检索结果 - Chang-Xin Shi

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  1. 1
    Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma

    Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma 由 Xiu-Bao Chang, Yuanxiao Zhu, Chang‐Xin Shi, A. Keith Stewart

    出版 2013
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  2. 2
    Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-κB with antimyeloma activity in vitro and in vivo

    Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-κB with antimyeloma activity in vitro and in vivo 由 Rodger E. Tiedemann, Jessica Schmidt, Jonathan J. Keats, Chang-Xin Shi, Yuan Xiao Zhu, Stephen Palmer, Xinliang Mao, Aaron D. Schimmer, A. Keith Stewart

    出版 2008
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  3. 3
    Loss of <i>FAM46C</i> Promotes Cell Survival in Myeloma

    Loss of <i>FAM46C</i> Promotes Cell Survival in Myeloma 由 Yuan Xiao Zhu, Chang-Xin Shi, Laura A. Bruins, Patrick Jedlowski, Xuewei Wang, K. Martin Kortüm, Moulun Luo, Jonathan M. Ahmann, Esteban Braggio, A. Keith Stewart

    出版 2017
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  4. 4
    RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5

    RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5 由 Yuan Xiao Zhu, Rodger E. Tiedemann, Chang-Xin Shi, Holly Yin, Jessica Schmidt, Laura A. Bruins, Jonathan J. Keats, Esteban Braggio, Chris Sereduk, Spyro Mousses, A. Keith Stewart

    出版 2011
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  5. 5
    Multiple myeloma cells’ capacity to decompose H2O2 determines lenalidomide sensitivity

    Multiple myeloma cells’ capacity to decompose H2O2 determines lenalidomide sensitivity 由 Sinto Sebastian, Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, Sonali Panchabhai, Scott A. Van Wier, Greg Ahmann, Marta Chesi, P. Leif Bergsagel, A. Keith Stewart, Rafaël Fonseca

    出版 2016
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  6. 6
    Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival

    Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival 由 Qinqin Xu, Yue-xian Hou, Paul R. Langlais, Patrick Erickson, James Zhu, Chang-Xin Shi, Moulun Luo, Yuanxiao Zhu, Ye Xu, Lawrence J. Mandarino, Keith Stewart, Xiu-Bao Chang

    出版 2016
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  7. 7
    Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity

    Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity 由 Rodger E. Tiedemann, Xinliang Mao, Chang‐Xin Shi, Yuan Xiao Zhu, Stephen Palmer, Michaël Sébag, Ron Marler, Marta Chesi, Rafaël Fonseca, P. Leif Bergsagel, Aaron D. Schimmer, A. Keith Stewart

    出版 2008
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  8. 8
    CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

    CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma 由 Chang-Xin Shi, K. Martin Kortüm, Yuan Xiao Zhu, Laura A. Bruins, Patrick Jedlowski, Patrick G. Votruba, Moulun Luo, Robert A. Stewart, Jonathan M. Ahmann, Esteban Braggio, A. Keith Stewart

    出版 2017
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  9. 9
    Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4

    Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4 由 Yuan Xiao Zhu, Chang-Xin Shi, Laura A. Bruins, Xuewei Wang, Daniel L. Riggs, Brooke Porter, Jonathan M. Ahmann, Cecília Bonolo de Campos, Esteban Braggio, P. Leif Bergsagel, A. Keith Stewart

    出版 2019
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  10. 10
    Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

    Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide 由 Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, Laura A. Bruins, Jessica Schmidt, Scott Van Wier, Xiu-Bao Chang, Chad C. Bjorklund, Rafaël Fonseca, P. Leif Bergsagel, Robert Z. Orlowski, A. Keith Stewart

    出版 2011
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  11. 11
    Extramedullary myeloma whole genome sequencing reveals novel mutations in <scp>C</scp>ereblon, proteasome subunit <scp>G</scp>2 and the glucocorticoid receptor in multi drug resistant disease

    Extramedullary myeloma whole genome sequencing reveals novel mutations in <scp>C</scp>ereblon, proteasome subunit <scp>G</scp>2 and the glucocorticoid receptor in multi drug resist... 由 Jan B. Egan, K. Martin Kortuem, Ahmet Kurdoglu, Tyler Izatt, Jessica Aldrich, Rebecca Reiman, L Taylor Phillips, Angela Baker, Chang‐Xin Shi, Jessica Schmidt, Winnie S. Liang, David W. Craig, John D. Carpten, A. Keith Stewart

    出版 2013
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  12. 12
    Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6

    Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6 由 Rodger E. Tiedemann, Yuan Xiao Zhu, Jessica Schmidt, Hongwei Yin, Chang-Xin Shi, Qiang Que, Gargi D. Basu, David O. Azorsa, Louise M. Perkins, Esteban Braggio, Rafaël Fonseca, P. Leif Bergsagel, Spyro Mousses, A. Keith Stewart

