Canlyniadau Chwilio - Cucchi, Danilo

LACTB-mediated tumour suppression by increased mitochondrial lipid metabolism gan Cucchi, Danilo, Mauro, Claudio

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The emerging relationship between metabolism and DNA repair gan Cucchi, Danilo, Gibson, Amy, Martin, Sarah a

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Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma gan Cucchi, Danilo, Occhione, Maria Anna, Gulino, Alberto, De Smaele, Enrico

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Fatty acids - from energy substrates to key regulators of cell survival, proliferation and effector function gan Cucchi, Danilo, Camacho-Muñoz, Dolores, Certo, Michelangelo, Pucino, Valentina, Nicolaou, Anna, Mauro, Claudio

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Endothelial cell and T‐cell crosstalk: Targeting metabolism as a therapeutic approach in chronic inflammation gan Certo, Michelangelo, Elkafrawy, Hagar, Pucino, Valentina, Cucchi, Danilo, Cheung, Kenneth C.P., Mauro, Claudio

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The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability gan Heride, Claire, Rigden, Daniel J., Bertsoulaki, Erithelgi, Cucchi, Danilo, De Smaele, Enrico, Clague, Michael J., Urbé, Sylvie

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BCAT1 controls metabolic reprogramming in activated human macrophages and is associated with inflammatory diseases gan Papathanassiu, Adonia E., Ko, Jeong-Hun, Imprialou, Martha, Bagnati, Marta, Srivastava, Prashant K., Vu, Hong A., Cucchi, Danilo, McAdoo, Stephen P., Ananieva, Elitsa A., Mauro, Claudio, Behmoaras, Jacques

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In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors gan Benvenuto, Monica, Masuelli, Laura, De Smaele, Enrico, Fantini, Massimo, Mattera, Rosanna, Cucchi, Danilo, Bonanno, Elena, Di Stefano, Enrica, Frajese, Giovanni Vanni, Orlandi, Augusto, Screpanti, Isabella, Gulino, Alberto, Modesti, Andrea, Bei, Roberto

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The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint gan Di Magno, Laura, Basile, Alessio, Coni, Sonia, Manni, Simona, Sdruscia, Giulia, D'Amico, Davide, Antonucci, Laura, Infante, Paola, De Smaele, Enrico, Cucchi, Danilo, Ferretti, Elisabetta, Di Marcotullio, Lucia, Screpanti, Isabella, Canettieri, Gianluca

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MLH1 deficiency leads to deregulated mitochondrial metabolism gan Rashid, Sukaina, Freitas, Marta O., Cucchi, Danilo, Bridge, Gemma, Yao, Zhi, Gay, Laura, Williams, Marc, Wang, Jun, Suraweera, Nirosha, Silver, Andrew, McDonald, Stuart A. C., Chelala, Claude, Szabadkai, Gyorgy, Martin, Sarah A.

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Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma gan De Smaele, Enrico, Di Marcotullio, Lucia, Moretti, Marta, Pelloni, Marianna, Occhione, Maria Anna, Infante, Paola, Cucchi, Danilo, Greco, Azzura, Pietrosanti, Laura, Todorovic, Jelena, Coni, Sonia, Canettieri, Gianluca, Ferretti, Elisabetta, Bei, Roberto, Maroder, Marella, Screpanti, Isabella, Gulino, Alberto

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Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4(+) T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals gan Mauro, Claudio, Smith, Joanne, Cucchi, Danilo, Coe, David, Fu, Hongmei, Bonacina, Fabrizia, Baragetti, Andrea, Cermenati, Gaia, Caruso, Donatella, Mitro, Nico, Catapano, Alberico L., Ammirati, Enrico, Longhi, Maria P., Okkenhaug, Klaus, Norata, Giuseppe D., Marelli-Berg, Federica M.

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Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4(+) T Cell Metabolic Rewiring gan Pucino, Valentina, Certo, Michelangelo, Bulusu, Vinay, Cucchi, Danilo, Goldmann, Katriona, Pontarini, Elena, Haas, Robert, Smith, Joanne, Headland, Sarah E., Blighe, Kevin, Ruscica, Massimiliano, Humby, Frances, Lewis, Myles J., Kamphorst, Jurre J., Bombardieri, Michele, Pitzalis, Costantino, Mauro, Claudio

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β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells gan Miele, Evelina, Po, Agnese, Begalli, Federica, Antonucci, Laura, Mastronuzzi, Angela, Marras, Carlo Efisio, Carai, Andrea, Cucchi, Danilo, Abballe, Luana, Besharat, Zein Mersini, Catanzaro, Giuseppina, Infante, Paola, Di Marcotullio, Lucia, Canettieri, Gianluca, De Smaele, Enrico, Screpanti, Isabella, Locatelli, Franco, Ferretti, Elisabetta

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Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors gan Infante, Paola, Mori, Mattia, Alfonsi, Romina, Ghirga, Francesca, Aiello, Federica, Toscano, Sara, Ingallina, Cinzia, Siler, Mariangela, Cucchi, Danilo, Po, Agnese, Miele, Evelina, D'Amico, Davide, Canettieri, Gianluca, De Smaele, Enrico, Ferretti, Elisabetta, Screpanti, Isabella, Uccello Barretta, Gloria, Botta, Maurizio, Botta, Bruno, Gulino, Alberto, Di Marcotullio, Lucia

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KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 gan Spiombi, Eleonora, Angrisani, Annapaola, Fonte, Simone, De Feudis, Giuseppina, Fabretti, Francesca, Cucchi, Danilo, Izzo, Mariapaola, Infante, Paola, Miele, Evelina, Po, Agnese, Di Magno, Laura, Magliozzi, Roberto, Guardavaccaro, Daniele, Maroder, Marella, Canettieri, Gianluca, Giannini, Giuseppe, Ferretti, Elisabetta, Gulino, Alberto, Di Marcotullio, Lucia, Moretti, Marta, De Smaele, Enrico

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