Search Results - Clara Abraham

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  1. 1
    <i>IRF5</i> Risk Polymorphisms Contribute to Interindividual Variance in Pattern Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells

    <i>IRF5</i> Risk Polymorphisms Contribute to Interindividual Variance in Pattern Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells by Matija Hedl, Clara Abraham

    Published 2012
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  2. 2
    Secretory Mediators Regulate Nod2-Induced Tolerance in Human Macrophages

    Secretory Mediators Regulate Nod2-Induced Tolerance in Human Macrophages by Matija Hedl, Clara Abraham

    Published 2010
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  3. 3
    Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

    Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease by Clara Abraham, Ruslan Medzhitov

    Published 2011
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  4. 4
    A <i>TNFSF15</i> disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8–induced IL-1

    A <i>TNFSF15</i> disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8–induced IL-1 by Matija Hedl, Clara Abraham

    Published 2014
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  5. 5
    Activation of Pattern Recognition Receptors Up-Regulates Metallothioneins, Thereby Increasing Intracellular Accumulation of Zinc, Autophagy, and Bacterial Clearance by Macrophages

    Activation of Pattern Recognition Receptors Up-Regulates Metallothioneins, Thereby Increasing Intracellular Accumulation of Zinc, Autophagy, and Bacterial Clearance by Macrophages by Amit Lahiri, Clara Abraham

    Published 2014
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  6. 6
    LFA-1 on CD4+ T Cells Is Required for Optimal Antigen-Dependent Activation In Vivo

    LFA-1 on CD4+ T Cells Is Required for Optimal Antigen-Dependent Activation In Vivo by Sravanthi Kandula, Clara Abraham

    Published 2004
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  7. 7
    Distinct Roles for Nod2 Protein and Autocrine Interleukin-1β in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages

    Distinct Roles for Nod2 Protein and Autocrine Interleukin-1β in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages by Matija Hedl, Clara Abraham

    Published 2011
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  8. 8
    Functional consequences of NOD2 (CARD15) mutations

    Functional consequences of NOD2 (CARD15) mutations by Clara Abraham, Judy H. Cho

    Published 2006
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  9. 9
    Interleukin-23/Th17 pathways and inflammatory bowel disease

    Interleukin-23/Th17 pathways and inflammatory bowel disease by Clara Abraham, Judy H. Cho

    Published 2009
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  10. 10
    Inflammatory Bowel Disease

    Inflammatory Bowel Disease by Clara Abraham, Judy H. Cho

    Published 2009
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  11. 11
    <i>MTMR3</i> risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation

    <i>MTMR3</i> risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation by Amit Lahiri, Matija Hedl, Clara Abraham

    Published 2015
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  12. 12
    The <i>IL18RAP</i> Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling through Innate Receptor–Initiated Pathways

    The <i>IL18RAP</i> Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling through Innate Receptor–Initiated Pathways by Matija Hedl, Shasha Zheng, Clara Abraham

    Published 2014
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  13. 13
    Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses

    Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses by Ritu Sarin, Xingxin Wu, Clara Abraham

    Published 2011
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  14. 14
    IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation

    IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation by Matija Hedl, Jie Yan, Clara Abraham

    Published 2016
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  15. 15
    IL23 induces IL23R recycling and amplifies innate receptor-induced signalling and cytokines in human macrophages, and the IBD-protective IL23R R381Q variant modulates these outcomes

    IL23 induces IL23R recycling and amplifies innate receptor-induced signalling and cytokines in human macrophages, and the IBD-protective IL23R R381Q variant modulates these outcome... by Rui Sun, Matija Hedl, Clara Abraham

    Published 2019
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  16. 16
    Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease

    Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease by Clara Abraham, María T. Abreu, Jerrold R. Turner

    Published 2022
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  17. 17
    Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes

    Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes by Amit Lahiri, Matija Hedl, Jie Yan, Clara Abraham

    Published 2017
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  18. 18
    Chronic stimulation of Nod2 mediates tolerance to bacterial products

    Chronic stimulation of Nod2 mediates tolerance to bacterial products by Matija Hedl, Jing Li, Judy H. Cho, Clara Abraham

    Published 2007
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  19. 19
    CD18 Is Required for Optimal Development and Function of CD4+CD25+ T Regulatory Cells

    CD18 Is Required for Optimal Development and Function of CD4+CD25+ T Regulatory Cells by Marissa Marski, Sravanthi Kandula, Jerrold R. Turner, Clara Abraham

    Published 2005
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  20. 20
    Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases

    Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases by Clara Abraham, Parambir S. Dulai, Séverine Vermeire, William J. Sandborn

    Published 2016
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