Search Results - Constantinos Demetriades

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  1. 1
    The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging

    The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging by Stephanie Fernandes, Constantinos Demetriades

    Published 2021
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  2. 2
    Unbiased evaluation of rapamycin's specificity as an <scp>mTOR</scp> inhibitor

    Unbiased evaluation of rapamycin's specificity as an <scp>mTOR</scp> inhibitor by Filippo Artoni, Nina Grützmacher, Constantinos Demetriades

    Published 2023
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  3. 3
    Regulation of TORC1 in Response to Amino Acid Starvation via Lysosomal Recruitment of TSC2

    Regulation of TORC1 in Response to Amino Acid Starvation via Lysosomal Recruitment of TSC2 by Constantinos Demetriades, Nikolaos Doumpas, Aurelio A. Teleman

    Published 2014
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  4. 4
    Lysosomal recruitment of TSC2 is a universal response to cellular stress

    Lysosomal recruitment of TSC2 is a universal response to cellular stress by Constantinos Demetriades, Monika Plescher, Aurelio A. Teleman

    Published 2016
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  5. 5
    CycD/Cdk4 and Discontinuities in Dpp Signaling Activate TORC1 in the Drosophila Wing Disc

    CycD/Cdk4 and Discontinuities in Dpp Signaling Activate TORC1 in the Drosophila Wing Disc by Jesús Romero‐Pozuelo, Constantinos Demetriades, Phillip Schroeder, Aurelio A. Teleman

    Published 2017
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  6. 6
    A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

    A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids by Peter Gollwitzer, Nina Grützmacher, Sabine Wilhelm, Daniel Kümmel, Constantinos Demetriades

    Published 2022
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  7. 7
    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress by Julian Nüchel, Marina Tauber, Janica L. Nolte, Matthias Mörgelin, Clara Türk, Beate Eckes, Constantinos Demetriades, Markus Plomann

    Published 2021
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  8. 8
    Spatial and functional separation of mTORC1 signalling in response to different amino acid sources

    Spatial and functional separation of mTORC1 signalling in response to different amino acid sources by Stephanie Fernandes, Danai-Dimitra Angelidaki, Julian Nüchel, Jiyoung Pan, Peter Gollwitzer, Yoav Elkis, Filippo Artoni, Sabine Wilhelm, Marija Kovacevic-Sarmiento, Constantinos Demetriades

    Published 2024
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  9. 9
    Genomic Analysis Reveals a Novel Nuclear Factor-κB (NF-κB)-binding Site in Alu-repetitive Elements

    Genomic Analysis Reveals a Novel Nuclear Factor-κB (NF-κB)-binding Site in Alu-repetitive Elements by Athina Antonaki, Constantinos Demetriades, Alexander Polyzos, Aggelos Banos, Giannis Vatsellas, Matthieu D. Lavigne, Effie Apostolou, Eva Mantouvalou, Deppie Papadopoulou, George Mosialos, Dimitris Thanos

    Published 2011
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  10. 10
    <scp>mTORC1</scp> activity negatively regulates human hair follicle growth and pigmentation

    <scp>mTORC1</scp> activity negatively regulates human hair follicle growth and pigmentation by Takahiro Suzuki, Jérémy Chéret, FERNANDA DINELLI SCALA, Aysun Akhundlu, Jennifer Gherardini, Dana‐Lee Demetrius, James D.B. O’Sullivan, Gorana Kuka Epstein, Alan J. Bauman, Constantinos Demetriades, Ralf Paus

    Published 2023
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  11. 11
    Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor

    Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor by Raffaele Nicastro, Laura Brohée, Josephine Alba, Julian Nüchel, Gianluca Figlia, Stefanie Kipschull, Peter Gollwitzer, Jesús Romero‐Pozuelo, Stephanie Fernandes, Andreas Lamprakis, Stefano Vanni, Aurelio A. Teleman, Claudio De Virgilio, Constantinos Demetriades

    Published 2023
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  12. 12
    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation

    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation by Katharina Fitzian, Anne Brückner, Laura Brohée, Reinhard Zech, Claudia Antoni, Stephan Kiontke, Raphael Gasper, Anna L. L. Matos, Stephanie Beel, Sabine Wilhelm, Volker Gerke, Christian Ungermann, Mark Nellist, Stefan Raunser, Constantinos Demetriades, Andrea Oeckinghaus, Daniel Kümmel

    Published 2021
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  13. 13
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling by Mirja Tamara Prentzell, Ulrike Rehbein, Marti Cadena Sandoval, Ann‐Sofie De Meulemeester, Ralf Baumeister, Laura Brohée, Bianca Berdel, Mathias Bockwoldt, Bernadette Carroll, Suvagata Roy Chowdhury, Andreas von Deimling, Constantinos Demetriades, Gianluca Figlia, Mariana E. G. de Araújo, Alexander Martin Heberle, Ines Heiland, Birgit Holzwarth, Lukas A. Huber, Jacek Jaworski, Magdalena Kedra, Katharina Kern, Andrii Kopach, Viktor I. Korolchuk, Ineke Kuper, Matylda Macias, Mark Nellist, Wilhelm Palm, Stefan Pusch, José M. Ramos Pittol, Michèle Reil, Anja Reintjes, Friederike Reuter, Julian R. Sampson, Chloë Scheldeman, Aleksandra Siekierska, Eduard Stefan, Aurelio A. Teleman, Laura E. Thomas, Omar Torres‐Quesada, Saskia Trump, Hannah D. West, Peter de Witte, Sandra Woltering, Teodor E. Yordanov, Justyna Zmorzyńska, Christiane A. Opitz, Kathrin Thedieck

    Published 2021
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