Résultats de la recherche - Conor R. Caffrey
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Profiling of proteolytic enzymes in the gut of the tick Ixodes ricinus reveals an evolutionarily conserved network of aspartic and cysteine peptidases par Daniel Sojka, Zdeněk Franta, Martin Horn, Ondřej Hajdušek, Conor R. Caffrey, Michael A. Mares, Petr Kopáček
Publié 2008Artigo -
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A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni par Conor R. Caffrey, Andreas Rohwer, Frank Oellien, Richard J. Marhöfer, Bryony Braschi, Guilherme Oliveira, James H. McKerrow, Paul M. Selzer
Publié 2009Artigo -
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Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis par Hyokyeong Lee, Asher Moody-Davis, Utsab Saha, Brian M. Suzuki, Daniel Asarnow, Steven Chen, Michelle R. Arkin, Conor R. Caffrey, Rahul Singh
Publié 2012Artigo -
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A Multienzyme Network Functions in Intestinal Protein Digestion by a Platyhelminth Parasite par Melaine Delcroix, Mohammed Sajid, Conor R. Caffrey, Kee-C Lim, Jan Dvořák, Ivy Hsieh, Mahmoud Mohamed Bahgat, Colette Dissous, James H. McKerrow
Publié 2006Artigo -
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Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection par Lúcia Alves de Oliveira Fraga, Erika Lamb, Elizabeth Castro Moreno, Mitali Chatterjee, Jan Dvořák, Melaine Delcroix, Mohammed Sajid, Conor R. Caffrey, Stephen J. Davies
Publié 2010Artigo -
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Hemoglobin Digestion in Blood-Feeding Ticks: Mapping a Multipeptidase Pathway by Functional Proteomics par Martin Horn, Martina Nussbaumerová, Miloslav Šanda, Zuzana Kovářová, Jindřich Srba, Zdeněk Franta, Daniel Sojka, Matthew Bogyo, Conor R. Caffrey, Petr Kopáček, Michael A. Mares
Publié 2009Artigo -
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Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni par Adéla Jílková, Pavlína Řezáčová, Martin Lepšı́k, Martin Horn, Jana Váchová, Jindřich Fanfrlík, J. Brynda, James H. McKerrow, Conor R. Caffrey, Michael A. Mares
Publié 2011Artigo -
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Evaluation of the CCA Immuno-Chromatographic Test to Diagnose Schistosoma mansoni in Minas Gerais State, Brazil par Alda Maria Soares Silveira, Emanuele Gama Dutra Costa, Debalina Ray, Brian M. Suzuki, Michael H. Hsieh, Lúcia Alves de Oliveira Fraga, Conor R. Caffrey
Publié 2016Artigo -
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High Throughput and Computational Repurposing for Neglected Diseases par H. Hernandez, Melinda Soeung, Kimberley M. Zorn, Norah E Ashoura, Melina Mottin, Carolina Horta Andrade, Conor R. Caffrey, Jair L. Siqueira-Neto, Sean Ekins
Publié 2018Revisão -
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Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors par Pavla Fajtová, Saša Štefanić, Martin Hradílek, Jan Dvořák, Jiřı́ Vondrášek, Adéla Jílková, Lenka Ulrychová, James H. McKerrow, Conor R. Caffrey, Michael A. Mares, Martin Horn
Publié 2015Artigo -
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Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening par Maha-Hamadien Abdulla, Debbie S. Ruelas, Brian Wolff, June Snedecor, Kee‐Chong Lim, Fengyun Xu, Adam R. Renslo, Janice A. Williams, James H. McKerrow, Conor R. Caffrey
Publié 2009Artigo -
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A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition par Theresa C. O’Brien, Zachary B. Mackey, Richard D. Fetter, Youngchool Choe, Anthony J. O’Donoghue, Min Zhou, Charles S. Craik, Conor R. Caffrey, James H. McKerrow
Publié 2008Artigo
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Cysteine protease
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Schistosoma
Bioinformatics
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Parasite hosting
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