Rezultati - Clemens Scheufler

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  1. 1
    Structure of the Molecular Chaperone Prefoldin

    Structure of the Molecular Chaperone Prefoldin od R. Siegert, Michel R. Leroux, Clemens Scheufler, F.Ulrich Hartl, Ismail Moarefi

    Izdano 2000
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  2. 2
    Structure of TPR Domain–Peptide Complexes

    Structure of TPR Domain–Peptide Complexes od Clemens Scheufler, Achim Brinker, Gleb Bourenkov, Stefano Pegoraro, Luis Moroder, H.D. Bartunik, F. Ulrich Hartl, Ismail Moarefi

    Izdano 2000
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  3. 3
    Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket

    Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket od Clemens Scheufler, Henrik Möbitz, Christoph Gaul, Christian Ragot, C. Be, César Fernández Fernández, Kim S. Beyer, Ralph Tiedt, Frédéric Stauffer

    Izdano 2016
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  4. 4
    Ligand Discrimination by TPR Domains

    Ligand Discrimination by TPR Domains od Achim Brinker, Clemens Scheufler, Florian von der Mülbe, Burkhard Fleckenstein, Christian Herrmann, Günther Jung, Ismail Moarefi, F. Ulrich Hartl

    Izdano 2002
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  5. 5
    Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach

    Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach od Henrik Möbitz, Rainer Machauer, Philipp Holzer, Andrea Vaupel, Frédéric Stauffer, Christian Ragot, Giorgio Caravatti, Clemens Scheufler, César Fernández Fernández, Ulrich Hommel, Ralph Tiedt, Kim S. Beyer, Chao Chen, Hugh Zhu, Christoph Gaul

    Izdano 2017
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  6. 6
    Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach

    Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach od Chao Chen, Hugh Zhu, Frédéric Stauffer, Giorgio Caravatti, Susanne Vollmer, Rainer Machauer, Philipp Holzer, Henrik Möbitz, Clemens Scheufler, Martin Klumpp, Ralph Tiedt, Kim S. Beyer, Keith Calkins, Daniel Guthy, Michael Kiffe, Jeff Zhang, Christoph Gaul

    Izdano 2016
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  7. 7
    Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy

    Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy od Frédéric Morvan, Jean‐Michel Rondeau, Chaochun Zou, Giulia Minetti, Clemens Scheufler, Meike Scharenberg, Carsten Jacobi, Pascale Brebbia, Veronique Ritter, Gauthier Toussaint, Claudia Koelbing, Xavier Charles Leber, Alain Schilb, Florian Witte, Sylvie Lehmann, Elke Koch, Sabine Geisse, David J. Glass, Estelle Lach‐Trifilieff

    Izdano 2017
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  8. 8
    Discovery of selective low molecular weight interleukin-36 receptor antagonists by encoded library technologies

    Discovery of selective low molecular weight interleukin-36 receptor antagonists by encoded library technologies od Juraj Velcicky, Gregor S. Cremosnik, Clemens Scheufler, Peter Meier, Emmanuelle Wirth, Richard Felber, Paul Ramage, Michael Schaefer, Christian Kaiser, Sylvie Lehmann, Raphaela Kutil, Sandra Singeisen, Dorothee Mueller-Ristig, Simone L. Popp, Régis Cèbe, Philipp Lehr, Klemens Kaupmann, P. Erbel, Till A. Röhn, Jérôme Giovannoni, Christoph E. Dumelin, Georg Martiny‐Baron

    Izdano 2025
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  9. 9
    Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent

    Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent od Rita Andraos, Zhiyan Qian, Débora Bonenfant, Joëlle Rubert, Eric Vangrevelinghe, Clemens Scheufler, Fanny Marque, Catherine H. Régnier, Alain De Pover, Hugues Ryckelynck, Neha Bhagwat, Priya Koppikar, Aviva Goel, Lorenza Wyder, Gisele Tavares, Fabienne Baffert, Carole Pissot‐Soldermann, Paul W. Manley, Christoph Gaul, Hans Voshol, Ross L. Levine, William R. Sellers, Francesco Hofmann, Thomas Radimerski

    Izdano 2012
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  10. 10
    Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers

    Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers od Emilie A. Chapeau, Laurent Sansregret, Giorgio Giacomo Galli, Patrick Chêne, Markus Wartmann, Thanos Mourikis, Patricia Jaaks, Sabrina Baltschukat, Inês Amorim Monteiro Barbosa, Daniel Bauer, Saskia M. Brachmann, Clara Delaunay, Claire Estadieu, Jason E. Faris, Pascal Furet, Stefanie Harlfinger, Andreas Hueber, Eloísa Jiménez Núñez, David P. Kodack, Emeline Mandon, Typhaine Martin, Yannick Mesrouze, Vincent Romanet, Clemens Scheufler, Holger Sellner, Christelle Stamm, Dario Sterker, Luca Tordella, Francesco Hofmann, Nicolas Soldermann, Tobias Schmelzle

    Izdano 2024
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  11. 11
    Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers

    Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers od Stéphane Ferretti, Jacques Hamon, Ruben de Kanter, Clemens Scheufler, Rita Andraos-Rey, Stéphanie Barbé, Elisabeth Bechter, Jutta Blank, Vincent Bordas, Ernesta Dammassa, Eric A. Decker, Noemi Di Nanni, Marion Dourdoigne, Elena Gavioli, Marc Hattenberger, Alisa Heuser, Christelle Hemmerlin, Jürgen Hinrichs, Gráinne Kerr, Laurent Laborde, Isabel Jaco, Eloísa Jiménez Núñez, Hans‐Joerg Martus, Cornelia Quadt, Markus Reschke, Vincent Romanet, Fanny Schaeffer, Joseph Schoepfer, Maxime Schrapp, Ross Strang, Hans Voshol, Markus Wartmann, Sarah Welly, Frédéric J. Zécri, Francesco Hofmann, Henrik Möbitz, Marta Cortés-Cros

    Izdano 2024
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  12. 12
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo od Kenji Namoto, Clara Baader, Vanessa Orsini, Alexandro Landshammer, Eva Breuer, Kieu Trinh Dinh, Rosemarie Ungricht, Monika Pikiolek, Stéphane Laurent, Bo Lü, Alexandra Aebi, Katharina Schönberger, Eric Vangrevelinghe, Olivera Evrova, Tianliang Sun, Stefano Annunziato, Julie Lachal, Emily Redmond, Louis Wang, Kristie Wetzel, Paola Capodieci, Jonathan Turner, Gabi Schutzius, Vincent Unterreiner, Markus Trunzer, Nicole Buschmann, Dirk Behnke, Rainer Machauer, Clemens Scheufler, Christian N. Parker, Magali Ferro, Armelle Grevot, Armin Beyerbach, Wei‐Yu Lu, Stuart J. Forbes, Jürgen Wagner, Tewis Bouwmeester, Jun Liu, Bindi Sohal, Sukhdeep K. Sahambi, Linda E. Greenbaum, Felix Lohmann, Philipp S. Hoppe, Feng Cong, Andreas W. Sailer, Heinz Ruffner, Ralf Glatthar, Bostjan Humar, Pierre–Alain Clavien, Michael T. Dill, Elizabeth George, Jürgen Maibaum, Prisca Liberali, Jan S. Tchorz

    Izdano 2024
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