Search Results - Craig Lockhart

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  1. 1
    Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy

    Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy by Nilay Thakkar, A. Craig Lockhart, Wooin Lee

    Published 2015
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  2. 2
    Immune checkpoints and immunotherapy for colorectal cancer

    Immune checkpoints and immunotherapy for colorectal cancer by Preet Paul Singh, Piyush Kumar Sharma, Gayathri Krishnan, A. Craig Lockhart

    Published 2015
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  3. 3
    Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids

    Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids by Nagaraj S. Nagathihalli, Yugandhar Beesetty, Wooin Lee, M. Kay Washington, Xi Chen, A. Craig Lockhart, Nipun B. Merchant

    Published 2014
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  4. 4
    Mammaglobin-A cDNA vaccination of breast cancer patients induces antigen-specific cytotoxic CD4+ICOShi T cells

    Mammaglobin-A cDNA vaccination of breast cancer patients induces antigen-specific cytotoxic CD4+ICOShi T cells by Venkataswarup Tiriveedhi, Timothy P. Fleming, Peter S. Goedegebuure, Michael Naughton, X. Cynthia, Craig Lockhart, Feng Gao, William E. Gillanders, T. Mohanakumar

    Published 2012
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  5. 5
    Vascular Endothelial Growth Factor-Trap Overcomes Defects in Dendritic Cell Differentiation but Does Not Improve Antigen-Specific Immune Responses

    Vascular Endothelial Growth Factor-Trap Overcomes Defects in Dendritic Cell Differentiation but Does Not Improve Antigen-Specific Immune Responses by Ingo Fricke, Noweeda Mirza, Jakob Dupont, Craig Lockhart, Autumn L. Jackson, Ji‐Hyun Lee, Jeffrey A. Sosman, Dmitry I. Gabrilovich

    Published 2007
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  6. 6
    Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma

    Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma by Daoxiang Zhang, Lin Li, Hongmei Jiang, Brett L. Knolhoff, A. Craig Lockhart, Andrea Wang‐Gillam, David G. DeNardo, Marianna B. Ruzinova, Kian‐Huat Lim

    Published 2016
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  7. 7
    Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies

    Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies by Zhou, Xiaofei, Nemunaitis, John, Pant, Shubham, Bauer, Todd M., Patel, Manish, Sarantopoulos, John, Craig Lockhart, A., Goodman, Daniel, Huebner, Dirk, Mould, Diane R., Venkatakrishnan, Karthik

    Published 2017
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  8. 8
    Clinical T2N0 Esophageal Cancer: Identifying Pretreatment Characteristics Associated With Pathologic Upstaging and the Potential Role for Induction Therapy

    Clinical T2N0 Esophageal Cancer: Identifying Pretreatment Characteristics Associated With Pathologic Upstaging and the Potential Role for Induction Therapy by Pamela Samson, Varun Puri, Clifford G. Robinson, Craig Lockhart, Danielle Carpenter, Stephen Broderick, Daniel Kreisel, Alexander S. Krupnick, G. Alexander Patterson, Bryan F. Meyers, Traves D. Crabtree

    Published 2016
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  9. 9
    Neoadjuvant Chemotherapy versus Chemoradiation Prior to Esophagectomy: Impact on Rate of Complete Pathologic Response and Survival in Esophageal Cancer Patients

    Neoadjuvant Chemotherapy versus Chemoradiation Prior to Esophagectomy: Impact on Rate of Complete Pathologic Response and Survival in Esophageal Cancer Patients by Pamela Samson, Clifford G. Robinson, Jeffrey D. Bradley, A. Craig Lockhart, Varun Puri, Stephen Broderick, Daniel Kreisel, Alexander S. Krupnick, G. Alexander Patterson, Bryan Meyers, Traves D. Crabtree

    Published 2016
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  10. 10
    Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies

    Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies by Zhou, Xiaofei, Pant, Shubham, Nemunaitis, John, Craig Lockhart, A., Falchook, Gerald, Bauer, Todd M., Patel, Manish, Sarantopoulos, John, Bargfrede, Michael, Muehler, Andreas, Rangachari, Lakshmi, Zhang, Bin, Venkatakrishnan, Karthik

    Published 2017
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  11. 11
    Overexpression of OATP1B3 Confers Apoptotic Resistance in Colon Cancer

    Overexpression of OATP1B3 Confers Apoptotic Resistance in Colon Cancer by Wooin Lee, Abbes Belkhiri, A. Craig Lockhart, Nipun B. Merchant, Hartmut Glaeser, Elizabeth I. Harris, M. Kay Washington, Elizabeth M. Brunt, Alex Zaika, Richard B. Kim, Wael El‐Rifai

