檢索結果 - Chris de Graaf

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  1. 1
    A Molecular Pharmacologist’s Guide to G Protein–Coupled Receptor Crystallography

    A Molecular Pharmacologist’s Guide to G Protein–Coupled Receptor Crystallography 由 Chayne L. Piscitelli, James Kean, Chris de Graaf, Xavier Deupí

    出版 2015
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  2. 2
    Impact of GPCR Structures on Drug Discovery

    Impact of GPCR Structures on Drug Discovery 由 Miles Congreve, Chris de Graaf, Nigel A. Swain, Christopher G. Tate

    出版 2020
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  3. 3
    Understanding Ligand Binding Selectivity in a Prototypical GPCR Family

    Understanding Ligand Binding Selectivity in a Prototypical GPCR Family 由 Giulio Mattedi, Francesca Deflorian, Jonathan S. Mason, Chris de Graaf, Francesco Luigi Gervasio

    出版 2019
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  4. 4
    Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?

    Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You? 由 Flavio Ballante, Albert J. Kooistra, Stefanie Kampen, Chris de Graaf, Jens Carlsson

    出版 2021
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  5. 5
    Classification Model for the Second Extracellular Loop of Class A GPCRs

    Classification Model for the Second Extracellular Loop of Class A GPCRs 由 Alessandro Nicoli, Andreas Dunkel, Toni Giorgino, Chris de Graaf, Antonella Di Pizio

    出版 2022
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  6. 6
    Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study

    Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study 由 Albert J. Kooistra, Rob Leurs, Iwan J. P. de Esch, Chris de Graaf

    出版 2015
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  7. 7
    A structural chemogenomics analysis of aminergic <scp>GPCRs</scp>: lessons for histamine receptor ligand design

    A structural chemogenomics analysis of aminergic <scp>GPCRs</scp>: lessons for histamine receptor ligand design 由 Albert J. Kooistra, Sebastiaan Kuhne, Iwan J. P. de Esch, Rob Leurs, Chris de Graaf

    出版 2013
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  8. 8
    Advances in therapeutic peptides targeting G protein-coupled receptors

    Advances in therapeutic peptides targeting G protein-coupled receptors 由 Anthony P. Davenport, Conor C. G. Scully, Chris de Graaf, Alastair Brown, Janet J. Maguire

    出版 2020
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  9. 9
    Insights into the structure of class B GPCRs

    Insights into the structure of class B GPCRs 由 Kaspar Hollenstein, Chris de Graaf, Andrea Bortolato, Ming‐Wei Wang, Fiona H. Marshall, Raymond C. Stevens

    出版 2013
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  10. 10
    KLIFS: an overhaul after the first 5 years of supporting kinase research

    KLIFS: an overhaul after the first 5 years of supporting kinase research 由 Georgi K. Kanev, Chris de Graaf, Bart A. Westerman, Iwan J. P. de Esch, Albert J. Kooistra

    出版 2020
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  11. 11
    Structural Analysis of Chemokine Receptor–Ligand Interactions

    Structural Analysis of Chemokine Receptor–Ligand Interactions 由 Marta Arimont, Shan‐Liang Sun, Rob Leurs, Martine J. Smit, Iwan J. P. de Esch, Chris de Graaf

    出版 2017
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  12. 12
    Aminergic GPCR–Ligand Interactions: A Chemical and Structural Map of Receptor Mutation Data

    Aminergic GPCR–Ligand Interactions: A Chemical and Structural Map of Receptor Mutation Data 由 Márton Vass, Sabina Podlewska, Iwan J. P. de Esch, Andrzej J. Bojarski, Rob Leurs, Albert J. Kooistra, Chris de Graaf

    出版 2018
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  13. 13
    Pharmacological modulation of chemokine receptor function

    Pharmacological modulation of chemokine receptor function 由 Danny J. Scholten, Meritxell Canals, David Maussang, Luc Roumen, Martine J. Smit, Maikel Wijtmans, Chris de Graaf, HF Vischer, Rob Leurs

    出版 2011
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  14. 14
    Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands

    Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands 由 Lars Richter, Chris de Graaf, Werner Sieghart, Zdravko Varagić, Martina Mörzinger, Iwan J. P. de Esch, Gerhard F. Ecker, Margot Ernst

    出版 2012
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  15. 15
    Function-specific virtual screening for GPCR ligands using a combined scoring method

    Function-specific virtual screening for GPCR ligands using a combined scoring method 由 Albert J. Kooistra, Henry F. Vischer, Daniel A. McNaught-Flores, Rob Leurs, Iwan J. P. de Esch, Chris de Graaf

    出版 2016
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  16. 16
    Dynamic tuneable G protein-coupled receptor monomer-dimer populations

    Dynamic tuneable G protein-coupled receptor monomer-dimer populations 由 Patricia M. Dijkman, Oliver K. Castell, Alan D. Goddard, Juan C. Muñoz‐García, Chris de Graaf, Mark I. Wallace, Anthony Watts

    出版 2018
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  17. 17
    The Landscape of Atypical and Eukaryotic Protein Kinases

    The Landscape of Atypical and Eukaryotic Protein Kinases 由 Georgi K. Kanev, Chris de Graaf, Iwan J. P. de Esch, Rob Leurs, Thomas Würdinger, Bart A. Westerman, Albert J. Kooistra

    出版 2019
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  18. 18
    Generic GPCR residue numbers – aligning topology maps while minding the gaps

    Generic GPCR residue numbers – aligning topology maps while minding the gaps 由 Vignir Ísberg, Chris de Graaf, Andrea Bortolato, Vadim Cherezov, Vsevolod Katritch, Fiona H. Marshall, Stefan Mordalski, Jean‐Philippe Pin, Raymond C. Stevens, Gerrit Vriend, David E. Gloriam

    出版 2014
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  19. 19
    Discovery of Novel <i>Trypanosoma brucei</i> Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal Structure

    Discovery of Novel <i>Trypanosoma brucei</i> Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal Structure 由 Chimed Jansen, Huanchen Wang, Albert J. Kooistra, Chris de Graaf, Kristina M. Orrling, Hermann Tenor, Thomas Seebeck, David Bailey, Iwan J. P. de Esch, Hengming Ke, Rob Leurs

    出版 2013
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  20. 20
    Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists

    Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists 由 Ali Işbilir, Jan Møller, Marta Arimont, Vladimir Bobkov, Cristina Perpiñá-Viciano, Carsten Hoffmann, Asuka Inoue, Raimond Heukers, Chris de Graaf, Martine J. Smit, Paolo Annibale, Martin J. Lohse

    出版 2020
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