Ohcanbohtosat - Christine E. Bear

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  1. 1
    A Therapy for Most with Cystic Fibrosis

    A Therapy for Most with Cystic Fibrosis Dahkki Christine E. Bear

    Almmustuhtton 2020
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  2. 2
    Purified Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Does Not Function as an ATP Channel

    Purified Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Does Not Function as an ATP Channel Dahkki Canhui Li, Mohabir Ramjeesingh, Christine E. Bear

    Almmustuhtton 1996
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  3. 3
    Novel method for evaluation of the oligomeric structure of membrane proteins

    Novel method for evaluation of the oligomeric structure of membrane proteins Dahkki Mohabir Ramjeesingh, Ling‐Jun Huan, Elizabeth Garami, Christine E. Bear

    Almmustuhtton 1999
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  4. 4
    Facilitating Structure-Function Studies of CFTR Modulator Sites with Efficiencies in Mutagenesis and Functional Screening

    Facilitating Structure-Function Studies of CFTR Modulator Sites with Efficiencies in Mutagenesis and Functional Screening Dahkki Steven V. Molinski, Saumel Ahmadi, Maurita Hung, Christine E. Bear

    Almmustuhtton 2015
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  5. 5
    Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains

    Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains Dahkki Onofrio Laselva, Steven V. Molinski, Valeria Casavola, Christine E. Bear

    Almmustuhtton 2018
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  6. 6
    Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Potentiator VX-770 (Ivacaftor) Opens the Defective Channel Gate of Mutant CFTR in a Phosphorylation-dependent but ATP-independent Manner

    Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Potentiator VX-770 (Ivacaftor) Opens the Defective Channel Gate of Mutant CFTR in a Phosphorylation-dependent but ATP-ind... Dahkki Paul D. W. Eckford, Canhui Li, Mohabir Ramjeesingh, Christine E. Bear

    Almmustuhtton 2012
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  7. 7
    Anti-Infectives Restore ORKAMBI® Rescue of F508del-CFTR Function in Human Bronchial Epithelial Cells Infected with Clinical Strains of P. aeruginosa

    Anti-Infectives Restore ORKAMBI® Rescue of F508del-CFTR Function in Human Bronchial Epithelial Cells Infected with Clinical Strains of P. aeruginosa Dahkki Onofrio Laselva, Tracy A. Stone, Christine E. Bear, Charles M. Deber

    Almmustuhtton 2020
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  8. 8
    Testing organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs

    Testing organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs Dahkki Abdelkader Daoud, Sunny Xia, Onofrio Laselva, Janet Jiang, Christine E. Bear

    Almmustuhtton 2025
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  9. 9
    Evidence for a Superoxide Permeability Pathway in Endosomal Membranes

    Evidence for a Superoxide Permeability Pathway in Endosomal Membranes Dahkki Davis Mumbengegwi, Qiang Li, Canhui Li, Christine E. Bear, John F. Engelhardt

    Almmustuhtton 2008
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  10. 10
    Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells

    Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells Dahkki Amy P. Wong, Stephanie Chin, Sunny Xia, Jodi Garner, Christine E. Bear, Janet Rossant

    Almmustuhtton 2015
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  11. 11
    Probing Structure-Function Relationships and Gating Mechanisms in the CorA Mg2+ Transport System

    Probing Structure-Function Relationships and Gating Mechanisms in the CorA Mg2+ Transport System Dahkki Jian Payandeh, Canhui Li, Mohabir Ramjeesingh, Ewa Poduch, Christine E. Bear, E.F. Pai

    Almmustuhtton 2008
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  12. 12
    Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene.

    Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene. Dahkki Christine E. Bear, F. Duguay, Angela Naismith, Norbert Kartner, John W. Hanrahan, J.R. Riordan

    Almmustuhtton 1991
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  13. 13
    Functional Rescue of F508del-CFTR Using Small Molecule Correctors

    Functional Rescue of F508del-CFTR Using Small Molecule Correctors Dahkki Steven V. Molinski, Paul D. W. Eckford, Stan Pasyk, Saumel Ahmadi, Stephanie Chin, Christine E. Bear

    Almmustuhtton 2012
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  14. 14
    Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants

    Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants Dahkki Onofrio Laselva, Claire Bartlett, Alec Popa, Hong Ouyang, T. Gunawardena, Tanja Gonska, Theo J. Moraes, Christine E. Bear

    Almmustuhtton 2020
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  15. 15
    Viscoelastic Notch Signaling Hydrogel Induces Liver Bile Duct Organoid Growth and Morphogenesis

    Viscoelastic Notch Signaling Hydrogel Induces Liver Bile Duct Organoid Growth and Morphogenesis Dahkki Muhammad Rizwan, Christopher Ling, Chengyu Guo, Tracy Liu, Jiaxin Jiang, Christine E. Bear, Shinichiro Ogawa, Molly S. Shoichet

    Almmustuhtton 2022
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  16. 16
    The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

    The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected... Dahkki Gergely L. Lukács, X.B. Chang, Christine E. Bear, Norbert Kartner, Asmaa Mohamed, J.R. Riordan, Sergio Grinstein

    Almmustuhtton 1993
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  17. 17
    Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane

    Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane Dahkki Salim T. Islam, Paul D. W. Eckford, Michelle L. Jones, Timothy Nugent, Christine E. Bear, Christian Vogel, Joseph S. Lam

    Almmustuhtton 2013
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  18. 18
    The Chloride Channel ClC-4 Contributes to Endosomal Acidification and Trafficking

    The Chloride Channel ClC-4 Contributes to Endosomal Acidification and Trafficking Dahkki Raha Mohammad-Panah, Rene E. Harrison, Sonja U. Dhani, Cameron Ackerley, Ling‐Jun Huan, Yanchun Wang, Christine E. Bear

    Almmustuhtton 2003
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  19. 19
    Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator

    Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator Dahkki Onofrio Laselva, Claire Bartlett, T. Gunawardena, Hong Ouyang, Paul D. W. Eckford, Theo J. Moraes, Christine E. Bear, Tanja Gonska

    Almmustuhtton 2020
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  20. 20
    Regulation of CFTR expression and function during differentiation of intestinal epithelial cells.

    Regulation of CFTR expression and function during differentiation of intestinal epithelial cells. Dahkki Raman Sood, Christine E. Bear, Wojtek Auerbach, ELSA M. REYES, Timothy J. Jensen, Norbert Kartner, J.R. Riordan, Manuel Buchwald

    Almmustuhtton 1992
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