    Published 2008
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  12. 12
    A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer

    A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer by X. Cynthia, César Sánchez, Feng Gao, Robert J. Crowder, Michael Naughton, Timothy Pluard, Allison Creekmore, Zhanfang Guo, Jeremy Hoog, A. Craig Lockhart, Austin Doyle, Charles Erlichman, Matthew J. Ellis

    Published 2016
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  13. 13
    Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: a review of the National Cancer Database

    Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: a review of the National Cancer Database by Gregory Vlacich, Pamela Samson, Stephanie M. Perkins, Michael Roach, Parag J. Parikh, Jeffrey D. Bradley, A. Craig Lockhart, Varun Puri, Bryan F. Meyers, Benjamin D. Kozower, Clifford G. Robinson

    Published 2017
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  14. 14
    Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1

    Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1 by Lihong Wang-Bishop, Zheng Chen, Ahmed R. Gomaa, A. Craig Lockhart, Safia N. Salaria, Jialiang Wang, Keeli B. Lewis, Jeffrey Ecsedy, Kay Washington, R. Daniel Beauchamp, Wael El‐Rifai

    Published 2018
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  15. 15
    A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC-0994 in Patients with Advanced Solid Tumors

    A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC-0994 in Patients with Advanced Solid Tumors by Colin D. Weekes, A. Craig Lockhart, Patricia LoRusso, Elaine Murray, Erica Park, Mike Tagen, Jatinder Singh, Indrani Sarkar, Lars Müeller, Hatem Dokainish, Geoffrey I. Shapiro, Howard A. Burris

    Published 2020
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  16. 16
    Phase II study of neoadjuvant therapy with docetaxel, cisplatin, panitumumab, and radiation therapy followed by surgery in patients with locally advanced adenocarcinoma of the distal esophagus (ACOSOG Z4051)

    Phase II study of neoadjuvant therapy with docetaxel, cisplatin, panitumumab, and radiation therapy followed by surgery in patients with locally advanced adenocarcinoma of the dist... by A. Craig Lockhart, Carolyn E. Reed, Paul A. Decker, Bryan F. Meyers, Mark K. Ferguson, A.R. Oeltjen, Joe B. Putnam, Stephen D. Cassivi, Alberto J. Montero, Tracey E. Schefter

    Published 2014
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  17. 17
    Phase 1 Evaluation of [64Cu]DOTA-Patritumab to Assess Dosimetry, Apparent Receptor Occupancy, and Safety in Subjects with Advanced Solid Tumors

    Phase 1 Evaluation of [64Cu]DOTA-Patritumab to Assess Dosimetry, Apparent Receptor Occupancy, and Safety in Subjects with Advanced Solid Tumors by A. Craig Lockhart, Yongjian Liu, Farrokh Dehdashti, Richard Laforest, Joel Picus, Jennifer B. Frye, Lauren Trull, Stefanie Belanger, Madhuri Desai, Syed Mahmood, Jeanne Mendell, Michael J. Welch, Barry A. Siegel

    Published 2015
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  18. 18
    A phase I study of MK-5108, an oral aurora a kinase inhibitor, administered both as monotherapy and in combination with docetaxel, in patients with advanced or refractory solid tumors

    A phase I study of MK-5108, an oral aurora a kinase inhibitor, administered both as monotherapy and in combination with docetaxel, in patients with advanced or refractory solid tum... by Manik Amin, Susan Minton, Patricia LoRusso, Smitha Krishnamurthi, Cheryl A. Pickett, Jared Lunceford, Darcy A. Hille, David Mauro, Mark N. Stein, Andrea Wang‐Gillam, Lauren Trull, A. Craig Lockhart

    Published 2015
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  19. 19
    A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma

    A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma by Andrea Wang‐Gillam, Stacey M. Plambeck-Suess, Peter S. Goedegebuure, Peter O. Simon, Jonathan B. Mitchem, John R. Hornick, Steven Sorscher, Joel Picus, Rama Suresh, A. Craig Lockhart, Benjamin Tan, W. Hawkins

    Published 2012
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  20. 20
    Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer

    Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer by Venkataswarup Tiriveedhi, Natalia Tucker, John M. Herndon, Lijin Li, Mark Sturmoski, Matthew J. Ellis, X. Cynthia, Michael Naughton, A. Craig Lockhart, Feng Gao, Timothy P. Fleming, Peter S. Goedegebuure, Thalachallour Mohanakumar, William E. Gillanders

    Published 2014
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