检索结果 - Che‐Leung Law
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Potent Anticarcinoma Activity of the Humanized Anti-CD70 Antibody h1F6 Conjugated to the Tubulin Inhibitor Auristatin via an Uncleavable Linker 由 Ezogelin Oflazoglu, Ivan J. Stone, Kristine A. Gordon, Christopher G. Wood, Elizabeth A. Repasky, Iqbal S. Grewal, Che-Leung Law, Hans-Peter Gerber
出版 2008Artigo -
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Brentuximab Vedotin–Driven Microtubule Disruption Results in Endoplasmic Reticulum Stress Leading to Immunogenic Cell Death and Antitumor Immunity 由 Ryan A. Heiser, Anthony Cao, Weiping Zeng, Michelle Ulrich, Patrick Younan, Martha E. Anderson, Esther S. Trueblood, Mechthild Jonas, Robert Thurman, Che‐Leung Law, Shyra J. Gardai
出版 2023Artigo -
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Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models 由 Li Fu, Kim K. Emmerton, Mechthild Jonas, Xinqun Zhang, Jamie B. Miyamoto, Jocelyn R. Setter, Nicole D. Nicholas, Nicole M. Okeley, Robert P. Lyon, Dennis R. Benjamin, Che‐Leung Law
出版 2016Artigo -
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Preclinical Antilymphoma Activity of a Humanized Anti-CD40 Monoclonal Antibody, SGN-40 由 Che‐Leung Law, Kristine A. Gordon, J.M. Collier, Kerry Klussman, Julie A. McEarchern, Charles G. Cerveny, Bruce Mixan, Wyne P. Lee, Zhonghau Lin, Patricia Valdez, Alan F. Wahl, Iqbal S. Grewal
出版 2005Artigo -
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Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities 由 Julie A. McEarchern, Ezogelin Oflazoglu, Leigh Francisco, Charlotte F. McDonagh, Kristine A. Gordon, Ivan J. Stone, Kerry Klussman, Eileen Turcott, Nico van Rooijen, Paul Carter, Iqbal S. Grewal, Alan F. Wahl, Che‐Leung Law
出版 2006Artigo -
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Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70 由 Julie A. McEarchern, Leia M. Smith, Charlotte F. McDonagh, Kerry Klussman, Kristine A. Gordon, Carol A. Morris-Tilden, Steven Duniho, Maureen C. Ryan, Tamar E. Boursalian, Paul J. Carter, Iqbal S. Grewal, Che‐Leung Law
出版 2008Artigo -
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Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates 由 May S.K. Sutherland, Russell J. Sanderson, Kristine A. Gordon, Jamie B. Andreyka, Charles G. Cerveny, Changpu Yu, Timothy S. Lewis, Damon L. Meyer, Roger F. Zabinski, Svetlana O. Doronina, Peter D. Senter, Che‐Leung Law, Alan F. Wahl
出版 2006Artigo
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Biology
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Monoclonal antibody
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Antibody-drug conjugate
Antibody-dependent cell-mediated cytotoxicity
Antigen