Rezultati - Chelsea Mayoh

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  1. 1
    Development of siRNA-Loaded Lipid Nanoparticles Targeting Long Non-Coding RNA LINC01257 as a Novel and Safe Therapeutic Approach for t(8;21) Pediatric Acute Myeloid Leukemia

    Development of siRNA-Loaded Lipid Nanoparticles Targeting Long Non-Coding RNA LINC01257 as a Novel and Safe Therapeutic Approach for t(8;21) Pediatric Acute Myeloid Leukemia od Patrick Connerty, Ernest Moles, Charles E. de Bock, Nisitha Jayatilleke, Jenny L. Smith, Soheil Meshinchi, Chelsea Mayoh, Maria Kavallaris, Richard B. Lock

    Izdano 2021
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  2. 2
    Glutamine addiction promotes glucose oxidation in triple-negative breast cancer

    Glutamine addiction promotes glucose oxidation in triple-negative breast cancer od Lake‐Ee Quek, Michelle van Geldermalsen, Yi Fang Guan, Kanu Wahi, Chelsea Mayoh, Seher Balaban, Angel Pang, Qian Wang, Mark J. Cowley, Kristin Brown, Nigel Turner, Andrew J. Hoy, Jeff Holst

    Izdano 2022
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  3. 3
    Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas

    Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas od Aaminah Khan, Laura D. Gamble, Dannielle Upton, Caitlin Ung, Denise Yu, Anahid Ehteda, Ruby Pandher, Chelsea Mayoh, Steven Hébert, Nada Jabado, Claudia L. Kleinman, Mark R. Burns, Murray D. Norris, Michelle Haber, Maria Tsoli, David S. Ziegler

    Izdano 2021
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  4. 4
    Crizotinib and Surgery for Long-Term Disease Control in Children and Adolescents With ALK-Positive Inflammatory Myofibroblastic Tumors

    Crizotinib and Surgery for Long-Term Disease Control in Children and Adolescents With ALK-Positive Inflammatory Myofibroblastic Tumors od Toby N. Trahair, Andrew J. Gifford, Ashleigh M. Fordham, Chelsea Mayoh, Mitali Fadia, Robyn Lukeis, Andrew Wood, Santosh Valvi, Rick Walker, James Blackburn, Erin E. Heyer, Tim R. Mercer, Draga Barbaric, Glenn M. Marshall, Karen L. MacKenzie

    Izdano 2019
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  5. 5
    An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability

    An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability od Zsuzsanna Nagy, Janith A. Seneviratne, Maxwell Kanikevich, William K. Chang, Chelsea Mayoh, Pooja Venkat, Yanhua Du, Cizhong Jiang, Alice Salib, Jessica Koach, Daniel R. Carter, Rituparna Mittra, Tao Liu, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall

    Izdano 2021
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  6. 6
    Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia

    Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia od Klaartje Somers, Angelika Kosciolek, Angelika Bongers, Ali El‐Ayoubi, Mawar Karsa, Chelsea Mayoh, Carol Wadham, Shiloh Middlemiss, Nickolay Neznanov, Ursula R. Kees, Richard B. Lock, Andrei V. Gudkov, Rosemary Sutton, Katerina V. Gurova, Michelle Haber, Murray D. Norris, Michelle J. Henderson

    Izdano 2019
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  7. 7
    Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy

    Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy od Alvin Kamili, Andrew J. Gifford, Nancy Li, Chelsea Mayoh, Shu-Oi Chow, Timothy W. Failes, Georgina L. Eden, Roxanne Cadiz, Jinhan Xie, Robyn Lukeis, Murray D. Norris, Michelle Haber, Geoffrey McCowage, Greg M. Arndt, Toby N. Trahair, Jamie I. Fletcher

    Izdano 2020
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  8. 8
    Network Modeling of microRNA–mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

