Resultats de la cerca - Charles Spruck

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  1. 1
    Triple‑negative breast cancer therapy: Current and future perspectives (Review)

    Triple‑negative breast cancer therapy: Current and future perspectives (Review) per Kwang‐Ai Won, Charles Spruck

    Publicat 2020
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  2. 2
    Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer

    Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer per Shahab Akhoondi, Linda S. Lindström, Martin Widschwendter, Martin Corcoran, Jonas Bergh, Charles Spruck, Dan Grandér, Olle Sangfelt

    Publicat 2010
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  3. 3
    Cyclin-Dependent Kinase-Associated Proteins Cks1 and Cks2 Are Essential during Early Embryogenesis and for Cell Cycle Progression in Somatic Cells

    Cyclin-Dependent Kinase-Associated Proteins Cks1 and Cks2 Are Essential during Early Embryogenesis and for Cell Cycle Progression in Somatic Cells per Hanna-Stina Martinsson-Ahlzén, Vasco Liberal, Björn Grünenfelder, Susana R. Chaves, Charles Spruck, Steven I. Reed

    Publicat 2008
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  4. 4
    A CDK-Independent Function of Mammalian Cks1

    A CDK-Independent Function of Mammalian Cks1 per Charles Spruck, Heimo Strohmaier, Mark H. Watson, Adrian Smith, Aimee K. Ryan, Wilhelm Krek, Steven I. Reed

    Publicat 2001
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  5. 5
    Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins

    Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins per Vasco Liberal, Hanna-Stina Martinsson-Ahlzén, Jennifer Liberal, Charles Spruck, Martin Widschwendter, Clare H. McGowan, Steven I. Reed

    Publicat 2011
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  6. 6
    Evidence for multiclonality in multicentric Kaposi’s sarcoma

    Evidence for multiclonality in multicentric Kaposi’s sarcoma per Parkash S. Gill, Yvonne Tsai, Adupa P. Rao, Charles Spruck, Tong Zheng, William Harrington, Tony Cheung, Bharat N. Nathwani, Peter A. Jones

    Publicat 1998
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  7. 7
    The Tumor Suppressor Gene <i>hCDC4</i> Is Frequently Mutated in Human T-Cell Acute Lymphoblastic Leukemia with Functional Consequences for Notch Signaling

    The Tumor Suppressor Gene <i>hCDC4</i> Is Frequently Mutated in Human T-Cell Acute Lymphoblastic Leukemia with Functional Consequences for Notch Signaling per Alena Malyukova, Takeaki Dohda, Natalie von der Lehr, Shahab Akhondi, Martin Corcoran, Mats Heyman, Charles Spruck, Dan Grandér, Urban Lendahl, Olle Sangfelt

    Publicat 2007
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  8. 8
    Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase

    Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase per Ajay A. Vashisht, Kimberly B. Zumbrennen, Xinhua Huang, David N. Powers, Armando Durazo, Dahui Sun, Nimesh Bhaskaran, Anja Persson, Mathias Uhlén, Olle Sangfelt, Charles Spruck, Elizabeth A. Leibold, James A. Wohlschlegel

    Publicat 2009
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  9. 9
    SUV39H1 maintains cancer stem cell chromatin state and properties in glioblastoma

    SUV39H1 maintains cancer stem cell chromatin state and properties in glioblastoma per Chunying Li, Qiqi Xie, Sugata Ghosh, Bihui Cao, Yuanning Du, Vo Van Giau, Timothy Y. Huang, Charles Spruck, Richard L. Carpenter, Yanru Wang, Q. Richard Lu, Kenneth P. Nephew, Jia Shen

    Publicat 2025
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  10. 10
    Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

    Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3 per Nathaniel Robichaud, Sonia V. del Rincón, Bonnie Huor, Tommy Alain, Luca A. Petruccelli, Jaclyn Hearnden, Christophe Gonçalves, Stefan Grotegut, Charles Spruck, Luc Furic, Ola Larsson, William J. Muller, Wilson H. Miller, Nahum Sonenberg

    Publicat 2014
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  11. 11
    Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis

    Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis per Ulrich Keller, Jennifer B. Old, Frank C. Dorsey, Jonas A. Nilsson, Lisa M. Nilsson, Kirsteen H. Maclean, Linda H. Chung, Chunying Yang, Charles Spruck, Kelli L. Boyd, Steven I. Reed, John L. Cleveland

    Publicat 2007
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  12. 12
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells per Jia Shen, Zhixin Qiu, Qiulian Wu, Darren Finlay, Guillermina Garcia, Dahui Sun, Juha Rantala, William D. Barshop, Jennifer L. Hope, Ryan C. Gimple, Olle Sangfelt, Linda M. Bradley, James A. Wohlschlegel, Jeremy N. Rich, Charles Spruck

    Publicat 2020
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  13. 13
    FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

    FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma per Aldwin Suryo Rahmanto, Vasil Savov, Andrä Brunner, Sara Bolin, Holger Weishaupt, Alena Malyukova, Gabriela Rosén, Matko Čančer, Sonja Hutter, Anders Sundström, Daisuke Kawauchi, David Jones, Charles Spruck, Michael D. Taylor, Yoon‐Jae Cho, Stefan M. Pfister, Marcel Kool, Andrey Korshunov, Fredrik J. Swartling, Olle Sangfelt

    Publicat 2016
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  14. 14
    <i>FBXW7/hCDC4</i> Is a General Tumor Suppressor in Human Cancer

    <i>FBXW7/hCDC4</i> Is a General Tumor Suppressor in Human Cancer per Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dofou, Christian Marth, Elisabeth Mueller‐Holzner, Martin Corcoran, Markus Dagnell, Sepideh Zabihi Nejad, Babak Noori Nayer, Mohammad Reza Zali, Johan Hansson, Susanne Egyhazi, Fredrik Petersson, Per Sangfelt, Hans Nordgren, Dan Grandér, Steven I. Reed, Martin Widschwendter, Olle Sangfelt, Charles Spruck

    Publicat 2007
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  15. 15
    <scp>CDK</scp>‐mediated activation of the <scp>SCF<sup>FBXO</sup></scp><sup>28</sup> ubiquitin ligase promotes <scp>MYC</scp>‐driven transcription and tumourigenesis and predicts poor survival in breast cancer

    <scp>CDK</scp>‐mediated activation of the <scp>SCF<sup>FBXO</sup></scp><sup>28</sup> ubiquitin ligase promotes <scp>MYC</scp>‐driven transcription and tumourigenesis and predicts p... per Diana Cepeda, Hwee‐Fang Ng, H R Sharifi, Salah Mahmoudi, Vanessa Soto‐Cerrato, Erik Fredlund, Kristina Magnusson, Helén Nilsson, Alena Malyukova, Juha Rantala, Daniel Klevebring, Francesc Viñals, Nimesh Bhaskaran, Siti Mariam Zakaria, Aldwin Suryo Rahmanto, Stefan Grotegut, Michael L. Nielsen, Cristina Al‐Khalili Szigyarto, Dahui Sun, Mikael Lerner, Sanjay Navani, Martin Widschwendter, Mathias Uhlén, Karin Jirström, Fredrik Pontén, James A. Wohlschlegel, Dan Grandér, Charles Spruck, Lars‐Gunnar Larsson, Olle Sangfelt

    Publicat 2013
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  16. 16
    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells

    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells per Zhixin Qiu, Linjie Zhao, Jia Shen, Zhengyu Liang, Qiulian Wu, Kailin Yang, Lihua Min, Ryan C. Gimple, Qiyuan Yang, Shruti Bhargava, Chunyu Jin, Cheryl Kim, Denise Hinz, Deobrat Dixit, Jean Bernatchez, Briana C. Prager, Guoxin Zhang, Zhen Dong, Deguan Lv, Xujun Wang, Leo J.Y. Kim, Zhe Zhu, Katherine A. Jones, Ye Zheng, Xiuxing Wang, Jair L. Siqueira-Neto, Lukas Chávez, Xiang‐Dong Fu, Charles Spruck, Jeremy N. Rich

    Publicat 2022
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