Resultats de la cerca - Christophe Deben

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  1. 1
    STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

    STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy per Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas Van Audenaerde

    Publicat 2025
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  2. 2
    Cellular senescence in cancer: clinical detection and prognostic implications

    Cellular senescence in cancer: clinical detection and prognostic implications per Andreas Domen, Christophe Deben, Jasper Verswyvel, Tal Flieswasser, Hans Prenen, Marc Peeters, Filip Lardon, An Wouters

    Publicat 2022
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  3. 3
    Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

    Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods per Stephanie Jordaens, Karen Zwaenepoel, Wiebren Tjalma, Christophe Deben, Koen Beyers, Vanessa Vankerckhoven, Patrick Pauwels, Alex Vorsters

    Publicat 2023
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  4. 4
    The Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment

    The Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment per Eline Biscop, Abraham Lin, Wilma Van Boxem, Jinthe Van Loenhout, Joey De Backer, Christophe Deben, Sylvia Dewilde, Evelien Smits, Annemie Bogaerts

    Publicat 2019
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  5. 5
    Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

    Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress per Christophe Deben, Vanessa Deschoolmeester, Jorrit De Waele, Julie Jacobs, Jolien Van den Bossche, An Wouters, Marc Peeters, Christian Rolfo, Evelien Smits, Filip Lardon, Patrick Pauwels

    Publicat 2018
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  6. 6
    Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

    Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer per Julie Jacobs, Karen Zwaenepoel, Christian Rolfo, Jolien Van den Bossche, Christophe Deben, Karen Silence, Christophe Hermans, Evelien Smits, Paul Van Schil, Filip Lardon, Vanessa Deschoolmeester, Patrick Pauwels

    Publicat 2015
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  7. 7
    Capturing the Heterogeneity of the PDAC Tumor Microenvironment: Novel Triple Co-Culture Spheroids for Drug Screening and Angiogenic Evaluation

    Capturing the Heterogeneity of the PDAC Tumor Microenvironment: Novel Triple Co-Culture Spheroids for Drug Screening and Angiogenic Evaluation per Ruben Verloy, Angela Privat‐Maldonado, Jonas Van Audenaerde, Sophie Rovers, Hannah Zaryouh, Jorrit De Waele, Delphine Quatannens, Dieter Peeters, Geert Roeyen, Christophe Deben, Evelien Smits, Annemie Bogaerts

    Publicat 2025
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  8. 8
    The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

    The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer per Christophe Deben, An Wouters, Ken Op de Beeck, Jolien Van den Bossche, Julie Jacobs, Karen Zwaenepoel, Marc Peeters, Jan P. van Meerbeeck, Filip Lardon, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels

    Publicat 2015
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  9. 9
    The potential and controversy of targeting STAT family members in cancer

    The potential and controversy of targeting STAT family members in cancer per Yannick Verhoeven, Sam Tilborghs, Julie Jacobs, Jorrit De Waele, Delphine Quatannens, Christophe Deben, Hans Prenen, Patrick Pauwels, Xuan Bich Trinh, An Wouters, Evelien Smits, Filip Lardon, Peter A. van Dam

    Publicat 2019
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  10. 10
    Auranofin Synergizes with the PARP Inhibitor Olaparib to Induce ROS-Mediated Cell Death in Mutant p53 Cancers

    Auranofin Synergizes with the PARP Inhibitor Olaparib to Induce ROS-Mediated Cell Death in Mutant p53 Cancers per Laurie Freire Boullosa, Jinthe Van Loenhout, Tal Flieswasser, Christophe Hermans, Céline Merlin, Ho Wa Lau, Elly Marcq, Marlies Verschuuren, Winnok H. De Vos, Filip Lardon, Evelien Smits, Christophe Deben

    Publicat 2023
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  11. 11
    Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

    Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation per Julie Jacobs, Vanessa Deschoolmeester, Karen Zwaenepoel, Tal Flieswasser, Christophe Deben, Jolien Van den Bossche, Christophe Hermans, Christian Rolfo, Marc Peeters, Olivier De Wever, Filip Lardon, Vasiliki Siozopoulou, Evelien Smits, Patrick Pauwels

    Publicat 2018
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  12. 12
    Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer

    Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer per Andreas Domen, Delphine Quatannens, Sara Zanivan, Christophe Deben, Jonas Van Audenaerde, Evelien Smits, An Wouters, Filip Lardon, Geert Roeyen, Yannick Verhoeven, Annelies Janssens, Timon Vandamme, Peter A. van Dam, Marc Peeters, Hans Prenen

    Publicat 2021
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  13. 13
    Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer

    Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer per Laurie Freire Boullosa, Jinthe Van Loenhout, Tal Flieswasser, Jorrit De Waele, Christophe Hermans, Hilde Lambrechts, Bart Cuypers, Kris Laukens, Esther Bartholomeus, Vasiliki Siozopoulou, Winnok H. De Vos, Marc Peeters, Evelien Smits, Christophe Deben

    Publicat 2021
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  14. 14
    OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening

    OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening per Christophe Deben, Edgar Cardenas De La Hoz, Maxim Le Compte, Paul Van Schil, Jeroen Hendriks, Patrick Lauwers, Suresh Krishan Yogeswaran, Filip Lardon, Patrick Pauwels, Steven Van Laere, Annemie Bogaerts, Evelien Smits, Steve Vanlanduit, Abraham Lin

    Publicat 2022
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  15. 15
    Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer

    Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer per Maxim Le Compte, Edgar Cardenas De La Hoz, Sofía Peeters, Felicia Rodrigues Fortes, Christophe Hermans, Andreas Domen, Evelien Smits, Filip Lardon, Timon Vandamme, Abraham Lin, Steve Vanlanduit, Geert Roeyen, Steven Van Laere, Hans Prenen, Marc Peeters, Christophe Deben

    Publicat 2023
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  16. 16
    Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition

    Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition per Christophe Deben, Laurie Freire Boullosa, Felicia Rodrigues Fortes, Edgar Cardenas De La Hoz, Maxim Le Compte, Sofie Seghers, Marc Peeters, Steve Vanlanduit, Abraham Lin, Krijn K. Dijkstra, Paul Van Schil, Jeroen Hendriks, Hans Prenen, Geert Roeyen, Filip Lardon, Evelien Smits

    Publicat 2024
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  17. 17
    Prognostic implications of cellular senescence in resected non-small cell lung cancer

    Prognostic implications of cellular senescence in resected non-small cell lung cancer per Andreas Domen, Christophe Deben, Ines De Pauw, Christophe Hermans, Hilde Lambrechts, Jasper Verswyvel, Vasiliki Siozopoulou, Patrick Pauwels, Marco Demaria, Mick van de Wiel, Annelies Janssens, Jeroen Hendriks, Paul Van Schil, Jan B. Vermorken, Timon Vandamme, Hans Prenen, Marc Peeters, Filip Lardon, An Wouters

    Publicat 2022
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  18. 18
    IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts

    IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts per Astrid Van den Eynde, Laura Gehrcken, Tias Verhezen, Ho Wa Lau, Christophe Hermans, Hilde Lambrechts, Tal Flieswasser, Delphine Quatannens, Gils Roex, Karen Zwaenepoel, Elly Marcq, Philippe Joye, Edgar Cardenas De La Hoz, Christophe Deben, Alessia Gasparini, Pierre Montay‐Gruel, Maxim Le Compte, Eva Lion, Filip Lardon, Steven Van Laere, Vasiliki Siozopoulou, Diana Campillo-Davó, Jorrit De Waele, Patrick Pauwels, Julie Jacobs, Evelien Smits, Jonas Van Audenaerde

    Publicat 2024
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