    Network Modeling of microRNA–mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN od Chi Yan Ooi, Daniel R. Carter, Bing Liu, Chelsea Mayoh, Anneleen Beckers, Amit Lalwani, Zsuzsanna Nagy, Sara De Brouwer, Bieke Decaesteker, Tzong‐Tyng Hung, Murray D. Norris, Michelle Haber, Tao Liu, Katleen De Preter, Frank Speleman, Belamy B. Cheung, Glenn M. Marshall

    Izdano 2018
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  9. 9
    Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

    Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion od Florida Voli, Emanuele Valli, Luigi Lerra, Kathleen Kimpton, Federica Saletta, Federico M. Giorgi, Daniele Mercatelli, Jourdin R.C. Rouaen, Sylvie Shen, Jayne Murray, Aria Ahmed-Cox, Giuseppe Cirillo, Chelsea Mayoh, Paul A. Beavis, Michelle Haber, Joseph A. Trapani, Maria Kavallaris, Orazio Vittorio

    Izdano 2020
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  10. 10
    Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia

    Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia od Marion K. Mateos, Glenn M. Marshall, Pasquale Barbaro, Michael C. Quinn, Carly George, Chelsea Mayoh, Rosemary Sutton, Tamás Révész, Jodie E. Giles, Draga Barbaric, Frank Alvaro, Françoise Méchinaud, Daniel Catchpoole, John A. Lawson, Georgia Chenevix‐Trench, Stuart MacGregor, Rishi S. Kotecha, Luciano Dalla‐Pozza, Toby N. Trahair

    Izdano 2021
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  11. 11
    Targeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia

    Targeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia od Cédric S. Tremblay, Jesslyn Saw, Feng Yan, Jacqueline Boyle, Ovini Amarasinghe, Shokoufeh Abdollahi, Anh Vo, Benjamin J. Shields, Chelsea Mayoh, Hannah McCalmont, Kathryn L. Evans, Anna Steiner, Kevin Parsons, Matthew P. McCormack, David Powell, Nicholas C. Wong, Stephen M. Jane, Richard B. Lock, David J. Curtis

    Izdano 2025
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  12. 12
    Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma

    Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma od David S. Ziegler, Marie Wong, Chelsea Mayoh, Amit Kumar, Maria Tsoli, Emily Mould, Vanessa Tyrrell, Dong‐Anh Khuong‐Quang, Mark Pinese, Velimir Gayevskiy, Richard J. Cohn, Loretta M. S. Lau, Mark Reynolds, Michael C. Cox, Andrew J. Gifford, Michael Rodriguez, Mark J. Cowley, Paul G. Ekert, Glenn M. Marshall, Michelle Haber

    Izdano 2018
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  13. 13
    Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

    Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia od Duohui Jing, Yizhou Huang, Xiaoyun Liu, Keith C.S. Sia, Julia Hlavka-Zhang, Xiaolu Tai, Meng Wang, Cara E. Toscan, Hannah McCalmont, Kathryn Evans, Chelsea Mayoh, Rebecca C. Poulos, Miriam Span, Jian‐Qing Mi, Chao Zhang, Jason W.H. Wong, Dominik Beck, John E. Pimanda, Richard B. Lock

    Izdano 2018
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  14. 14
    OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL

    OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL od Kathryn Evans, Jianxin Duan, Tara Pritchard, Connor Jones, Lisa McDermott, Zhaohui Gu, Cara E. Toscan, Narimanne El-Zein, Chelsea Mayoh, Stephen W. Erickson, Yuelong Guo, Fanying Meng, Donald Jung, Komal S. Rathi, Kathryn G. Roberts, Charles G. Mullighan, Chi‐Sheng Shia, Tillman Pearce, Beverly A. Teicher, Malcolm A. Smith, Richard B. Lock

    Izdano 2019
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  15. 15
    In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

