Søgeresultater - Christine Tkaczyk

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  1. 1
    NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc RI aggregation

    NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc RI aggregation af Christine Tkaczyk

    Udgivet 2004
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  2. 2
    The Phospholipase Cγ1-dependent Pathway of FcϵRI-mediated Mast Cell Activation Is Regulated Independently of Phosphatidylinositol 3-Kinase

    The Phospholipase Cγ1-dependent Pathway of FcϵRI-mediated Mast Cell Activation Is Regulated Independently of Phosphatidylinositol 3-Kinase af Christine Tkaczyk, Michael A. Beaven, Saskia M. Brachman, Dean D. Metcalfe, Alasdair M. Gilfillan

    Udgivet 2003
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  3. 3
    Kit and FcϵRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells

    Kit and FcϵRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells af Thomas R. Hundley, Alasdair M. Gilfillan, Christine Tkaczyk, Marcus Vinícius Melo de Andrade, Dean D. Metcalfe, Michael A. Beaven

    Udgivet 2004
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  4. 4
    Btk Plays a Crucial Role in the Amplification of FcϵRI-mediated Mast Cell Activation by Kit

    Btk Plays a Crucial Role in the Amplification of FcϵRI-mediated Mast Cell Activation by Kit af Shoko Iwaki, Christine Tkaczyk, Anne B. Satterthwaite, Kristina E. Halcomb, Michael A. Beaven, Dean D. Metcalfe, Alasdair M. Gilfillan

    Udgivet 2005
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  5. 5
    Mechanisms of Neutralization of a Human Anti-α-toxin Antibody

    Mechanisms of Neutralization of a Human Anti-α-toxin Antibody af Vaheh Oganesyan, Li Peng, Melissa Damschroder, Cheng Li, Agnieszka Sadowska, Christine Tkaczyk, Bret R. Sellman, Herren Wu, William F. Dall’Acqua

    Udgivet 2014
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  6. 6
    MEDI4893* Promotes Survival and Extends the Antibiotic Treatment Window in a Staphylococcus aureus Immunocompromised Pneumonia Model

    MEDI4893* Promotes Survival and Extends the Antibiotic Treatment Window in a Staphylococcus aureus Immunocompromised Pneumonia Model af Hua Long, Taylor S. Cohen, Yuru Shi, Vivekananda Datta, Jamese J. Hilliard, Christine Tkaczyk, JoAnn Suzich, C. Kendall Stover, Bret R. Sellman

    Udgivet 2015
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  7. 7
    Candida albicans Augments Staphylococcus aureus Virulence by Engaging the Staphylococcal<i>agr</i>Quorum Sensing System

    Candida albicans Augments Staphylococcus aureus Virulence by Engaging the Staphylococcal<i>agr</i>Quorum Sensing System af Olivia A. Todd, Paul L. Fidel, Janette M. Harro, Jamese J. Hilliard, Christine Tkaczyk, Bret R. Sellman, Mairi C. Noverr, Brian M. Peters

    Udgivet 2019
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  8. 8
    Effects of Linezolid on Suppressing In Vivo Production of Staphylococcal Toxins and Improving Survival Outcomes in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia

    Effects of Linezolid on Suppressing In Vivo Production of Staphylococcal Toxins and Improving Survival Outcomes in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Nec... af Binh An Diep, Anna Afasizheva, Hoan N. Le, Osamu Kajikawa, Gustavo Matute‐Bello, Christine Tkaczyk, Bret R. Sellman, Cédric Badiou, Gérard Lina, Henry F. Chambers

    Udgivet 2013
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  9. 9
    A fungal metabolic regulator underlies infectious synergism during Candida albicans-Staphylococcus aureus intra-abdominal co-infection

    A fungal metabolic regulator underlies infectious synergism during Candida albicans-Staphylococcus aureus intra-abdominal co-infection af Saikat Paul, Olivia A. Todd, Kara R. Eichelberger, Christine Tkaczyk, Bret R. Sellman, Mairi C. Noverr, James E. Cassat, Paul L. Fidel, Brian M. Peters

    Udgivet 2024
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  10. 10
    Identification of Anti-Alpha Toxin Monoclonal Antibodies That Reduce the Severity of Staphylococcus aureus Dermonecrosis and Exhibit a Correlation between Affinity and Potency

    Identification of Anti-Alpha Toxin Monoclonal Antibodies That Reduce the Severity of Staphylococcus aureus Dermonecrosis and Exhibit a Correlation between Affinity and Potency af Christine Tkaczyk, Hua Long, Reena Varkey, Yuru Shi, L. Dettinger, Robert M. Woods, Arnita Barnes, Randall S. MacGill, Susan Wilson, Partha S. Chowdhury, C. Kendall Stover, Bret R. Sellman

    Udgivet 2012
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  11. 11
    Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893

    Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI... af David E. Tabor, Li Yu, Hoyin Mok, Christine Tkaczyk, Bret R. Sellman, Yuling Wu, Vaheh Oganesyan, Tim Slidel, Hasan S. Jafri, Michael McCarthy, Patricia A. Bradford, Mark T. Esser

    Udgivet 2016
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  12. 12
    Staphylococcus aureus Alpha Toxin Suppresses Effective Innate and Adaptive Immune Responses in a Murine Dermonecrosis Model

