Search Results - Christopher Fernández-Prada

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  1. 1
    Cos-Seq for high-throughput identification of drug target and resistance mechanisms in the protozoan parasite <i>Leishmania</i>

    Cos-Seq for high-throughput identification of drug target and resistance mechanisms in the protozoan parasite <i>Leishmania</i> by Élodie Gazanion, Christopher Fernández-Prada, Barbara Papadopoulou, Philippe Leprohon, Marc Ouellette

    Published 2016
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  2. 2
    Unravelling the proteomic signature of extracellular vesicles released by drug-resistant Leishmania infantum parasites

    Unravelling the proteomic signature of extracellular vesicles released by drug-resistant Leishmania infantum parasites by Noélie Douanne, George Dong, Mélanie Douanne, Martin Olivier, Christopher Fernandez‐Prada

    Published 2020
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  3. 3
    Critical loss: the effects of VEuPathDB defunding on global health

    Critical loss: the effects of VEuPathDB defunding on global health by Christopher Fernandez‐Prada, Nilmar Silvio Moretti, Rubens Lima do Monte‐Neto

    Published 2024
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  4. 4
    Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery

    Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery by Arijit Bhattacharya, Audrey Corbeil, Rubens Lima do Monte‐Neto, Christopher Fernández-Prada

    Published 2020
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  5. 5
    Extracellular Vesicles in Trypanosomatids: Host Cell Communication

    Extracellular Vesicles in Trypanosomatids: Host Cell Communication by Ana Claúdia Torrecilhas, Rodrigo Pedro Soares, Sérgio Schenkman, Christopher Fernandez‐Prada, Martin Olivier

    Published 2020
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  6. 6
    Identification of asymptomatic Leishmania infections: a scoping review

    Identification of asymptomatic Leishmania infections: a scoping review by Ana Victoria Ibarra‐Meneses, Audrey Corbeil, Victoria Wagner, Chukwuemeka Onwuchekwa, Christopher Fernandez‐Prada

    Published 2022
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  7. 7
    CRISPR-Cas9 high-throughput screening to study drug resistance in <i>Leishmania infantum</i>

    CRISPR-Cas9 high-throughput screening to study drug resistance in <i>Leishmania infantum</i> by Marine Queffeulou, Philippe Leprohon, Christopher Fernández-Prada, Marc Ouellette, Ana María Mejía‐Jaramillo

    Published 2024
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  8. 8
    Drug resistance analysis by next generation sequencing in Leishmania

    Drug resistance analysis by next generation sequencing in Leishmania by Philippe Leprohon, Christopher Fernandez‐Prada, Élodie Gazanion, Rubens Lima do Monte‐Neto, Marc Ouellette

    Published 2014
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  9. 9
    Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

    Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery by Rafael Balaña‐Fouce, Raquel Álvarez‐Velilla, Christopher Fernández-Prada, Carlos García‐Estrada, Rosa M. Reguera

    Published 2014
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  10. 10
    High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms

    High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms by Christopher Fernández-Prada, Mansi Sharma, Marie Plourde, Eva Bresson, Gaétan Roy, Philippe Leprohon, Marc Ouellette

    Published 2018
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  11. 11
    Leishmania parasites exchange drug-resistance genes through extracellular vesicles

    Leishmania parasites exchange drug-resistance genes through extracellular vesicles by Noélie Douanne, George Dong, Atia Amin, Lorena Bernardo, Mathieu Blanchette, David Langlais, Martin Olivier, Christopher Fernandez‐Prada

    Published 2022
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  12. 12
    Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach

    Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach by Ana Victoria Ibarra‐Meneses, Audrey Corbeil, Victoria Wagner, Francis Beaudry, Rubens Lima do Monte‐Neto, Christopher Fernandez‐Prada

    Published 2022
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  13. 13
    Assessing current and future areas of ecological suitability for Lutzomyia shannoni in North America

    Assessing current and future areas of ecological suitability for Lutzomyia shannoni in North America by Sydney DeWinter, Grace K Nichol, Christopher Fernández-Prada, Amy L. Greer, J. Scott Weese, Katie M. Clow

