检索结果 - Chris Phillips

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  1. 1
    Cryo-EM: The Resolution Revolution and Drug Discovery

    Cryo-EM: The Resolution Revolution and Drug Discovery 由 Taianá Maia de Oliveira, Lotte van Beek, Fiona Shilliday, J.E. Debreczeni, Chris Phillips

    出版 2020
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    Revisão
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  2. 2
    Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site

    Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site 由 Hongming Chen, Julie A. Tucker, Xiaotao Wang, Paul R. Gavine, Chris Phillips, Martin Augustin, Patrick Schreiner, Stefan Steinbacher, Marian Preston, D. Ogg

    出版 2016
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    Artigo
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  3. 3
    Structural basis of Lewis <sup>b</sup> antigen binding by the <i>Helicobacter pylori</i> adhesin BabA

    Structural basis of Lewis <sup>b</sup> antigen binding by the <i>Helicobacter pylori</i> adhesin BabA 由 Naim Hage, Tina Howard, Chris Phillips, C. Brassington, R. Overman, J.E. Debreczeni, Paul Gellert, Snow Stolnik, G. Sebastiaan Winkler, Franco H. Falcone

    出版 2015
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    Artigo
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  4. 4
    A Dynamic Model of HIV Integrase Inhibition and Drug Resistance

    A Dynamic Model of HIV Integrase Inhibition and Drug Resistance 由 Alex L. Perryman, Stefano Forli, Garrett M. Morris, Catherine Burt, Yuhui Cheng, Michael Palmer, Kevin Whitby, J. Andrew McCammon, Chris Phillips, Arthur J. Olson

    出版 2010
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    Artigo
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  5. 5
    Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1

    Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1 由 Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martín, Charles E. Mowbray, Wendy Panton, Caroline Smith‐Burchnell, Adele Thornberry, H. Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros

    出版 2010
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    Artigo
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  6. 6
    Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase

    Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase 由 Tobias Klein, Navratna Vajpai, Jonathan J. Phillips, Gareth M. Davies, Geoffrey A. Holdgate, Chris Phillips, Julie A. Tucker, Richard A. Norman, Andrew D. Scott, Daniel R. Higazi, David C. Lowe, Gary S. Thompson, Alexander L. Breeze

    出版 2015
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    Artigo
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  7. 7
    Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold

    Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold 由 Roger Castells‐Graells, Kyle Meador, Mark A. Arbing, M.R. Sawaya, Morgan Gee, Duilio Cascio, Emma S. Gleave, J.E. Debreczeni, J. Breed, Karoline Leopold, Ankoor Patel, Dushyant Jahagirdar, Bronwyn Lyons, Sriram Subramaniam, Chris Phillips, Todd O. Yeates

    出版 2023
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    Artigo
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  8. 8
    Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use

    Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use 由 Harshnira Hitesh Patani, Tom D. Bunney, Nethaji Thiyagarajan, Richard A. Norman, D. Ogg, J. Breed, Paul Ashford, Andrew Potterton, Mina Edwards, Sarah V. Williams, Gary S. Thomson, Camilla Pang, Margaret A. Knowles, Alexander L. Breeze, Christine Orengo, Chris Phillips, Matilda Katan

    出版 2016
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    Artigo
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  9. 9
    Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis

    Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis 由 Anna A. Marusiak, Natalie L. Stephenson, Hayeon Baik, Eleanor W. Trotter, Yaoyong Li, Karen Blyth, Susan Mason, Phil Chapman, Lorena A. Puto, Jon Read, C. Brassington, Hannah Pollard, Chris Phillips, Isabelle Green, R. Overman, Matthew Collier, Ewelina Testoni, Crispin Miller, Tony Hunter, Owen J. Sansom, John Brognard

    出版 2015
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    Artigo
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