Canlyniadau Chwilio - Critchlow, Susan E

CD147 subunit of lactate/H(+) symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors gan Le Floch, Renaud, Chiche, Johanna, Marchiq, Ibtissam, Naiken, Tanesha, Ilc, Karine, Murray, Clare M., Critchlow, Susan E., Roux, Danièle, Simon, Marie-Pierre, Pouysségur, Jacques

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Inhibition of Monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport gan Bola, Becky M., Chadwick, Amy L., Michopoulos, Filippos, Blount, Kathryn G., Telfer, Brian A., Williams, Kaye J., Smith, Paul D, Critchlow, Susan E., Stratford, Ian J.

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Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters gan Mehibel, Manal, Ortiz-Martinez, Fernando, Voelxen, Nadine, Boyers, Amy, Chadwick, Amy, Telfer, Brian A., Mueller-Klieser, Wolfgang, West, Catharine M., Critchlow, Susan E., Williams, Kaye J., Stratford, Ian J.

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3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers gan Jones, Dylan T., Valli, Alessandro, Haider, Syed, Zhang, Qifeng, Smethurst, Elizabeth A., Schug, Zachary T., Peck, Barrie, Aboagye, Eric O., Critchlow, Susan E., Schulze, Almut, Gottlieb, Eyal, Wakelam, Michael J.O., Harris, Adrian L.

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Activity of the Monocarboxylate Transporter 1 inhibitor AZD3965 in Small Cell Lung Cancer gan Polański, Radosław, Hodgkinson, Cassandra L., Fusi, Alberto, Nonaka, Daisuke, Priest, Lynsey, Kelly, Paul, Trapani, Francesca, Bishop, Paul W., White, Anne, Critchlow, Susan E., Smith, Paul D., Blackhall, Fiona, Dive, Caroline, Morrow, Christopher J.

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Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt’s lymphoma anti-tumor activity gan Curtis, Nicola J., Mooney, Lorraine, Hopcroft, Lorna, Michopoulos, Filippos, Whalley, Nichola, Zhong, Haihong, Murray, Clare, Logie, Armelle, Revill, Mitchell, Byth, Kate F., Benjamin, Amanda D., Firth, Mike A., Green, Stephen, Smith, Paul D., Critchlow, Susan E.

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Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma gan Noble, Richard A., Bell, Natalie, Blair, Helen, Sikka, Arti, Thomas, Huw, Phillips, Nicole, Nakjang, Sirintra, Miwa, Satomi, Crossland, Rachel, Rand, Vikki, Televantou, Despina, Long, Anna, Keun, Hector C., Bacon, Chris M., Bomken, Simon, Critchlow, Susan E., Wedge, Stephen R.

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MCT1 modulates cancer cell pyruvate export and growth of tumors that co-express MCT1 and MCT4 gan Hong, Candice Sun, Graham, Nicholas A., Gu, Wen, Camacho, Carolina Espindola, Mah, Vei, Maresh, Erin L., Alavi, Mohammed, Bagryanova, Lora, Krotee, Pascal A. L., Gardner, Brian K., Behbahan, Iman Saramipoor, Horvath, Steve, Chia, David, Mellinghoff, Ingo K., Hurvitz, Sara A., Dubinett, Steven M., Critchlow, Susan E., Kurdistani, Siavash K., Goodglick, Lee, Braas, Daniel, Graeber, Thomas G., Christofk, Heather R.

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Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments gan Peck, Barrie, Schug, Zachary T., Zhang, Qifeng, Dankworth, Beatrice, Jones, Dylan T., Smethurst, Elizabeth, Patel, Rachana, Mason, Susan, Jiang, Ming, Saunders, Rebecca, Howell, Michael, Mitter, Richard, Spencer-Dene, Bradley, Stamp, Gordon, McGarry, Lynn, James, Daniel, Shanks, Emma, Aboagye, Eric O., Critchlow, Susan E., Leung, Hing Y., Harris, Adrian L., Wakelam, Michael J. O., Gottlieb, Eyal, Schulze, Almut

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AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo gan Loddick, Sarah A, Ross, Sarah J, Thomason, Andrew G, Robinson, David M, Walker, Graeme E, Dunkley, Tom PJ, Brave, Sandra R, Broadbent, Nicola, Stratton, Natalie C, Trueman, Dawn, Mouchet, Elizabeth, Shaheen, Fadhel S, Jacobs, Vivien N, Cumberbatch, Marie, Wilson, Joanne, Jones, Rhys D O, Bradbury, Robert H, Rabow, Alfred, Gaughan, Luke, Womack, Chris, Barry, Simon T, Robson, Craig N, Critchlow, Susan E, Wedge, Stephen R, Brooks, Nigel A

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Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress gan Schug, Zachary T., Peck, Barrie, Jones, Dylan T., Zhang, Qifeng, Grosskurth, Shaun, Alam, Israt S., Goodwin, Louise M., Smethurst, Elizabeth, Mason, Susan, Blyth, Karen, McGarry, Lynn, James, Daniel, Shanks, Emma, Kalna, Gabriela, Saunders, Rebecca E., Jiang, Ming, Howell, Michael, Lassailly, Francois, Thin, May Zaw, Spencer-Dene, Bradley, Stamp, Gordon, van den Broek, Niels J.F., Mackay, Gillian, Bulusu, Vinay, Kamphorst, Jurre J., Tardito, Saverio, Strachan, David, Harris, Adrian L., Aboagye, Eric O., Critchlow, Susan E., Wakelam, Michael J.O., Schulze, Almut, Gottlieb, Eyal

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