    Published 2025
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  14. 14
    Three different mutations in the DNA topoisomerase 1B in Leishmania infantum contribute to resistance to antitumor drug topotecan

    Three different mutations in the DNA topoisomerase 1B in Leishmania infantum contribute to resistance to antitumor drug topotecan by Chloé Rosa-Teijeiro, Victoria Wagner, Audrey Corbeil, Ilda D’Annessa, Philippe Leprohon, Rubens Lima do Monte‐Neto, Christopher Fernandez‐Prada

    Published 2021
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  15. 15
    Three Different Mutations in the DNA Topoisomerase 1B in Leishmania Infantum Contribute to Resistance to Antitumor Drug Topotecan

    Three Different Mutations in the DNA Topoisomerase 1B in Leishmania Infantum Contribute to Resistance to Antitumor Drug Topotecan by Chloé Rosa-Teijeiro, Victoria Wagner, Audrey Corbeil, Ilda D’Annessa, Philippe Leprohon, Rubens Lima do Monte‐Neto, Christopher Fernandez‐Prada

    Published 2021
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  16. 16
    Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms

    Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms by Christopher Fernández-Prada, Isabel M. Vincent, Marie‐Christine Brotherton, Matthew H. Roberts, Gaétan Roy, Luís Rivas, Philippe Leprohon, Terry Smith, Marc Ouellette

    Published 2016
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  17. 17
    Indotecan (LMP400) and AM13-55: Two Novel Indenoisoquinolines Show Potential for Treating Visceral Leishmaniasis

    Indotecan (LMP400) and AM13-55: Two Novel Indenoisoquinolines Show Potential for Treating Visceral Leishmaniasis by Rafael Balaña‐Fouce, Christopher Fernández-Prada, José M. Requena, Mark Cushman, Yves Pommier, Raquel Álvarez‐Velilla, José Miguel Escudero-Martínez, Estefanía Calvo‐Álvarez, Yolanda Pérez‐Pertejo, Rosa M. Reguera

    Published 2012
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  18. 18
    Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect

    Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect by Christopher Fernández-Prada, Raquel Álvarez‐Velilla, Rafael Balaña‐Fouce, Carlos Alberto Vanegas Prieto, Estefanía Calvo‐Álvarez, José Miguel Escudero-Martínez, José M. Requena, C. Ordóñez, Alessandro Desideri, Yolanda Pérez‐Pertejo, Rosa M. Reguera

    Published 2013
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  19. 19
    Appraisal of a Leishmania major Strain Stably Expressing mCherry Fluorescent Protein for Both In Vitro and In Vivo Studies of Potential Drugs and Vaccine against Cutaneous Leishmaniasis

    Appraisal of a Leishmania major Strain Stably Expressing mCherry Fluorescent Protein for Both In Vitro and In Vivo Studies of Potential Drugs and Vaccine against Cutaneous Leishman... by Estefanía Calvo‐Álvarez, Néstor Guerrero, Raquel Álvarez‐Velilla, Christopher Fernandez‐Prada, José M. Requena, Carmen Punzón, Miguel Ángel Llamas, Francisco J. Arévalo, Luís Rivas, Manuel Fresno, Yolanda Pérez‐Pertejo, Rafael Balaña‐Fouce, Rosa M. Reguera

    Published 2012
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  20. 20
    Evaluation of the <i>Leishmania</i> Inositol Phosphorylceramide Synthase as a Drug Target Using a Chemical and Genetic Approach

    Evaluation of the <i>Leishmania</i> Inositol Phosphorylceramide Synthase as a Drug Target Using a Chemical and Genetic Approach by Edubiel A. Alpizar-Sosa, Flávia M. Zimbres, Brian S. Mantilla, Emily A. Dickie, Wenbin Wei, Gabriela A. Burle-Caldas, Laura N. S. Filipe, Katrien Van Bocxlaer, Helen P. Price, Ana Victoria Ibarra‐Meneses, Francis Beaudry, Christopher Fernandez‐Prada, Phillip D. Whitfield, Michael P. Barrett, Paul W. Denny

    Published 2024
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