Výsledky vyhledávání - Crackower, Michael

Advances toward structure-based drug discovery for inflammasome targets Autor Wang, Li, Crackower, Michael A., Wu, Hao

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A Specific Role of Phosphatidylinositol 3–Kinase γ: A Regulation of Autonomic Ca(2)+ Oscillations in Cardiac Cells Autor Bony, Claire, Roche, Serge, Shuichi, Ueno, Sasaki, Takehiko, Crackower, Michael A., Penninger, Josef, Mano, Hiroyuki, Pucéat, Michel

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Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia Autor Nieuwenhuis, Erica, Motoyama, Jun, Barnfield, Paul C., Yoshikawa, Yoshiaki, Zhang, Xiaoyun, Mo, Rong, Crackower, Michael A., Hui, Chi-chung

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Loss of Angiotensin-Converting Enzyme-2 Leads to the Late Development of Angiotensin II-Dependent Glomerulosclerosis Autor Oudit, Gavin Y., Herzenberg, Andrew M., Kassiri, Zamaneh, Wong, Denise, Reich, Heather, Khokha, Rama, Crackower, Michael A., Backx, Peter H., Penninger, Josef M., Scholey, James W.

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Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene Autor Fourtounis, Jimmy, Wang, I-Ming, Mathieu, Marie-Claude, Claveau, David, Loo, Tenneille, Jackson, Aimee L, Peters, Mette A, Therien, Alex G, Boie, Yves, Crackower, Michael A

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Assessment of multiple pharmacological mechanisms in the ascaris sensitive sheep model of allergic asthma Autor Caniga, Michael, Woodhouse, Janice D, Wilhelm, Alan, Gil, Malgorzata A, McLeod, Robbie, Moy, Lily Y, Crackower, Michael A, Miller, Thomas, Abraham, William M, Cicmil, Milenko

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Inhibition of Immunoglobulin E signals during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells Autor Burton, Oliver T., Noval-Rivas, Magali, Zhou, Joseph S., Logsdon, Stephanie L., Darling, Alanna R., Koleoglou, Kyle J., Roers, Axel, Houshyar, Hani, Crackower, Michael A., Chatila, Talal A., Oettgen, Hans C.

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Phenotypic Responses of Differentiated Asthmatic Human Airway Epithelial Cultures to Rhinovirus Autor Bai, Jianwu, Smock, Steven L., Jackson, George R., MacIsaac, Kenzie D., Huang, Yongsheng, Mankus, Courtney, Oldach, Jonathan, Roberts, Brian, Ma, Yu-Lu, Klappenbach, Joel A., Crackower, Michael A., Alves, Stephen E., Hayden, Patrick J.

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Inhibition of spleen tyrosine kinase attenuates IgE‐mediated airway contraction and mediator release in human precision cut lung slices Autor Koziol‐White, Cynthia J, Jia, Yanlin, Baltus, Gretchen A, Cooper, Philip R, Zaller, Dennis M, Crackower, Michael A, Sirkowski, Erich E, Smock, Steven, Northrup, Alan B, Himes, Blanca E, Alves, Stephen E, Panettieri, Reynold A

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Angiotensin-converting enzyme 2 protects from severe acute lung failure Autor Imai, Yumiko, Kuba, Keiji, Rao, Shuan, Huan, Yi, Guo, Feng, Guan, Bin, Yang, Peng, Sarao, Renu, Wada, Teiji, Leong-Poi, Howard, Crackower, Michael A., Fukamizu, Akiyoshi, Hui, Chi-Chung, Hein, Lutz, Uhlig, Stefan, Slutsky, Arthur S., Jiang, Chengyu, Penninger, Josef M.

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Essential Role of Fkbp6 in Male Fertility and Homologous Chromosome Pairing in Meiosis Autor Crackower, Michael A., Kolas, Nadine K., Noguchi, Junko, Sarao, Renu, Kikuchi, Kazuhiro, Kaneko, Hiroyuki, Kobayashi, Eiji, Kawai, Yasuhiro, Kozieradzki, Ivona, Landers, Rushin, Mo, Rong, Hui, Chi-Chung, Nieves, Edward, Cohen, Paula E., Osborne, Lucy R., Wada, Teiji, Kunieda, Tetsuo, Moens, Peter B., Penninger, Josef M.

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Exploring the role of SYK in respiratory in vivo models Autor Caniga, Michael, Woodhouse, Janice D, Wilhelm, Alan, Gil, Malgorzata A, Jia, Yanlin, Yu, Hongshi, Vincent, Stella, Miller, Richard, Lieber, Gissela, Fernandez, Xiomara, Chapman, Richard, McLeod, Robbie, Moy, Lily Y, Kelly, Nancy, Hickey, Emily, Crackower, Michael A, Miller, Thomas, Abraham, William M, Cicmil, Milenko

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Genes related to emphysema are enriched for ubiquitination pathways Autor Stepaniants, Sergey, Wang, I-Ming, Boie, Yves, Mortimer, James, Kennedy, Brian, Elliott, Mark, Hayashi, Shizu, Luo, Honglin, Wong, Jerry, Loy, Leanna, Coulter, Silvija, Roberts, Christopher J, Hogg, James C, Sin, Don D, O’Neill, Gary, Crackower, Michael, Morris, Melody, Paré, Peter D, Obeidat, Ma’en

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A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system Autor St. Pierre, Cristina, Guo, Jane, Shin, John D., Engstrom, Laura W., Lee, Hyun-Hee, Herbert, Alan, Surdi, Laura, Baker, James, Salmon, Michael, Shah, Sanjiv, Ellis, J. Michael, Houshyar, Hani, Crackower, Michael A., Kleinschek, Melanie A., Jones, Dallas C., Hicks, Alexandra, Zaller, Dennis M., Alves, Stephen E., Ramadas, Ravisankar A.

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Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury Autor McCurley, Amy, Alimperti, Stella, Campos-Bilderback, Silvia B., Sandoval, Ruben M., Calvino, Jenna E., Reynolds, Taylor L., Quigley, Catherine, Mugford, Joshua W., Polacheck, William J., Gomez, Ivan G., Dovey, Jennifer, Marsh, Graham, Huang, Angela, Qian, Fang, Weinreb, Paul H., Dolinski, Brian M., Moore, Shaun, Duffield, Jeremy S., Chen, Christopher S., Molitoris, Bruce A., Violette, Shelia M., Crackower, Michael A.

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Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers Autor Wang, I-Ming, Zhang, Bin, Yang, Xia, Zhu, Jun, Stepaniants, Serguei, Zhang, Chunsheng, Meng, Qingying, Peters, Mette, He, Yudong, Ni, Chester, Slipetz, Deborah, Crackower, Michael A, Houshyar, Hani, Tan, Christopher M, Asante-Appiah, Ernest, O'Neill, Gary, Jane Luo, Mingjuan, Thieringer, Rolf, Yuan, Jeffrey, Chiu, Chi-Sung, Yee Lum, Pek, Lamb, John, Boie, Yves, Wilkinson, Hilary A, Schadt, Eric E, Dai, Hongyue, Roberts, Christopher

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