Výsledky vyhledávání - Christopher J. Farady
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Mechanisms of Macromolecular Protease Inhibitors Autor Christopher J. Farady, Charles S. Craik
Vydáno 2010Revisão -
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<scp>GSDMD</scp> membrane pore formation constitutes the mechanism of pyroptotic cell death Autor Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J. Farady, Daniel J. Müller, Petr Brož, Sebastian Hiller
Vydáno 2016Artigo -
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Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm Autor Shivam Rai, Élodie Grockowiak, Nils Hansen, Damien Luque Paz, Cédric B. Stoll, Hui Hao-Shen, Gabriele Mild-Schneider, Stefan Dirnhofer, Christopher J. Farady, Simón Méndez‐Ferrer, Radek C. Skoda
Vydáno 2022Artigo -
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Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design Autor Iain D. Kerr, Ji Hae Lee, Christopher J. Farady, Rachael Marion, Mathias Rickert, Mohammed Sajid, Kailash C. Pandey, Conor R. Caffrey, Jennifer Legac, Elizabeth Hansell, James H. McKerrow, Charles S. Craik, Philip Rosenthal, Linda S. Brinen
Vydáno 2009Artigo -
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IL-1β promotes MPN disease initiation by favoring early clonal expansion of <i>JAK2</i>-mutant hematopoietic stem cells Autor Shivam Rai, Yang Zhang, Élodie Grockowiak, Quentin Kimmerlin, Nils Hansen, Cédric B. Stoll, Marc Usart, Damien Luque Paz, Hui Hao-Shen, Yexuan Zhu, Julien Roux, Michael S. Bader, Stefan Dirnhofer, Christopher J. Farady, Timm Schroeder, Simón Méndez‐Ferrer, Radek C. Skoda
Vydáno 2024Artigo -
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ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157 Autor Dominik Feuerbach, Patrick Schindler, Carmen Barske, Stefanie Joller, Edwige Beng-Louka, Kathleen A. Worringer, Sravya Kommineni, Ajamete Kaykas, Daniel Ho, Chaoyang Ye, Karl Welzenbach, Gaëlle Elain, Laurent Klein, Irena Brzak, Anis K. Mir, Christopher J. Farady, Reiner Aichholz, Simone L. Popp, Nathalie George, Ulf Neumann
Vydáno 2017Artigo -
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Clonal Hematopoiesis of Indeterminate Potential With Loss of <i>Tet2</i> Enhances Risk for Atrial Fibrillation Through <i>Nlrp3</i> Inflammasome Activation Autor Amy Lin, Aneesh Bapat, Ling Xiao, Abhishek Niroula, Jiangchuan Ye, Waihay J. Wong, Mridul Agrawal, Christopher J. Farady, Andreas Boettcher, Christopher A. Hergott, Marie McConkey, Patricio Flores-Bringas, Veronica Shkolnik, Alexander G. Bick, David J. Milan, Pradeep Natarajan, Peter Libby, Patrick T. Ellinor, Benjamin L. Ebert
Vydáno 2024Artigo -
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Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD Autor Brent H. Koehn, Asim Saha, Cameron McDonald-Hyman, Michaël Loschi, Govindarajan Thangavelu, Lie Ma, Michael Zaiken, Josh Dysthe, Walker Krepps, Jamie Panthera, Keli L. Hippen, Stephen C. Jameson, Jeffrey S. Miller, Matthew A. Cooper, Christopher J. Farady, Takao Iwawaki, Jenny P.‐Y. Ting, Jonathan S. Serody, William J. Murphy, Geoffrey R. Hill, Peter J. Murray, Vincenzo Bronte, David H. Munn, Robert Zeiser, Bruce R. Blazar
Vydáno 2019Artigo
Vyhledávací nástroje:
Související témata
Biology
Biochemistry
Cell biology
Immunology
Cancer research
Chemistry
Enzyme
Genetics
Medicine
Haematopoiesis
In vivo
Inflammasome
Inflammation
Protease
Receptor
Stem cell
Apoptosis
Biophysics
Biotechnology
Cancer
Gene
In vitro
Internal medicine
Pathology
Pharmacology
Programmed cell death
Proteases
ADAM10
Active site
Antibody