Search Results - Chang‐Xin Shi

Refine Results
  1. 1
    Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma

    Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma by Xiu-Bao Chang, Yuanxiao Zhu, Chang‐Xin Shi, A. Keith Stewart

    Published 2013
    Get full text
    Revisão
    Save to List
    Saved in:
  2. 2
    Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-κB with antimyeloma activity in vitro and in vivo

    Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-κB with antimyeloma activity in vitro and in vivo by Rodger E. Tiedemann, Jessica Schmidt, Jonathan J. Keats, Chang-Xin Shi, Yuan Xiao Zhu, Stephen Palmer, Xinliang Mao, Aaron D. Schimmer, A. Keith Stewart

    Published 2008
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  3. 3
    Loss of <i>FAM46C</i> Promotes Cell Survival in Myeloma

    Loss of <i>FAM46C</i> Promotes Cell Survival in Myeloma by Yuan Xiao Zhu, Chang-Xin Shi, Laura A. Bruins, Patrick Jedlowski, Xuewei Wang, K. Martin Kortüm, Moulun Luo, Jonathan M. Ahmann, Esteban Braggio, A. Keith Stewart

    Published 2017
    Get full text
    Artigo
    Save to List
    Saved in:
  4. 4
    RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5

    RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5 by Yuan Xiao Zhu, Rodger E. Tiedemann, Chang-Xin Shi, Holly Yin, Jessica Schmidt, Laura A. Bruins, Jonathan J. Keats, Esteban Braggio, Chris Sereduk, Spyro Mousses, A. Keith Stewart

    Published 2011
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  5. 5
    Multiple myeloma cells’ capacity to decompose H2O2 determines lenalidomide sensitivity

    Multiple myeloma cells’ capacity to decompose H2O2 determines lenalidomide sensitivity by Sinto Sebastian, Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, Sonali Panchabhai, Scott A. Van Wier, Greg Ahmann, Marta Chesi, P. Leif Bergsagel, A. Keith Stewart, Rafaël Fonseca

    Published 2016
    Get full text
    Artigo
    Save to List
    Saved in:
  6. 6
    Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival

    Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival by Qinqin Xu, Yue-xian Hou, Paul R. Langlais, Patrick Erickson, James Zhu, Chang-Xin Shi, Moulun Luo, Yuanxiao Zhu, Ye Xu, Lawrence J. Mandarino, Keith Stewart, Xiu-Bao Chang

    Published 2016
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  7. 7
    Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity

    Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity by Rodger E. Tiedemann, Xinliang Mao, Chang‐Xin Shi, Yuan Xiao Zhu, Stephen Palmer, Michaël Sébag, Ron Marler, Marta Chesi, Rafaël Fonseca, P. Leif Bergsagel, Aaron D. Schimmer, A. Keith Stewart

    Published 2008
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  8. 8
    CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

    CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma by Chang-Xin Shi, K. Martin Kortüm, Yuan Xiao Zhu, Laura A. Bruins, Patrick Jedlowski, Patrick G. Votruba, Moulun Luo, Robert A. Stewart, Jonathan M. Ahmann, Esteban Braggio, A. Keith Stewart

    Published 2017
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  9. 9
    Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4

    Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4 by Yuan Xiao Zhu, Chang-Xin Shi, Laura A. Bruins, Xuewei Wang, Daniel L. Riggs, Brooke Porter, Jonathan M. Ahmann, Cecília Bonolo de Campos, Esteban Braggio, P. Leif Bergsagel, A. Keith Stewart

    Published 2019
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  10. 10
    Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

    Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide by Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, Laura A. Bruins, Jessica Schmidt, Scott Van Wier, Xiu-Bao Chang, Chad C. Bjorklund, Rafaël Fonseca, P. Leif Bergsagel, Robert Z. Orlowski, A. Keith Stewart

    Published 2011
    Get full text
    Artigo
    Save to List
    Saved in:
  11. 11
    Extramedullary myeloma whole genome sequencing reveals novel mutations in <scp>C</scp>ereblon, proteasome subunit <scp>G</scp>2 and the glucocorticoid receptor in multi drug resistant disease

    Extramedullary myeloma whole genome sequencing reveals novel mutations in <scp>C</scp>ereblon, proteasome subunit <scp>G</scp>2 and the glucocorticoid receptor in multi drug resist... by Jan B. Egan, K. Martin Kortuem, Ahmet Kurdoglu, Tyler Izatt, Jessica Aldrich, Rebecca Reiman, L Taylor Phillips, Angela Baker, Chang‐Xin Shi, Jessica Schmidt, Winnie S. Liang, David W. Craig, John D. Carpten, A. Keith Stewart

    Published 2013
    Get full text Get full text
    Carta
    Save to List
    Saved in:
  12. 12
    Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6

    Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6 by Rodger E. Tiedemann, Yuan Xiao Zhu, Jessica Schmidt, Hongwei Yin, Chang-Xin Shi, Qiang Que, Gargi D. Basu, David O. Azorsa, Louise M. Perkins, Esteban Braggio, Rafaël Fonseca, P. Leif Bergsagel, Spyro Mousses, A. Keith Stewart

    Published 2009
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  13. 13
    Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides

    Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides by Jan B. Egan, Chang-Xin Shi, Waibhav Tembe, Alexis Christoforides, Ahmet Kurdoglu, Shripad Sinari, Sumit Middha, Yan W. Asmann, Jessica Schmidt, Esteban Braggio, Jonathan J. Keats, Rafaël Fonseca, P. Leif Bergsagel, David W. Craig, John D. Carpten, A. Keith Stewart

    Published 2012
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  14. 14
    The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice

    The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice by Zubin Zhang, Jiefei Tong, Xiaowen Tang, Jiaxiang Juan, Biyin Cao, Rose Hurren, Guodong Chen, Paul Taylor, Xin Xu, Chang-Xin Shi, Juan Du, Jian Hou, Guanghui Wang, Depei Wu, A. Keith Stewart, Aaron D. Schimmer, Michael F. Moran, Xinliang Mao

    Published 2016
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  15. 15
    Tumor Burden Limits Bispecific Antibody Efficacy through T-cell Exhaustion Averted by Concurrent Cytotoxic Therapy

    Tumor Burden Limits Bispecific Antibody Efficacy through T-cell Exhaustion Averted by Concurrent Cytotoxic Therapy by Erin W. Meermeier, Seth J. Welsh, Meaghen E. Sharik, Megan T. Du, Victoria M. Garbitt, Daniel L. Riggs, Chang‐Xin Shi, Caleb K. Stein, Marco Bergsagel, Bryant Chau, Matthew L. Wheeler, Natalie Bezman, Feng Wang, Pavel Strop, P. Leif Bergsagel, Marta Chesi

    Published 2021
    Get full text
    Artigo
    Save to List
    Saved in:
  16. 16
    Combined venetoclax and alvocidib in acute myeloid leukemia

    Combined venetoclax and alvocidib in acute myeloid leukemia by James M. Bogenberger, Clifford J. Whatcott, Nanna Hansen, Devora Delman, Chang-Xin Shi, Wontak Kim, Hillary Haws, Katherine K. Soh, Ye Sol Lee, Peter Peterson, Adam Siddiqui-Jain, Steven Weitman, Keith Stewart, David J. Bearss, Ruben A. Mesa, Steven L. Warner, Raoul Tibes

    Published 2017
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  17. 17
    Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma

    Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma by Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, K. Martin Kortuem, Laura A. Bruins, Jessica Schmidt, Xiu-Bao Chang, Paul R. Langlais, Moulun Luo, Patrick Jedlowski, Betsy LaPlant, Kristina Laumann, Rafaël Fonseca, P. Leif Bergsagel, Joseph Mıkhael, Martha Q. Lacy, Mia D. Champion, A. Keith Stewart

    Published 2014
    Get full text Get full text
    Artigo
    Save to List
    Saved in:
  18. 18
    The clinical significance of cereblon expression in multiple myeloma

    The clinical significance of cereblon expression in multiple myeloma by Steven R. Schuster, K. Martin Kortuem, Yuan Xiao Zhu, Esteban Braggio, Chang-Xin Shi, Laura A. Bruins, Jessica Schmidt, Greg Ahmann, Shaji Kumar, S. Vincent Rajkumar, Joseph Mıkhael, Betsy LaPlant, Mia D. Champion, Kristina Laumann, Bart Barlogie, Rafaël Fonseca, P. Leif Bergsagel, Martha Q. Lacy, A. Keith Stewart

    Published 2013
    Get full text
    Artigo
    Save to List
    Saved in:
  19. 19
    IKZF1/3 and CRL4<sup>CRBN</sup> E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

    IKZF1/3 and CRL4<sup>CRBN</sup> E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma by Santiago Barrio, Umair Munawar, Yuan Xiao Zhu, Nicola Giesen, Chang-Xin Shi, Matteo C. Da Vià, Ricardo Sánchez, Laura A. Bruins, Theresa Demler, Nicole Müller, Larissa Haertle, Andoni Garitano, Torsten Steinbrunn, Sophia Danhof, Isabel Cuenca, C. Barrio-Garcia, Esteban Braggio, Andreas Rosenwald, Joaquín Martínez‐López, Leo Rasche, Marc S. Raab, A. Keith Stewart, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm

    Published 2019
    Get full text Get full text
    Carta
    Save to List
    Saved in:
  20. 20
    Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma

    Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma by Jonathan J. Keats, Rafaël Fonseca, Marta Chesi, Roelandt F.J. Schop, Angela Baker, Wee Joo Chng, Scott Van Wier, Rodger E. Tiedemann, Chang-Xin Shi, Michaël Sébag, Esteban Braggio, Travis Henry, Yuan-Xiao Zhu, Homer Fogle, Tammy Price-Troska, Gregory Ahmann, Catherine Mancini, Leslie A. Brents, Shaji Kumar, Philip R. Greipp, Angela Dispenzieri, Barbara M. Bryant, George Mulligan, Laurakay Bruhn, Michael T. Barrett, Riccardo Valdez, J.M. Trent, A. Keith Stewart, John D. Carpten, P. Leif Bergsagel

    Published 2007
    Get full text Get full text
    Artigo
    Save to List
    Saved in:

Search Tools: