Search Results - Colin W. Ward
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Structural Determinants for High-Affinity Binding of Insulin-Like Growth Factor II to Insulin Receptor (IR)-A, the Exon 11 Minus Isoform of the IR by Adam Denley, Eric R. Bonython, Grant W. Booker, Leah Cosgrove, Briony E. Forbes, Colin W. Ward, John C. Wallace
Published 2004Artigo -
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An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors by Antony W. Burgess, Hyun‐Soo Cho, Charles Eigenbrot, Kathryn M. Ferguson, Thomas P.J. Garrett, Daniel J. Leahy, Mark A. Lemmon, Mark X. Sliwkowski, Colin W. Ward, Shigeyuki Yokoyama
Published 2003Revisão -
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The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity by Meizhen Lou, Thomas P.J. Garrett, Neil M. McKern, Peter A. Hoyne, V. Chandana Epa, John D. Bentley, George O. Lovrecz, Leah Cosgrove, Maurice J. Frenkel, Colin W. Ward
Published 2006Artigo -
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The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors by Thomas P.J. Garrett, Neil M. McKern, Meizhen Lou, T C Elleman, Timothy E. Adams, George O. Lovrecz, Michael Kofler, Robert N. Jorissen, Edouard C. Nice, Antony W. Burgess, Colin W. Ward
Published 2003Artigo -
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Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists by Brian J. Smith, Kun Huang, G.K.-W. Kong, Shu Jin Chan, Satoe H. Nakagawa, John G. Menting, Shi-Quan Hu, Jonathan Whittaker, Donald F. Steiner, Panayotis G. Katsoyannis, Colin W. Ward, Michael A. Weiss, Michael C. Lawrence
Published 2010Artigo -
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Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor α by Thomas P.J. Garrett, Neil M. McKern, Meizhen Lou, T C Elleman, Timothy E. Adams, George O. Lovrecz, Hong‐Jian Zhu, Francesca Walker, M. J. Frenkel, Peter A. Hoyne, Robert N. Jorissen, Edouard C. Nice, Antony W. Burgess, Colin W. Ward
Published 2002Artigo -
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CR1/CR2 Interactions Modulate the Functions of the Cell Surface Epidermal Growth Factor Receptor by Francesca Walker, Suzanne G. Orchard, Robert N. Jorissen, Nathan E. Hall, Huihua Zhang, Peter A. Hoyne, Timothy E. Adams, Terrance G. Johns, Colin W. Ward, Thomas P.J. Garrett, Hong‐Jian Zhu, Maureen Nerrie, Andrew M. Scott, Edouard C. Nice, Antony W. Burgess
Published 2004Artigo -
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How insulin engages its primary binding site on the insulin receptor by John G. Menting, Jonathan Whittaker, Mai B. Margetts, Linda Whittaker, G.K.-W. Kong, Brian J. Smith, Christopher J.E. Watson, Lenka Žáková, Emília Kletvíková, Jiřı́ Jiráček, Shu Jin Chan, Donald F. Steiner, Guy Dodson, A.M. Brzozowski, Michael A. Weiss, Colin W. Ward, Michael C. Lawrence
Published 2013Artigo -
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Identification of the Epitope for the Epidermal Growth Factor Receptor-specific Monoclonal Antibody 806 Reveals That It Preferentially Recognizes an Untethered Form of the Receptor by Terrance G. Johns, Timothy E. Adams, Jennifer R. Cochran, Nathan E. Hall, Peter A. Hoyne, Mark Olsen, Yong‐Sung Kim, Julie Rothacker, Edouard C. Nice, Francesca Walker, Gerd Ritter, Achim A. Jungbluth, Lloyd J. Old, Colin W. Ward, Antony W. Burgess, K. Dane Wittrup, Andrew M. Scott
Published 2004Artigo -
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Protective hinge in insulin opens to enable its receptor engagement by John G. Menting, Yanwu Yang, Shu Jin Chan, Nelson B. Phillips, Brian J. Smith, Jonathan Whittaker, Nalinda P. Wickramasinghe, Linda Whittaker, Vijay Pandyarajan, Zhu‐li Wan, Satya P. Yadav, Julie M. Carroll, Natalie Strokes, Charles T. Roberts, Faramarz Ismail‐Beigi, Wieslawa Milewski, Donald F. Steiner, Virander S. Chauhan, Colin W. Ward, Michael A. Weiss, Michael C. Lawrence
Published 2014Artigo
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Biology
Receptor
Biochemistry
Cell biology
Chemistry
Endocrinology
Growth factor
Insulin
Insulin receptor
Insulin resistance
Ectodomain
Epidermal growth factor receptor
Gene
Ligand (biochemistry)
Biophysics
Epidermal growth factor
Growth factor receptor
Receptor tyrosine kinase
Signal transduction
Genetics
Insulin-like growth factor
Insulin-like growth factor 1 receptor
Stereochemistry
Tyrosine kinase
Amino acid
Binding site
Botany
Cancer research
Computational biology
Crystallography