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From innovation to application: Social–ecological context, diagnostics, drugs and integrated control of schistosomiasis 著者: Jürg Utzinger, Eliézer K. N’Goran, Conor R. Caffrey, Jennifer Keiser

出版事項 2010

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Targeting proteasomes in infectious organisms to combat disease 著者: Betsaida Bibo‐Verdugo, Zhenze Jiang, Conor R. Caffrey, Anthony J. O’Donoghue

出版事項 2017

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Revisão

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Proteomic Identification of IPSE/alpha-1 as a Major Hepatotoxin Secreted by Schistosoma mansoni Eggs 著者: Maha‐Hamadien Abdulla, Kee‐Chong Lim, James H. McKerrow, Conor R. Caffrey

出版事項 2011

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Artigo

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Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor 著者: Maha‐Hamadien Abdulla, Kee‐Chong Lim, Mohammed Sajid, James H. McKerrow, Conor R. Caffrey

出版事項 2007

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Artigo

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5

Chemical and Genetic Validation of the Statin Drug Target to Treat the Helminth Disease, Schistosomiasis 著者: Liliana Rojo‐Arreola, Thavy Long, Daniel Asarnow, Brian M. Suzuki, Rahul Singh, Conor R. Caffrey

出版事項 2014

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Artigo

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Profiling of proteolytic enzymes in the gut of the tick Ixodes ricinus reveals an evolutionarily conserved network of aspartic and cysteine peptidases 著者: Daniel Sojka, Zdeněk Franta, Martin Horn, Ondřej Hajdušek, Conor R. Caffrey, Michael A. Mares, Petr Kopáček

出版事項 2008

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Artigo

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Cysteine proteases during larval migration and development of helminths in their final host 著者: Alexandra Grote, Conor R. Caffrey, Karina M. Rebello, David W. Smith, John P. Dalton, Sara Lustigman

出版事項 2018

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Revisão

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8

Aryl ureas represent a new class of anti-trypanosomal agents 著者: Xiaohui Du, Elizabeth Hansell, Juan C. Engel, Conor R. Caffrey, Fred E. Cohen, James H. McKerrow

出版事項 2000

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Artigo

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9

A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni 著者: Conor R. Caffrey, Andreas Rohwer, Frank Oellien, Richard J. Marhöfer, Bryony Braschi, Guilherme Oliveira, James H. McKerrow, Paul M. Selzer

出版事項 2009

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Artigo

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10

A single-cell RNA-seq atlas of <i>Schistosoma mansoni</i> identifies a key regulator of blood feeding 著者: George Wendt, Lu Zhao, Rui Chen, Chenxi Liu, Anthony J. O’Donoghue, Conor R. Caffrey, Michael L. Reese, James J. Collins

出版事項 2020

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Artigo

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11

Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis 著者: Hyokyeong Lee, Asher Moody-Davis, Utsab Saha, Brian M. Suzuki, Daniel Asarnow, Steven Chen, Michelle R. Arkin, Conor R. Caffrey, Rahul Singh

出版事項 2012

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Artigo

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12

A Multienzyme Network Functions in Intestinal Protein Digestion by a Platyhelminth Parasite 著者: Melaine Delcroix, Mohammed Sajid, Conor R. Caffrey, Kee-C Lim, Jan Dvořák, Ivy Hsieh, Mahmoud Mohamed Bahgat, Colette Dissous, James H. McKerrow

出版事項 2006

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Artigo

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13

Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection 著者: Lúcia Alves de Oliveira Fraga, Erika Lamb, Elizabeth Castro Moreno, Mitali Chatterjee, Jan Dvořák, Melaine Delcroix, Mohammed Sajid, Conor R. Caffrey, Stephen J. Davies

出版事項 2010

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Artigo

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14

Hemoglobin Digestion in Blood-Feeding Ticks: Mapping a Multipeptidase Pathway by Functional Proteomics 著者: Martin Horn, Martina Nussbaumerová, Miloslav Šanda, Zuzana Kovářová, Jindřich Srba, Zdeněk Franta, Daniel Sojka, Matthew Bogyo, Conor R. Caffrey, Petr Kopáček, Michael A. Mares

出版事項 2009

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Artigo

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15

Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni 著者: Adéla Jílková, Pavlína Řezáčová, Martin Lepšı́k, Martin Horn, Jana Váchová, Jindřich Fanfrlík, J. Brynda, James H. McKerrow, Conor R. Caffrey, Michael A. Mares

出版事項 2011

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Artigo

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16

Evaluation of the CCA Immuno-Chromatographic Test to Diagnose Schistosoma mansoni in Minas Gerais State, Brazil 著者: Alda Maria Soares Silveira, Emanuele Gama Dutra Costa, Debalina Ray, Brian M. Suzuki, Michael H. Hsieh, Lúcia Alves de Oliveira Fraga, Conor R. Caffrey

出版事項 2016

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Artigo

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17

High Throughput and Computational Repurposing for Neglected Diseases 著者: H. Hernandez, Melinda Soeung, Kimberley M. Zorn, Norah E Ashoura, Melina Mottin, Carolina Horta Andrade, Conor R. Caffrey, Jair L. Siqueira-Neto, Sean Ekins

出版事項 2018

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Revisão

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18

Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors 著者: Pavla Fajtová, Saša Štefanić, Martin Hradílek, Jan Dvořák, Jiřı́ Vondrášek, Adéla Jílková, Lenka Ulrychová, James H. McKerrow, Conor R. Caffrey, Michael A. Mares, Martin Horn

