検索結果 - Christopher J. Farady

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  1. 1
    Mechanisms of Macromolecular Protease Inhibitors

    Mechanisms of Macromolecular Protease Inhibitors 著者: Christopher J. Farady, Charles S. Craik

    出版事項 2010
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    Revisão
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  2. 2
    Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway

    Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway 著者: Ami S. Bhatt, Alana L. Welm, Christopher J. Farady, Maximiliano Vásquez, Keith E. Wilson, Charles S. Craik

    出版事項 2007
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    Artigo
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  3. 3
    Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive <scp>NLRP</scp> 3 inflammasome assembly

    Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive <scp>NLRP</scp> 3 inflammasome assembly 著者: Kaiwen Chen, Benjamin Demarco, Rosalie Heilig, Kateryna Shkarina, Andreas Boettcher, Christopher J. Farady, Paweł Pelczar, Petr Brož

    出版事項 2019
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    Artigo
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  4. 4
    Tumor Detection by Imaging Proteolytic Activity

    Tumor Detection by Imaging Proteolytic Activity 著者: Molly R. Darragh, Eric L. Schneider, Jianlong Lou, Paul Phojanakong, Christopher J. Farady, James D. Marks, Byron Hann, Charles S. Craik

    出版事項 2010
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    Artigo
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  5. 5
    <scp>GSDMD</scp> membrane pore formation constitutes the mechanism of pyroptotic cell death

    <scp>GSDMD</scp> membrane pore formation constitutes the mechanism of pyroptotic cell death 著者: Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J. Farady, Daniel J. Müller, Petr Brož, Sebastian Hiller

    出版事項 2016
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    Artigo
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  6. 6
    Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm

    Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm 著者: Shivam Rai, Élodie Grockowiak, Nils Hansen, Damien Luque Paz, Cédric B. Stoll, Hui Hao-Shen, Gabriele Mild-Schneider, Stefan Dirnhofer, Christopher J. Farady, Simón Méndez‐Ferrer, Radek C. Skoda

    出版事項 2022
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    Artigo
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  7. 7
    Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design

    Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design 著者: Iain D. Kerr, Ji Hae Lee, Christopher J. Farady, Rachael Marion, Mathias Rickert, Mohammed Sajid, Kailash C. Pandey, Conor R. Caffrey, Jennifer Legac, Elizabeth Hansell, James H. McKerrow, Charles S. Craik, Philip Rosenthal, Linda S. Brinen

    出版事項 2009
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    Artigo
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  8. 8
    IL-1β promotes MPN disease initiation by favoring early clonal expansion of <i>JAK2</i>-mutant hematopoietic stem cells

    IL-1β promotes MPN disease initiation by favoring early clonal expansion of <i>JAK2</i>-mutant hematopoietic stem cells 著者: Shivam Rai, Yang Zhang, Élodie Grockowiak, Quentin Kimmerlin, Nils Hansen, Cédric B. Stoll, Marc Usart, Damien Luque Paz, Hui Hao-Shen, Yexuan Zhu, Julien Roux, Michael S. Bader, Stefan Dirnhofer, Christopher J. Farady, Timm Schroeder, Simón Méndez‐Ferrer, Radek C. Skoda

    出版事項 2024
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    Artigo
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  9. 9
    ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157

    ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157 著者: Dominik Feuerbach, Patrick Schindler, Carmen Barske, Stefanie Joller, Edwige Beng-Louka, Kathleen A. Worringer, Sravya Kommineni, Ajamete Kaykas, Daniel Ho, Chaoyang Ye, Karl Welzenbach, Gaëlle Elain, Laurent Klein, Irena Brzak, Anis K. Mir, Christopher J. Farady, Reiner Aichholz, Simone L. Popp, Nathalie George, Ulf Neumann

    出版事項 2017
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    Artigo
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  10. 10
    Clonal Hematopoiesis of Indeterminate Potential With Loss of <i>Tet2</i> Enhances Risk for Atrial Fibrillation Through <i>Nlrp3</i> Inflammasome Activation

    Clonal Hematopoiesis of Indeterminate Potential With Loss of <i>Tet2</i> Enhances Risk for Atrial Fibrillation Through <i>Nlrp3</i> Inflammasome Activation 著者: Amy Lin, Aneesh Bapat, Ling Xiao, Abhishek Niroula, Jiangchuan Ye, Waihay J. Wong, Mridul Agrawal, Christopher J. Farady, Andreas Boettcher, Christopher A. Hergott, Marie McConkey, Patricio Flores-Bringas, Veronica Shkolnik, Alexander G. Bick, David J. Milan, Pradeep Natarajan, Peter Libby, Patrick T. Ellinor, Benjamin L. Ebert

    出版事項 2024
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    Artigo
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  11. 11
    Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

    Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD 著者: Brent H. Koehn, Asim Saha, Cameron McDonald-Hyman, Michaël Loschi, Govindarajan Thangavelu, Lie Ma, Michael Zaiken, Josh Dysthe, Walker Krepps, Jamie Panthera, Keli L. Hippen, Stephen C. Jameson, Jeffrey S. Miller, Matthew A. Cooper, Christopher J. Farady, Takao Iwawaki, Jenny P.‐Y. Ting, Jonathan S. Serody, William J. Murphy, Geoffrey R. Hill, Peter J. Murray, Vincenzo Bronte, David H. Munn, Robert Zeiser, Bruce R. Blazar

    出版事項 2019
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    Artigo
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