    Staphylococcus aureus Alpha Toxin Suppresses Effective Innate and Adaptive Immune Responses in a Murine Dermonecrosis Model af Christine Tkaczyk, Melissa Hamilton, Vivekananda Datta, Xiang Ping Yang, Jamese J. Hilliard, Geoffrey L. Stephens, Agnieszka Sadowska, Lei Hua, Terrence O’Day, JoAnn Suzich, C. Kendall Stover, Bret R. Sellman

    Udgivet 2013
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  13. 13
    S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking

    S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking af Taylor S. Cohen, Michelle L. Boland, Brandon B. Boland, Virginia Takahashi, Andrey Tovchigrechko, Young Lee, Aimee D. Wilde, Mark J. Mazaitis, Omari Jones-Nelson, Christine Tkaczyk, Rajiv Raja, C. Kendall Stover, Bret R. Sellman

    Udgivet 2018
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  14. 14
    Anti-Alpha-Toxin Monoclonal Antibody and Antibiotic Combination Therapy Improves Disease Outcome and Accelerates Healing in a Staphylococcus aureus Dermonecrosis Model

    Anti-Alpha-Toxin Monoclonal Antibody and Antibiotic Combination Therapy Improves Disease Outcome and Accelerates Healing in a Staphylococcus aureus Dermonecrosis Model af Jamese J. Hilliard, Vivekananda Datta, Christine Tkaczyk, Melissa Hamilton, Agnieszka Sadowska, Omari Jones-Nelson, Terrence O’Day, Jason Weiss, Szabolcs Szarka, Vien Nguyen, László Prókai, JoAnn Suzich, C. Kendall Stover, Bret R. Sellman

    Udgivet 2014
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  15. 15
    Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus Disease

    Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus Disease af Christine Tkaczyk, Melissa Hamilton, Agnieszka Sadowska, Yuru Shi, Chew-shun Chang, Partha S. Chowdhury, R. Buonapane, Xue Xiao, Paul Warrener, José R. Mediavilla, Barry N. Kreiswirth, JoAnn Suzich, C. Kendall Stover, Bret R. Sellman

    Udgivet 2016
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  16. 16
    Essential role for the p110δ phosphoinositide 3-kinase in the allergic response

    Essential role for the p110δ phosphoinositide 3-kinase in the allergic response af Khaled Ali, Antonio Bilancio, Matthew J. Thomas, Wayne Pearce, Alasdair M. Gilfillan, Christine Tkaczyk, Nicolas Kuehn, Alexander Gray, June Giddings, Emma Peskett, Roy Fox, Ian Bruce, Christoph Walker, Carol Sawyer, Klaus Okkenhaug, Peter M. Finan, Bart Vanhaesebroeck

    Udgivet 2004
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  17. 17
    α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis

    α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis af Bas G. J. Surewaard, Ajitha Thanabalasuriar, Zhutian Zeng, Christine Tkaczyk, Taylor S. Cohen, Bart W. Bardoel, Selina K. Jorch, Carsten Deppermann, Juliane Bubeck Wardenburg, Rachelle P. Davis, Craig N. Jenne, Kendall C. Stover, Bret R. Sellman, Paul Kubes

    Udgivet 2018
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  18. 18
    <i>Staphylococcus aureus</i> α toxin potentiates opportunistic bacterial lung infections

    <i>Staphylococcus aureus</i> α toxin potentiates opportunistic bacterial lung infections af Taylor S. Cohen, Jamese J. Hilliard, Omari Jones-Nelson, Ashley Keller, Terrence O’Day, Christine Tkaczyk, Antonio DiGiandomenico, Melissa Hamilton, Mark Pelletier, Qun Wang, Binh An Diep, Vien T. M. Le, Lily Cheng, JoAnn Suzich, C. Kendall Stover, Bret R. Sellman

    Udgivet 2016
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  19. 19
    Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus aureus-Infected Wounds in Nondiabetic and Diabetic Mice

    Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus aureus-Infected Wounds in Nondiabetic and Diabetic Mice af Roger V. Ortines, Haiyun Liu, Lily Cheng, Taylor S. Cohen, Heather Lawlor, Abhishek Gami, Yu Wang, Carly Dillen, Nathan K. Archer, Robert J. Miller, Alyssa G. Ashbaugh, Bret L. Pinsker, Mark Marchitto, Christine Tkaczyk, C. Kendall Stover, Bret R. Sellman, Lloyd Miller

    Udgivet 2018
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  20. 20
    Mouse model of hematogenous implant-related <i>Staphylococcus aureus</i> biofilm infection reveals therapeutic targets

    Mouse model of hematogenous implant-related <i>Staphylococcus aureus</i> biofilm infection reveals therapeutic targets af Yu Wang, Lily Cheng, David R. Helfer, Alyssa G. Ashbaugh, Robert J. Miller, Alexander J. Tzomides, John M. Thompson, Roger V. Ortines, Andrew Tsai, Haiyun Liu, Carly Dillen, Nathan K. Archer, Taylor S. Cohen, Christine Tkaczyk, C. Kendall Stover, Bret R. Sellman, Lloyd Miller

    Udgivet 2017
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