    In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma od Jacqueline Whitehouse, Hilary Hii, Chelsea Mayoh, Marie Wong, Pamela Ajuyah, Paulette Barahona, Louise Cui, Hetal Dholaria, Christine L. White, Molly K. Buntine, Jacob Byrne, Keteryne Rodrigues da Silva, Meegan Howlett, Emily J. Girard, Maria Tsoli, David S. Ziegler, Jason Dyke, Sharon Lee, Paul G. Ekert, Mark J. Cowley, Nicholas G. Gottardo, Raelene Endersby

    Izdano 2023
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  16. 16
    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG od Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M. Giorgi, Jie Liu, Swapna Joshi, Jourdin R.C. Rouaen, Chi Nam Ignatius Pang, Ruby Pandher, Chelsea Mayoh, Yujie Tang, Aaminah Khan, Caitlin Ung, Ornella Tolhurst, Anne Kankean, Elisha Hayden, Rebecca Lehmann, Sylvie Shen, Anjana Gopalakrishnan, Peter Trebilcock, Katerina V. Gurova, Andrei V. Gudkov, Murray D. Norris, Michelle Haber, Orazio Vittorio, Maria Tsoli, David S. Ziegler

    Izdano 2021
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  17. 17
    The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

    The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds od Sujanna Mondal, Pei Y. Liu, Janith A. Seneviratne, Antoine de Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper L.V. Mååg, Jingwei Chen, Matthew Wai Kin Wong, Nenad Bartoniček, Poh Sim Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby N. Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian P. Street, Xu Dong Zhang, G M Marshall, Tao Liu

    Izdano 2025
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  18. 18
    Diagnostic classification of childhood cancer using multiscale transcriptomics

    Diagnostic classification of childhood cancer using multiscale transcriptomics od Federico Comitani, Joshua O. Nash, Sarah Cohen‐Gogo, Astra I. Chang, Timmy T. Wen, Anant Maheshwari, Bipasha Goyal, Earvin S. Tio, Kevin Tabatabaei, Chelsea Mayoh, Regis Zhao, Ben Ho, Ledia Brunga, John E. Lawrence, Petra Balogh, Adrienne M. Flanagan, Sarah A. Teichmann, Annie Huang, Vijay Ramaswamy, Johann Hitzler, Jonathan D. Wasserman, Rebecca Gladdy, Brendan C. Dickson, Uri Tabori, Mark J. Cowley, Sam Behjati, David Malkin, Anita Villani, Meredith S. Irwin, Adam Shlien

    Izdano 2023
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  19. 19
    JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

    JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma od Matthew Wong, Yuting Sun, Zhichao Xi, Giorgio Milazzo, Rebecca C. Poulos, Christoph Bartenhagen, Jessica L. Bell, Chelsea Mayoh, Nicholas Ho, Andrew E. Tee, Xiaoqiong Chen, Yang Li, Roberto Ciaccio, Pei Y. Liu, Chen Chen Jiang, Qing Lan, Nisitha Jayatilleke, Belamy B. Cheung, Michelle Haber, Murray D. Norris, Xu Dong Zhang, Glenn M. Marshall, Jenny Wang, Stefan Hüttelmaier, Matthias Fischer, Jason W.H. Wong, Hong‐Xi Xu, Giovanni Perini, Qihan Dong, Rani E. George, Tao Liu

    Izdano 2019
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  20. 20
    Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

    Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma od Laura D. Gamble, Stefania Purgato, Jayne Murray, Lin Xiao, Denise Yu, Kimberley M. Hanssen, Federico M. Giorgi, Daniel R. Carter, Andrew J. Gifford, Emanuele Valli, Giorgio Milazzo, Alvin Kamili, Chelsea Mayoh, Bing Liu, Georgina L. Eden, Sara Sarraf, Sophie Allan, Simone Di Giacomo, Claudia L. Flemming, Amanda J. Russell, Belamy B. Cheung, André Oberthuer, Wendy B. London, Matthias Fischer, Toby N. Trahair, Jamie I. Fletcher, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Mark R. Burns, Giovanni Perini, Murray D. Norris, Michelle Haber

    Izdano 2019
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