Resultados da pesquisa - Cloughesy, Tim

ACTR-18. PHASE II TRIAL OF TEMOZOLOMIDE AND TRC 102, BASE EXCISION REPAIR INHIBITOR, IN BEVACIZUMAB NAÏVE GLIOBLASTOMA AT FIRST RECURRENCE Por Ahluwalia, Manmeet, Drappatz, Jan, Ye, Xiaobu, Walbert, Tobias, Holdhoff, Matthias, Lesser, Glenn, Cloughesy, Tim, Peereboom, David, Burt Nabors, L, Wen, Patrick, Grossman, Stuart, Rogers, Lisa

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A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: A North American Brain Tumor Consortium (NABTC01-05) Por Butowski, Nicholas, Chang, Susan M., Junck, Larry, DeAngelis, Lisa M., Abrey, Lauren, Fink, Karen, Cloughesy, Tim, Lamborn, Kathleen R., Salazar, Andres M., Prados, Michael D.

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ATIM-38. PHASE 2 STUDY TO EVALUATE THE CLINICAL EFFICACY AND SAFETY OF MEDI4736 (DURVALUMAB, DURVA) + BEVACIZUMAB (BEV) IN BEV-NAÏVE PATIENTS WITH RECURRENT GLIOBLASTOMA (GBM) Por Reardon, David, Kaley, Thomas, Dietrich, Jorg, Clarke, Jennifer, Dunn, Gavin, Lim, Michael, Cloughesy, Tim, Gan, Hui, Park, Andrew, Schwarzenberger, Paul, Ricciardi, Toni, Macri, Mary, Ryan, Aileen, Venhaus, Ralph

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ATIM-39. IMPROVED SURVIVAL NOTED IN GLIOBLASTOMA PATIENTS TREATED WITH ADJUVANT TLR-3 AGONIST IN SETTING OF AUTOLOGOUS LYSATE-PULSED DC VACCINATION Por Antonios, Joseph, Everson, Richard, Soto, Horacio, Khattab, Sara, Bethel, Jacob, Sun, Matthew, Mochizuki, Aaron, Lee, Alexander, Odesa, Sylvia, Billingslea-Yoon, Emma, Moughon, Diana, Wang, Anthony, Cloughesy, Tim, Prins, Robert, Liau, Linda

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AT-18 SURVIVAL ANALYSIS OF PATIENTS WITH A PFS EVENT WHO DID NOT RECEIVE POST-PROGRESSION THERAPY IN AVAGLIO (BEVACIZUMAB [BEV] PLUS RADIOTHERAPY [RT] AND TEMOZOLOMIDE [TMZ] FOR NE... Por Cloughesy, Tim, Wick, Wolfgang, Mason, Warren, Henriksson, Roger, Saran, Frank, Nishikawa, Ryo, Carpentier, Antoine F., Hoang-Xuan, Khe, Kavan, Petr, Cernea, Dana, Brandes, Alba A., Revil, Cedric, Abrey, Lauren, Chinot, Olivier L.

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ET-12 PHASE II STUDY OF ONARTUZUMAB PLUS BEVACIZUMAB VERSUS PLACEBO PLUS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA Por Cloughesy, Tim, Finocchiaro, Gaetano, Belda-Iniesta, Cristobel, Recht, Lawrence, Brandes, Alba A, Pineda, Estela, Mikkelsen, Tom, Chinot, Olivier, Balana, Carmen, Macdonald, David, Westphal, Manfred, Hopkins, Kirsten, Weller, Michael, Bruey, Jean-Marie, Liu, Bo, Verret, Wendy

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Phase II Study of Bortezomib in Combination with Temozolomide and Regional Radiation Therapy for Upfront Treatment of Patients with Newly-Diagnosed Glioblastoma Multiforme: Safety... Por Kong, Xiao-Tang, Nguyen, Nhung T., Choi, Yoon J., Zhang, Guicheng, Nguyen, HuyTram N., Filka, Emese, Green, Stacey, Yong, William H., Liau, Linda M., Green, Richard M., Kaprealian, Tania, Pope, Whitney B., Nghiemphu, P. Leia, Cloughesy, Tim, Lassman, Andrew, Lai, Albert

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Myeloid Biomarkers Associated with Glioblastoma Response to Anti-Vascular Endothelial Growth Factor Therapy with Aflibercept Por de Groot, John F, Piao, Yuji, Tran, Hai, Gilbert, Mark, Wu, Hua-Kang, Liu, Jun, Bekele, B. Nebiyou, Cloughesy, Tim, Mehta, Minesh, Robins, H. Ian, Lassman, Andrew, DeAngelis, Lisa, Camphausen, Kevin, Chen, Alice, Yung, WKA, Prados, Michael, Wen, Patrick Y., Heymach, John V

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First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy Por Munster, Pamela, Mita, Monica, Mahipal, Amit, Nemunaitis, John, Massard, Christophe, Mikkelsen, Tom, Cruz, Cristina, Paz-Ares, Luis, Hidalgo, Manuel, Rathkopf, Dana, Blumenschein Jr, George, Smith, David C, Eichhorst, Barbara, Cloughesy, Tim, Filvaroff, Ellen H, Li, Shaoyi, Raymon, Heather, de Haan, Hans, Hege, Kristen, Bendell, Johanna C

