Zoekresultaten - Crackower, Michael

Advances toward structure-based drug discovery for inflammasome targets door Wang, Li, Crackower, Michael A., Wu, Hao

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A Specific Role of Phosphatidylinositol 3–Kinase γ: A Regulation of Autonomic Ca(2)+ Oscillations in Cardiac Cells door Bony, Claire, Roche, Serge, Shuichi, Ueno, Sasaki, Takehiko, Crackower, Michael A., Penninger, Josef, Mano, Hiroyuki, Pucéat, Michel

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Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia door Nieuwenhuis, Erica, Motoyama, Jun, Barnfield, Paul C., Yoshikawa, Yoshiaki, Zhang, Xiaoyun, Mo, Rong, Crackower, Michael A., Hui, Chi-chung

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Loss of Angiotensin-Converting Enzyme-2 Leads to the Late Development of Angiotensin II-Dependent Glomerulosclerosis door Oudit, Gavin Y., Herzenberg, Andrew M., Kassiri, Zamaneh, Wong, Denise, Reich, Heather, Khokha, Rama, Crackower, Michael A., Backx, Peter H., Penninger, Josef M., Scholey, James W.

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Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene door Fourtounis, Jimmy, Wang, I-Ming, Mathieu, Marie-Claude, Claveau, David, Loo, Tenneille, Jackson, Aimee L, Peters, Mette A, Therien, Alex G, Boie, Yves, Crackower, Michael A

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Assessment of multiple pharmacological mechanisms in the ascaris sensitive sheep model of allergic asthma door Caniga, Michael, Woodhouse, Janice D, Wilhelm, Alan, Gil, Malgorzata A, McLeod, Robbie, Moy, Lily Y, Crackower, Michael A, Miller, Thomas, Abraham, William M, Cicmil, Milenko

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Inhibition of Immunoglobulin E signals during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells door Burton, Oliver T., Noval-Rivas, Magali, Zhou, Joseph S., Logsdon, Stephanie L., Darling, Alanna R., Koleoglou, Kyle J., Roers, Axel, Houshyar, Hani, Crackower, Michael A., Chatila, Talal A., Oettgen, Hans C.

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Phenotypic Responses of Differentiated Asthmatic Human Airway Epithelial Cultures to Rhinovirus door Bai, Jianwu, Smock, Steven L., Jackson, George R., MacIsaac, Kenzie D., Huang, Yongsheng, Mankus, Courtney, Oldach, Jonathan, Roberts, Brian, Ma, Yu-Lu, Klappenbach, Joel A., Crackower, Michael A., Alves, Stephen E., Hayden, Patrick J.

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Inhibition of spleen tyrosine kinase attenuates IgE‐mediated airway contraction and mediator release in human precision cut lung slices door Koziol‐White, Cynthia J, Jia, Yanlin, Baltus, Gretchen A, Cooper, Philip R, Zaller, Dennis M, Crackower, Michael A, Sirkowski, Erich E, Smock, Steven, Northrup, Alan B, Himes, Blanca E, Alves, Stephen E, Panettieri, Reynold A

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Angiotensin-converting enzyme 2 protects from severe acute lung failure door Imai, Yumiko, Kuba, Keiji, Rao, Shuan, Huan, Yi, Guo, Feng, Guan, Bin, Yang, Peng, Sarao, Renu, Wada, Teiji, Leong-Poi, Howard, Crackower, Michael A., Fukamizu, Akiyoshi, Hui, Chi-Chung, Hein, Lutz, Uhlig, Stefan, Slutsky, Arthur S., Jiang, Chengyu, Penninger, Josef M.

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Essential Role of Fkbp6 in Male Fertility and Homologous Chromosome Pairing in Meiosis door Crackower, Michael A., Kolas, Nadine K., Noguchi, Junko, Sarao, Renu, Kikuchi, Kazuhiro, Kaneko, Hiroyuki, Kobayashi, Eiji, Kawai, Yasuhiro, Kozieradzki, Ivona, Landers, Rushin, Mo, Rong, Hui, Chi-Chung, Nieves, Edward, Cohen, Paula E., Osborne, Lucy R., Wada, Teiji, Kunieda, Tetsuo, Moens, Peter B., Penninger, Josef M.

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Exploring the role of SYK in respiratory in vivo models door Caniga, Michael, Woodhouse, Janice D, Wilhelm, Alan, Gil, Malgorzata A, Jia, Yanlin, Yu, Hongshi, Vincent, Stella, Miller, Richard, Lieber, Gissela, Fernandez, Xiomara, Chapman, Richard, McLeod, Robbie, Moy, Lily Y, Kelly, Nancy, Hickey, Emily, Crackower, Michael A, Miller, Thomas, Abraham, William M, Cicmil, Milenko

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Genes related to emphysema are enriched for ubiquitination pathways door Stepaniants, Sergey, Wang, I-Ming, Boie, Yves, Mortimer, James, Kennedy, Brian, Elliott, Mark, Hayashi, Shizu, Luo, Honglin, Wong, Jerry, Loy, Leanna, Coulter, Silvija, Roberts, Christopher J, Hogg, James C, Sin, Don D, O’Neill, Gary, Crackower, Michael, Morris, Melody, Paré, Peter D, Obeidat, Ma’en

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A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system door St. Pierre, Cristina, Guo, Jane, Shin, John D., Engstrom, Laura W., Lee, Hyun-Hee, Herbert, Alan, Surdi, Laura, Baker, James, Salmon, Michael, Shah, Sanjiv, Ellis, J. Michael, Houshyar, Hani, Crackower, Michael A., Kleinschek, Melanie A., Jones, Dallas C., Hicks, Alexandra, Zaller, Dennis M., Alves, Stephen E., Ramadas, Ravisankar A.

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Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury door McCurley, Amy, Alimperti, Stella, Campos-Bilderback, Silvia B., Sandoval, Ruben M., Calvino, Jenna E., Reynolds, Taylor L., Quigley, Catherine, Mugford, Joshua W., Polacheck, William J., Gomez, Ivan G., Dovey, Jennifer, Marsh, Graham, Huang, Angela, Qian, Fang, Weinreb, Paul H., Dolinski, Brian M., Moore, Shaun, Duffield, Jeremy S., Chen, Christopher S., Molitoris, Bruce A., Violette, Shelia M., Crackower, Michael A.

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Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers door Wang, I-Ming, Zhang, Bin, Yang, Xia, Zhu, Jun, Stepaniants, Serguei, Zhang, Chunsheng, Meng, Qingying, Peters, Mette, He, Yudong, Ni, Chester, Slipetz, Deborah, Crackower, Michael A, Houshyar, Hani, Tan, Christopher M, Asante-Appiah, Ernest, O'Neill, Gary, Jane Luo, Mingjuan, Thieringer, Rolf, Yuan, Jeffrey, Chiu, Chi-Sung, Yee Lum, Pek, Lamb, John, Boie, Yves, Wilkinson, Hilary A, Schadt, Eric E, Dai, Hongyue, Roberts, Christopher

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