Search Results - Chul‐Hwan Lee

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  1. 1
    Chromatin Remodelers Fine-Tune H3K36me-Directed Deacetylation of Neighbor Nucleosomes by Rpd3S

    Chromatin Remodelers Fine-Tune H3K36me-Directed Deacetylation of Neighbor Nucleosomes by Rpd3S by Chul‐Hwan Lee, Jun Wu, Bing Li

    Published 2013
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  2. 2
    Nucleosome Contact Triggers Conformational Changes of Rpd3S Driving High-Affinity H3K36me Nucleosome Engagement

    Nucleosome Contact Triggers Conformational Changes of Rpd3S Driving High-Affinity H3K36me Nucleosome Engagement by Chun Ruan, Chul‐Hwan Lee, Haochen Cui, Sheng Li, Bing Li

    Published 2015
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  3. 3
    PRC2 is high maintenance

    PRC2 is high maintenance by Jia-Ray Yu, Chul‐Hwan Lee, Ozgur Oksuz, James M. Stafford, Danny Reinberg

    Published 2019
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  4. 4
    The role of EZH1 and EZH2 in development and cancer

    The role of EZH1 and EZH2 in development and cancer by Soo Hyun Lee, Yingying Li, Hanbyeol Kim, Seounghyun Eum, Kyumin Park, Chul‐Hwan Lee

    Published 2022
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  5. 5
    Multivalent di-nucleosome recognition enables the Rpd3S histone deacetylase complex to tolerate decreased H3K36 methylation levels

    Multivalent di-nucleosome recognition enables the Rpd3S histone deacetylase complex to tolerate decreased H3K36 methylation levels by Jae‐Wan Huh, Jun Wu, Chul‐Hwan Lee, Miyong Yun, Daniel Gilada, Chad A. Brautigam, Bing Li

    Published 2012
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  6. 6
    Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

    Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin by Chul‐Hwan Lee, Jia-Ray Yu, Sunil Kumar, Ying Jin, Gary LeRoy, Natarajan V. Bhanu, Syuzo Kaneko, Benjamin A. Garcia, Andrew D. Hamilton, Danny Reinberg

    Published 2018
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  7. 7
    LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells

    LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells by Gary LeRoy, Ozgur Oksuz, Nicolas Descostes, Yuki Aoi, Rais A. Ganai, Havva Ortabozkoyun, Jia-Ray Yu, Chul‐Hwan Lee, James M. Stafford, Ali Shilatifard, Danny Reinberg

    Published 2019
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  8. 8
    Epithelial−mesenchymal transition induced by tumor cell-intrinsic PD-L1 signaling predicts a poor response to immune checkpoint inhibitors in PD-L1-high lung cancer

    Epithelial−mesenchymal transition induced by tumor cell-intrinsic PD-L1 signaling predicts a poor response to immune checkpoint inhibitors in PD-L1-high lung cancer by Hyein Jeong, Jaemoon Koh, Sehui Kim, Seung Geun Song, Soo Hyun Lee, Young Joo Jeon, Chul‐Hwan Lee, Bhumsuk Keam, Se‐Hoon Lee, Doo Hyun Chung, Yoon Kyung Jeon

    Published 2024
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  9. 9
    Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction

    Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction by Daniel Grau, Yixiao Zhang, Chul‐Hwan Lee, Marco Igor Valencia‐Sánchez, Jenny Zhang, Miao Wang, Marlene Holder, Vladimir Svetlov, Dongyan Tan, Evgeny Nudler, Danny Reinberg, Thomas Walz, Karim‐Jean Armache

    Published 2021
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  10. 10
    Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2

    Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2 by Chul‐Hwan Lee, Marlene Holder, Daniel Grau, Ricardo Saldaña-Meyer, Jia-Ray Yu, Rais A. Ganai, Jenny Zhang, Miao Wang, Gary LeRoy, Marc‐Werner Dobenecker, Danny Reinberg, Karim‐Jean Armache

    Published 2018
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  11. 11
    Capturing the Onset of PRC2-Mediated Repressive Domain Formation

    Capturing the Onset of PRC2-Mediated Repressive Domain Formation by Ozgur Oksuz, Varun Narendra, Chul‐Hwan Lee, Nicolas Descostes, Gary LeRoy, Ramya Raviram, Lili M. Blumenberg, Kelly R. Karch, Pedro P. Rocha, Benjamin A. García, Jane A. Skok, Danny Reinberg

    Published 2018
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  12. 12
    Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma

    Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma by Chul‐Hwan Lee, Jia-Ray Yu, Jeffrey Granat, Ricardo Saldaña-Meyer, Joshua Andrade, Gary LeRoy, Ying Jin, Peder J. Lund, James M. Stafford, Benjamin A. García, Beatrix Ueberheide, Danny Reinberg

    Published 2019
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  13. 13
    Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer

    Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer by Hyein Jeong, Jaemoon Koh, Sehui Kim, Jeemin Yim, Seung Geun Song, Hanbyeol Kim, Yingying Li, Soo Hyun Lee, Young Keun Chung, Hyun-Seok Kim, Chul‐Hwan Lee, Hye Young Kim, Bhumsuk Keam, Se‐Hoon Lee, Doo Hyun Chung, Yoon Kyung Jeon

    Published 2025
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  14. 14
    Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma

    Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma by James M. Stafford, Chul‐Hwan Lee, Philipp Voigt, Nicolas Descostes, Ricardo Saldaña-Meyer, Jia-Ray Yu, Gary LeRoy, Ozgur Oksuz, Jessica R. Chapman, Fernando Suarez, Aram S. Modrek, N. Sumru Bayın, Dimitris G. Placantonakis, Matthias A. Karajannis, Matija Snuderl, Beatrix Ueberheide, Danny Reinberg

    Published 2018
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  15. 15
    H1 histones control the epigenetic landscape by local chromatin compaction

    H1 histones control the epigenetic landscape by local chromatin compaction by Michael A. Willcockson, Sean E. Healton, Cary N. Weiss, Boris Bartholdy, Yaïr Botbol, Laxmi Mishra, Dhruv S. Sidhwani, Tommy J. Wilson, Hugo Pinto, Maxim I. Maron, Karin A. Skalina, Laura Toro, Jie Zhao, Chul‐Hwan Lee, Harry Hou, Nevin Yusufova, Cem Meydan, Adewola Osunsade, Yael David, Ethel Cesarman, Ari Melnick, Simone Sidoli, Benjamin A. García, Winfried Edelmann, Fernando Macián, Arthur I. Skoultchi

    Published 2020
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