Výsledky vyhledávání - Christopher J. Nirschl

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  1. 1
    Molecular Pathways: Coexpression of Immune Checkpoint Molecules: Signaling Pathways and Implications for Cancer Immunotherapy

    Molecular Pathways: Coexpression of Immune Checkpoint Molecules: Signaling Pathways and Implications for Cancer Immunotherapy Autor Christopher J. Nirschl, Charles G. Drake

    Vydáno 2013
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    Revisão
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  2. 2
    Lymphocyte Activation Gene 3 (LAG-3) Modulates the Ability of CD4 T-cells to Be Suppressed In Vivo

    Lymphocyte Activation Gene 3 (LAG-3) Modulates the Ability of CD4 T-cells to Be Suppressed In Vivo Autor Nicholas M. Durham, Christopher J. Nirschl, Christopher M. Jackson, Jimmy Elias, Christina M. Kochel, Robert A. Anders, Charles G. Drake

    Vydáno 2014
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  3. 3
    Sustained CD4<sup>+</sup>T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide

    Sustained CD4<sup>+</sup>T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide Autor Susannah G. Ellsworth, Ani Sarkis Balmanoukian, Ferdynand Kos, Christopher J. Nirschl, Thomas R. Nirschl, Stuart A. Grossman, Leo Luznik, Charles G. Drake

    Vydáno 2014
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    Artigo
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  4. 4
    Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen

    Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen Autor Andrew B. Sharabi, Christopher J. Nirschl, Christina M. Kochel, Thomas R. Nirschl, Brian J. Francica, Esteban Velarde, Theodore L. DeWeese, Charles G. Drake

    Vydáno 2014
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  5. 5
    Phenotypic and Functional Properties of Helios+ Regulatory T Cells

    Phenotypic and Functional Properties of Helios+ Regulatory T Cells Autor Daniel J. Zabransky, Christopher J. Nirschl, Nicholas M. Durham, Ben V. Park, Christina Ceccato, Tullia C. Bruno, Ada Tam, Derese Getnet, Charles G. Drake

    Vydáno 2012
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  6. 6
    Discovery of a Conditionally Activated IL-2 that Promotes Antitumor Immunity and Induces Tumor Regression

    Discovery of a Conditionally Activated IL-2 that Promotes Antitumor Immunity and Induces Tumor Regression Autor Christopher J. Nirschl, Heather R. Brodkin, Daniel J. Hicklin, Nesreen Ismail, Kristin Morris, Cynthia Seidel‐Dugan, Philipp Steiner, Zoe Steuert, Jenna M. Sullivan, Ethika Tyagi, William M. Winston, Andrés Salmerón

    Vydáno 2022
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  7. 7
    Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance

    Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance Autor Allison Martin, Thomas R. Nirschl, Christopher J. Nirschl, Brian J. Francica, Christina M. Kochel, Adrie van Bokhoven, Alan K. Meeker, M. Scott Lucia, Robert A. Anders, Angelo M. De Marzo, Charles G. Drake

    Vydáno 2015
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  8. 8
    Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia

    Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia Autor Florencia McAllister, Jennifer M. Bailey, Janivette Alsina, Christopher J. Nirschl, Rajni Sharma, Hongni Fan, Yanique Rattigan, Jeffrey C. Roeser, Rachana H. Lankapalli, Hao Zhang, Elizabeth M. Jaffee, Charles G. Drake, Franck Housseau, Anirban Maitra, Jay K. Kolls, Cynthia L. Sears, Drew M. Pardoll, Steven D. Leach

    Vydáno 2014
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  9. 9
    Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination

    Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination Autor Christopher M. Jackson, Christina M. Kochel, Christopher J. Nirschl, Nicholas M. Durham, Jacob Ruzevick, Angela Alme, Brian J. Francica, Jimmy Elias, Andrew Daniels, Thomas W. Dubensky, Peter Lauer, Dirk G. Brockstedt, Emily G. Baxi, Peter A. Calabresi, Janis M. Taube, Carlos A. Pardo, Henry Brem, Drew M. Pardoll, Michael Lim, Charles G. Drake

    Vydáno 2015
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  10. 10
    An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes

    An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes Autor Abhinav Jaiswal, Akanksha Verma, Ruth Dannenfelser, Marit M. Melssen, Itay Tirosh, Benjamin Izar, Tae‐Gyun Kim, Christopher J. Nirschl, K. Sanjana P. Devi, Walter C. Olson, Craig L. Slingluff, Víctor H. Engelhard, Levi A. Garraway, Aviv Regev, Kira Minkis, Charles H. Yoon, Olga G. Troyanskaya, Olivier Elemento, Mayte Suárez‐Fariñas, Niroshana Anandasabapathy

    Vydáno 2022
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  11. 11
    Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

    Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape Autor Seng‐Ryong Woo, Meghan E. Turnis, Monica V. Goldberg, Jaishree Bankoti, Mark Selby, Christopher J. Nirschl, Matthew L. Bettini, David M. Gravano, Peter Vogel, Chih Long Liu, Stephanie Tangsombatvisit, Joseph F. Grosso, George J. Netto, Matthew P. Smeltzer, Alcides Chaux, Paul J. Utz, Creg J. Workman, Drew M. Pardoll, Alan J. Korman, Charles G. Drake, Dario A.A. Vignali

    Vydáno 2011
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  12. 12
    PD-L1 expression in medulloblastoma: an evaluation by subgroup

    PD-L1 expression in medulloblastoma: an evaluation by subgroup Autor Allison Martin, Christopher J. Nirschl, Magda J. Polanczyk, William R. Bell, Thomas R. Nirschl, Sarah Harris‐Bookman, Jillian Phallen, Jessica Hicks, Daniel Martínez, Aleksandra Ogurtsova, Haiying Xu, Lisa Sullivan, Alan K. Meeker, Eric H. Raabe, Kenneth J. Cohen, Charles G. Eberhart, Peter C. Burger, Mariarita Santi, Janis M. Taube, Drew M. Pardoll, Charles G. Drake, Michael Lim

    Vydáno 2018
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  13. 13
    IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

    IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment Autor Christopher J. Nirschl, Mayte Suárez‐Fariñas, Benjamin Izar, Sanjay M. Prakadan, Ruth Dannenfelser, Itay Tirosh, Yong Liu, Qian Zhu, K. Sanjana P. Devi, Shaina L. Carroll, David Chau, Melika Rezaee, Tae‐Gyun Kim, Ruiqi Huang, Judilyn Fuentes‐Duculan, George X. Song‐Zhao, Nicholas Gulati, Michelle A. Lowes, Sandra L. King, Francisco J. Quintana, Young-Suk Lee, James G. Krueger, Kavita Y. Sarin, Charles H. Yoon, Levi A. Garraway, Aviv Regev, Alex K. Shalek, Olga G. Troyanskaya, Niroshana Anandasabapathy

    Vydáno 2017
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