出版事項 2015

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Artigo

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19

Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening 著者: Maha-Hamadien Abdulla, Debbie S. Ruelas, Brian Wolff, June Snedecor, Kee‐Chong Lim, Fengyun Xu, Adam R. Renslo, Janice A. Williams, James H. McKerrow, Conor R. Caffrey

出版事項 2009

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Artigo

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20

A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition 著者: Theresa C. O’Brien, Zachary B. Mackey, Richard D. Fetter, Youngchool Choe, Anthony J. O’Donoghue, Min Zhou, Charles S. Craik, Conor R. Caffrey, James H. McKerrow

出版事項 2008

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Artigo

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検索結果 - Conor R. Caffrey

From innovation to application: Social–ecological context, diagnostics, drugs and integrated control of schistosomiasis 著者: Jürg Utzinger, Eliézer K. N’Goran, Conor R. Caffrey, Jennifer Keiser

Targeting proteasomes in infectious organisms to combat disease 著者: Betsaida Bibo‐Verdugo, Zhenze Jiang, Conor R. Caffrey, Anthony J. O’Donoghue

Proteomic Identification of IPSE/alpha-1 as a Major Hepatotoxin Secreted by Schistosoma mansoni Eggs 著者: Maha‐Hamadien Abdulla, Kee‐Chong Lim, James H. McKerrow, Conor R. Caffrey

Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor 著者: Maha‐Hamadien Abdulla, Kee‐Chong Lim, Mohammed Sajid, James H. McKerrow, Conor R. Caffrey

Chemical and Genetic Validation of the Statin Drug Target to Treat the Helminth Disease, Schistosomiasis 著者: Liliana Rojo‐Arreola, Thavy Long, Daniel Asarnow, Brian M. Suzuki, Rahul Singh, Conor R. Caffrey

Profiling of proteolytic enzymes in the gut of the tick Ixodes ricinus reveals an evolutionarily conserved network of aspartic and cysteine peptidases 著者: Daniel Sojka, Zdeněk Franta, Martin Horn, Ondřej Hajdušek, Conor R. Caffrey, Michael A. Mares, Petr Kopáček

Cysteine proteases during larval migration and development of helminths in their final host 著者: Alexandra Grote, Conor R. Caffrey, Karina M. Rebello, David W. Smith, John P. Dalton, Sara Lustigman

Aryl ureas represent a new class of anti-trypanosomal agents 著者: Xiaohui Du, Elizabeth Hansell, Juan C. Engel, Conor R. Caffrey, Fred E. Cohen, James H. McKerrow

A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni 著者: Conor R. Caffrey, Andreas Rohwer, Frank Oellien, Richard J. Marhöfer, Bryony Braschi, Guilherme Oliveira, James H. McKerrow, Paul M. Selzer

A single-cell RNA-seq atlas of <i>Schistosoma mansoni</i> identifies a key regulator of blood feeding 著者: George Wendt, Lu Zhao, Rui Chen, Chenxi Liu, Anthony J. O’Donoghue, Conor R. Caffrey, Michael L. Reese, James J. Collins

Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis 著者: Hyokyeong Lee, Asher Moody-Davis, Utsab Saha, Brian M. Suzuki, Daniel Asarnow, Steven Chen, Michelle R. Arkin, Conor R. Caffrey, Rahul Singh

A Multienzyme Network Functions in Intestinal Protein Digestion by a Platyhelminth Parasite 著者: Melaine Delcroix, Mohammed Sajid, Conor R. Caffrey, Kee-C Lim, Jan Dvořák, Ivy Hsieh, Mahmoud Mohamed Bahgat, Colette Dissous, James H. McKerrow

Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection 著者: Lúcia Alves de Oliveira Fraga, Erika Lamb, Elizabeth Castro Moreno, Mitali Chatterjee, Jan Dvořák, Melaine Delcroix, Mohammed Sajid, Conor R. Caffrey, Stephen J. Davies

Hemoglobin Digestion in Blood-Feeding Ticks: Mapping a Multipeptidase Pathway by Functional Proteomics 著者: Martin Horn, Martina Nussbaumerová, Miloslav Šanda, Zuzana Kovářová, Jindřich Srba, Zdeněk Franta, Daniel Sojka, Matthew Bogyo, Conor R. Caffrey, Petr Kopáček, Michael A. Mares

Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni 著者: Adéla Jílková, Pavlína Řezáčová, Martin Lepšı́k, Martin Horn, Jana Váchová, Jindřich Fanfrlík, J. Brynda, James H. McKerrow, Conor R. Caffrey, Michael A. Mares

Evaluation of the CCA Immuno-Chromatographic Test to Diagnose Schistosoma mansoni in Minas Gerais State, Brazil 著者: Alda Maria Soares Silveira, Emanuele Gama Dutra Costa, Debalina Ray, Brian M. Suzuki, Michael H. Hsieh, Lúcia Alves de Oliveira Fraga, Conor R. Caffrey

High Throughput and Computational Repurposing for Neglected Diseases 著者: H. Hernandez, Melinda Soeung, Kimberley M. Zorn, Norah E Ashoura, Melina Mottin, Carolina Horta Andrade, Conor R. Caffrey, Jair L. Siqueira-Neto, Sean Ekins

A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition 著者: Theresa C. O’Brien, Zachary B. Mackey, Richard D. Fetter, Youngchool Choe, Anthony J. O’Donoghue, Min Zhou, Charles S. Craik, Conor R. Caffrey, James H. McKerrow

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