    出版 2009
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  13. 13
    Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides

    Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides 由 Jan B. Egan, Chang-Xin Shi, Waibhav Tembe, Alexis Christoforides, Ahmet Kurdoglu, Shripad Sinari, Sumit Middha, Yan W. Asmann, Jessica Schmidt, Esteban Braggio, Jonathan J. Keats, Rafaël Fonseca, P. Leif Bergsagel, David W. Craig, John D. Carpten, A. Keith Stewart

    出版 2012
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  14. 14
    The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice

    The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice 由 Zubin Zhang, Jiefei Tong, Xiaowen Tang, Jiaxiang Juan, Biyin Cao, Rose Hurren, Guodong Chen, Paul Taylor, Xin Xu, Chang-Xin Shi, Juan Du, Jian Hou, Guanghui Wang, Depei Wu, A. Keith Stewart, Aaron D. Schimmer, Michael F. Moran, Xinliang Mao

    出版 2016
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  15. 15
    Tumor Burden Limits Bispecific Antibody Efficacy through T-cell Exhaustion Averted by Concurrent Cytotoxic Therapy

    Tumor Burden Limits Bispecific Antibody Efficacy through T-cell Exhaustion Averted by Concurrent Cytotoxic Therapy 由 Erin W. Meermeier, Seth J. Welsh, Meaghen E. Sharik, Megan T. Du, Victoria M. Garbitt, Daniel L. Riggs, Chang‐Xin Shi, Caleb K. Stein, Marco Bergsagel, Bryant Chau, Matthew L. Wheeler, Natalie Bezman, Feng Wang, Pavel Strop, P. Leif Bergsagel, Marta Chesi

    出版 2021
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  16. 16
    Combined venetoclax and alvocidib in acute myeloid leukemia

    Combined venetoclax and alvocidib in acute myeloid leukemia 由 James M. Bogenberger, Clifford J. Whatcott, Nanna Hansen, Devora Delman, Chang-Xin Shi, Wontak Kim, Hillary Haws, Katherine K. Soh, Ye Sol Lee, Peter Peterson, Adam Siddiqui-Jain, Steven Weitman, Keith Stewart, David J. Bearss, Ruben A. Mesa, Steven L. Warner, Raoul Tibes

    出版 2017
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  17. 17
    Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma

    Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma 由 Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, K. Martin Kortuem, Laura A. Bruins, Jessica Schmidt, Xiu-Bao Chang, Paul R. Langlais, Moulun Luo, Patrick Jedlowski, Betsy LaPlant, Kristina Laumann, Rafaël Fonseca, P. Leif Bergsagel, Joseph Mıkhael, Martha Q. Lacy, Mia D. Champion, A. Keith Stewart

    出版 2014
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  18. 18
    The clinical significance of cereblon expression in multiple myeloma

    The clinical significance of cereblon expression in multiple myeloma 由 Steven R. Schuster, K. Martin Kortuem, Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, Laura A. Bruins, Jessica Schmidt, Greg Ahmann, Shaji Kumar, S. Vincent Rajkumar, Joseph Mıkhael, Betsy LaPlant, Mia D. Champion, Kristina Laumann, Bart Barlogie, Rafaël Fonseca, P. Leif Bergsagel, Martha Q. Lacy, A. Keith Stewart

    出版 2013
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  19. 19
    IKZF1/3 and CRL4<sup>CRBN</sup> E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

    IKZF1/3 and CRL4<sup>CRBN</sup> E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma 由 Santiago Barrio, Umair Munawar, Yuan Xiao Zhu, Nicola Giesen, Chang-Xin Shi, Matteo C. Da Vià, Ricardo Sánchez, Laura A. Bruins, Theresa Demler, Nicole Müller, Larissa Haertle, Andoni Garitano, Torsten Steinbrunn, Sophia Danhof, Isabel Cuenca, C. Barrio-Garcia, Esteban Braggio, Andreas Rosenwald, Joaquín Martínez‐López, Leo Rasche, Marc S. Raab, A. Keith Stewart, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm

    出版 2019
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  20. 20
    Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma

    Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma 由 Jonathan J. Keats, Rafaël Fonseca, Marta Chesi, Roelandt F.J. Schop, Angela Baker, Wee Joo Chng, Scott Van Wier, Rodger E. Tiedemann, Chang-Xin Shi, Michaël Sébag, Esteban Braggio, Travis Henry, Yuan-Xiao Zhu, Homer Fogle, Tammy Price-Troska, Gregory Ahmann, Catherine Mancini, Leslie A. Brents, Shaji Kumar, Philip R. Greipp, Angela Dispenzieri, Barbara M. Bryant, George Mulligan, Laurakay Bruhn, Michael T. Barrett, Riccardo Valdez, J.M. Trent, A. Keith Stewart, John D. Carpten, P. Leif Bergsagel

    出版 2007
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