozren Polašek, Kristelle Brown, Peter Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Patrick G. Kehoe, David Mann, A. David Smith, Helen Beaumont, Donald Warden, Clive Holmes, Reinhard Heun, Heike Kölsch, Noor Kalsheker, V. Shane Pankratz, Dennis W. Dickson, Neill R. Graff‐Radford, Ronald Petersen, Alan F. Wright, Steven G. Younkin, Kevin Morgan

    Published 2010
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  16. 16
    Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

    Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy by Naomi Kouri, Owen A. Ross, Beth A. Dombroski, Curtis Younkin, Daniel Serie, Alexandra I. Soto‐Ortolaza, Matthew Baker, Ni Cole A. Finch, Hyejin Yoon, Jungsu Kim, Shinsuke Fujioka, Catriona McLean, Bernardino Ghetti, Salvatore Spina, Laura B. Cantwell, Martin R. Farlow, Jordan Grafman, Edward D. Huey, Mi Ryung Han, Sherry Beecher, Evan Geller, Hans A. Kretzschmar, Sigrun Roeber, Marla Gearing, Jorge L. Juncos, Jean Paul Vonsattel, Vivianna M. Van Deerlin, Murray Grossman, Howard I. Hurtig, Owen A. Ross, Steven E. Arnold, John Q. Trojanowski, Virginia M. Lee, Gregor K. Wenning, Charles L. White, Günter U. Höglinger, Ulrich Müller, Bernie Devlin, Lawrence I. Golbe, Julia E. Crook, Joseph E. Parisi, Bradley F. Boeve, Keith A. Josephs, Zbigniew K. Wszołek, Ryan J. Uitti, Neill R. Graff‐Radford, Irene Litvan, Steven G. Younkin, Li-San Wang, Nilüfer Ertekin‐Taner, Rosa Rademakers, Hakon Hakonarsen, Daniela Berg, Dennis W. Dickson

    Published 2015
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