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Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma Por Cloughesy, Tim F, Yoshimoto, Koji, Nghiemphu, Phioanh, Brown, Kevin, Dang, Julie, Zhu, Shaojun, Hsueh, Teli, Chen, Yinan, Wang, Wei, Youngkin, David, Liau, Linda, Martin, Neil, Becker, Don, Bergsneider, Marvin, Lai, Albert, Green, Richard, Oglesby, Tom, Koleto, Michael, Trent, Jeff, Horvath, Steve, Mischel, Paul S, Mellinghoff, Ingo K, Sawyers, Charles L

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De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients Por Akhavan, David, Pourzia, Alexandra L., Nourian, Alex A., Williams, Kevin J., Nathanson, David, Babic, Ivan, Villa, Genaro R., Tanaka, Kazuhiro, Nael, Ali, Yang, Huijun, Dang, Julie, Vinters, Harry V., Yong, William H., Flagg, Mitchell, Tamanoi, Fuyuhiko, Sasayama, Takashi, James, C. David, Kornblum, Harley I., Cloughesy, Tim F., Cavenee, Webster K., Bensinger, Steven J., Mischel, Paul S.

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Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis Por McGillicuddy, Lauren T., Fromm, Jody A., Hollstein, Pablo E., Kubek, Sara, Beroukhim, Rameen, De Raedt, Thomas, Johnson, Bryan W., Williams, Sybil M.G., Nghiemphu, Phioanh, Liau, Linda, Cloughesy, Tim F., Mischel, Paul S., Parret, Annabel, Seiler, Jeanette, Moldenhauer, Gerd, Scheffzek, Klaus, Stemmer-Rachamimov, Anat O., Sawyers, Charles L., Brennan, Cameron, Messiaen, Ludwine, Mellinghoff, Ingo K., Cichowski, Karen

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Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma Por Singh, Kirit, Batich, Kristen A., Wen, Patrick Y., Tan, Aaron C., Bagley, Stephen J., Lim, Michael, Platten, Michael, Colman, Howard, Ashley, David M., Chang, Susan M., Rahman, Rifaquat, Galanis, Evanthia, Mansouri, Alireza, Puduvalli, Vinay K., Reardon, David A., Sahebjam, Solmaz, Sampson, John H., Simes, John, Berry, Donald A., Zadeh, Gelareh, Cloughesy, Tim F., Mehta, Minesh P., Piantadosi, Steven, Weller, Michael, Heimberger, Amy B., Khasraw, Mustafa

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Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma Por Beroukhim, Rameen, Getz, Gad, Nghiemphu, Leia, Barretina, Jordi, Hsueh, Teli, Linhart, David, Vivanco, Igor, Lee, Jeffrey C., Huang, Julie H., Alexander, Sethu, Du, Jinyan, Kau, Tweeny, Thomas, Roman K., Shah, Kinjal, Soto, Horacio, Perner, Sven, Prensner, John, Debiasi, Ralph M., Demichelis, Francesca, Hatton, Charlie, Rubin, Mark A., Garraway, Levi A., Nelson, Stan F., Liau, Linda, Mischel, Paul S., Cloughesy, Tim F., Meyerson, Matthew, Golub, Todd A., Lander, Eric S., Mellinghoff, Ingo K., Sellers, William R.

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Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain Por Lee, Jeffrey C, Vivanco, Igor, Beroukhim, Rameen, Huang, Julie H. Y, Feng, Whei L, DeBiasi, Ralph M, Yoshimoto, Koji, King, Jennifer C, Nghiemphu, Phioanh, Yuza, Yuki, Xu, Qing, Greulich, Heidi, Thomas, Roman K, Paez, J. Guillermo, Peck, Timothy C, Linhart, David J, Glatt, Karen A, Getz, Gad, Onofrio, Robert, Ziaugra, Liuda, Levine, Ross L, Gabriel, Stacey, Kawaguchi, Tomohiro, O'Neill, Keith, Khan, Haumith, Liau, Linda M, Nelson, Stanley F, Rao, P. Nagesh, Mischel, Paul, Pieper, Russell O, Cloughesy, Tim, Leahy, Daniel J, Sellers, William R, Sawyers, Charles L, Meyerson, Matthew, Mellinghoff, Ingo K

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ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma Por Arrieta, Víctor A., Chen, Andrew X., Kane, J. Robert, Kang, Seong Jae, Kassab, Cynthia, Dmello, Crismita, Zhao, Junfei, Burdett, Kirsten B., Upadhyayula, Pavan, Lee-Chang, Catalina, Shilati, Joseph, Jaishankar, Dinesh, Chen, Li, Gould, Andrew, Zhang, Daniel, Yuan, Jinzhou, Zhao, Wenting, Ling, Xiaoyang, Burks, Jared K., Laffleur, Brice, Amidei, Christina, Bruce, Jeffrey N., Lukas, Rimas V., Yamaguchi, Jonathan T., Cieremans, David, Rothschild, Gerson, Basu, Uttiya, McCord, Matthew, Brat, Daniel J., Zhang, Hui, Cooper, Lee A. D., Zhang, Bin, Sims, Peter, Cloughesy, Tim F., Prins, Robert, Canoll, Peter, Stupp, Roger, Heimberger, Amy B., Horbinski, Craig, Iwamoto, Fabio M., Rabadan, Raul, Sonabend, Adam M.

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