検索結果 - Colleen M. Niswender
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Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery 著者: Bruce J. Melancon, Corey R. Hopkins, Michael R. Wood, Kyle A. Emmitte, Colleen M. Niswender, Arthur Christopoulos, P. Jeffrey Conn, Craig W. Lindsley
出版事項 2011Artigo -
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A Novel Class of Succinimide-Derived Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 1 Provides Insight into a Disconnect in Activity between the Rat and... 著者: Hyekyung P. Cho, Darren W. Engers, Daryl F. Venable, Colleen M. Niswender, Craig W. Lindsley, P. Jeffrey Conn, Kyle A. Emmitte, Alice L. Rodriguez
出版事項 2014Artigo -
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Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs) 著者: Darren W. Engers, Colleen M. Niswender, C. David Weaver, Satyawan Jadhav, Usha N. Menon, Rocio Zamorano, P. Jeffrey Conn, Craig W. Lindsley, Corey R. Hopkins
出版事項 2009Artigo
関連主題
Receptor
Biology
Neuroscience
Biochemistry
Allosteric regulation
Chemistry
Pharmacology
Allosteric modulator
Glutamate receptor
Metabotropic glutamate receptor
Medicine
Metabotropic receptor
Psychology
Agonist
Internal medicine
Metabotropic glutamate receptor 5
Muscarinic acetylcholine receptor
Psychiatry
Metabotropic glutamate receptor 1
Genetics
Metabotropic glutamate receptor 2
Schizophrenia (object-oriented programming)
Acetylcholine
Dopamine
Drug discovery
In vivo
Muscarinic acetylcholine receptor M1
NMDA receptor
Cognition
Long-term potentiation