תוצאות חיפוש - Cianchetta, Giovanni

Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis מאת Cianchetta, Giovanni, Stouch, Terry, Yu, Wangsheng, Shi, Zhi-Cai, Tari, Leslie W., Swanson, Ronald V., Hunter, Michael J, Hoffman, Isaac D., Liu, Qingyun

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Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation מאת Goodwin, Nicole C., Cianchetta, Giovanni, Burgoon, Hugh A., Healy, Jason, Mabon, Ross, Strobel, Eric D., Allen, Jason, Wang, Shuli, Hamman, Brian D., Rawlins, David B.

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Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase מאת Padyana, Anil K., Gross, Stefan, Jin, Lei, Cianchetta, Giovanni, Narayanaswamy, Rohini, Wang, Feng, Wang, Rui, Fang, Cheng, Lv, Xiaobing, Biller, Scott A., Dang, Lenny, Mahoney, Christopher E., Nagaraja, Nelamangala, Pirman, David, Sui, Zhihua, Popovici-Muller, Janeta, Smolen, Gromoslaw A.

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AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency מאת Kung, Charles, Hixon, Jeff, Kosinski, Penelope A., Cianchetta, Giovanni, Histen, Gavin, Chen, Yue, Hill, Collin, Gross, Stefan, Si, Yaguang, Johnson, Kendall, DeLaBarre, Byron, Luo, Zhiyong, Gu, Zhiwei, Yao, Gui, Tang, Huachun, Fang, Cheng, Xu, Yingxia, Lv, Xiaobing, Biller, Scott, Su, Shin-San Michael, Yang, Hua, Popovici-Muller, Janeta, Salituro, Francesco, Silverman, Lee, Dang, Lenny

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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition מאת Mahoney, Christopher E., Pirman, David, Chubukov, Victor, Sleger, Taryn, Hayes, Sebastian, Fan, Zi Peng, Allen, Eric L., Chen, Ying, Huang, Lingling, Liu, Meina, Zhang, Yingjia, McDonald, Gabrielle, Narayanaswamy, Rohini, Choe, Sung, Chen, Yue, Gross, Stefan, Cianchetta, Giovanni, Padyana, Anil K., Murray, Stuart, Liu, Wei, Marks, Kevin M., Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Nagaraja, Nelamangala, Biller, Scott A., Roddy, Thomas, Popovici-Muller, Janeta, Smolen, Gromoslaw A.

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Recurrent Germline DLST Mutations in Individuals with Multiple Pheochromocytomas and Paragangliomas מאת Remacha, Laura, Pirman, David, Mahoney, Christopher E., Coloma, Javier, Calsina, Bruna, Currás-Freixes, Maria, Letón, Rocío, Torres-Pérez, Rafael, Richter, Susan, Pita, Guillermo, Herráez, Belén, Cianchetta, Giovanni, Honrado, Emiliano, Maestre, Lorena, Urioste, Miguel, Aller, Javier, García-Uriarte, Óscar, Gálvez, María Ángeles, Luque, Raúl M., Lahera, Marcos, Moreno-Rengel, Cristina, Eisenhofer, Graeme, Montero-Conde, Cristina, Rodríguez-Antona, Cristina, Llorca, Óscar, Smolen, Gromoslaw A., Robledo, Mercedes, Cascón, Alberto

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Recurrent Germline DLST Mutations in Individuals with Multiple Pheochromocytomas and Paragangliomas מאת Remacha, Laura, Pirman, David, Mahoney, Christopher E., Coloma, Javier, Calsina, Bruna, Currás-Freixes, Maria, Letón, Rocío, Torres-Pérez, Rafael, Richter, Susan, Pita, Guillermo, Herráez, Belén, Cianchetta, Giovanni, Honrado, Emiliano, Maestre, Lorena, Urioste, Miguel, Aller, Javier, García-Uriarte, Óscar, Gálvez, María Ángeles, Luque, Raúl M., Lahera, Marcos, Moreno-Rengel, Cristina, Eisenhofer, Graeme, Montero-Conde, Cristina, Rodríguez-Antona, Cristina, Llorca, Óscar, Smolen, Gromoslaw A., Robledo, Mercedes, Cascón, Alberto

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Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy מאת Kung, Charles, Hixon, Jeff, Choe, Sung, Marks, Kevin, Gross, Stefan, Murphy, Erin, DeLaBarre, Byron, Cianchetta, Giovanni, Sethumadhavan, Shalini, Wang, Xiling, Yan, Shunqi, Gao, Yi, Fang, Cheng, Wei, Wentao, Jiang, Fan, Wang, Shaohui, Qian, Kevin, Saunders, Jeff, Driggers, Ed, Woo, Hin Koon, Kunii, Kaiko, Murray, Stuart, Yang, Hua, Yen, Katharine, Liu, Wei, Cantley, Lewis C., Vander Heiden, Matthew G., Su, Shinsan M., Jin, Shengfang, Salituro, Francesco G., Dang, Lenny

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Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers מאת Popovici-Muller, Janeta, Lemieux, René M., Artin, Erin, Saunders, Jeffrey O., Salituro, Francesco G., Travins, Jeremy, Cianchetta, Giovanni, Cai, Zhenwei, Zhou, Ding, Cui, Dawei, Chen, Ping, Straley, Kimberly, Tobin, Erica, Wang, Fang, David, Muriel D., Penard-Lacronique, Virginie, Quivoron, Cyril, Saada, Véronique, de Botton, Stéphane, Gross, Stefan, Dang, Lenny, Yang, Hua, Utley, Luke, Chen, Yue, Kim, Hyeryun, Jin, Shengfang, Gu, Zhiwei, Yao, Gui, Luo, Zhiyong, Lv, Xiaobing, Fang, Cheng, Yan, Liping, Olaharski, Andrew, Silverman, Lee, Biller, Scott, Su, Shin-San M., Yen, Katharine

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