Search Results - Chaim O. Jacob

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  1. 1
    On the genetics and immunopathogenesis of COVID-19

    On the genetics and immunopathogenesis of COVID-19 by Chaim O. Jacob

    Published 2020
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  2. 2
    Regulation of MHC class II antigen expression. Opposing effects of tumor necrosis factor-alpha on IFN-gamma-induced HLA-DR and Ia expression depends on the maturation and differentiation stage of the cell.

    Regulation of MHC class II antigen expression. Opposing effects of tumor necrosis factor-alpha on IFN-gamma-induced HLA-DR and Ia expression depends on the maturation and different... by Yukiko Watanabe, Chaim O. Jacob

    Published 1991
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  3. 3
    Mutational analysis of TNF-alpha gene reveals a regulatory role for the 3'-untranslated region in the genetic predisposition to lupus-like autoimmune disease.

    Mutational analysis of TNF-alpha gene reveals a regulatory role for the 3'-untranslated region in the genetic predisposition to lupus-like autoimmune disease. by Chaim O. Jacob, S K Lee, Gideon Strassmann

    Published 1996
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  4. 4
    Antibodies against synthetic peptides of the B subunit of cholera toxin: crossreaction and neutralization of the toxin.

    Antibodies against synthetic peptides of the B subunit of cholera toxin: crossreaction and neutralization of the toxin. by Chaim O. Jacob, Michael Sela, Ruth Arnon

    Published 1983
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  5. 5
    Evidence for the involvement of interleukin 6 in experimental cancer cachexia.

    Evidence for the involvement of interleukin 6 in experimental cancer cachexia. by Gideon Strassmann, M Fong, J S Kenney, Chaim O. Jacob

    Published 1992
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  6. 6
    Increased risk of lung cancer in patients with chondromatous hamartoma

    Increased risk of lung cancer in patients with chondromatous hamartoma by Avraham Karasik, Michaela Modan, Chaim O. Jacob, Y Lieberman

    Published 1980
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  7. 7
    Mechanisms of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia.

    Mechanisms of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia. by Gideon Strassmann, Chaim O. Jacob, Rick L. Evans, D Beall, M Fong

    Published 1992
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  8. 8
    In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon.

    In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon. by Chaim O. Jacob, Peter H. van der Meide, Hugh O. McDevitt

    Published 1987
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  9. 9
    Cyclic nucleotide phosphodiesterase type IV participates in the regulation of IL-10 and in the subsequent inhibition of TNF-alpha and IL-6 release by endotoxin-stimulated macrophages.

    Cyclic nucleotide phosphodiesterase type IV participates in the regulation of IL-10 and in the subsequent inhibition of TNF-alpha and IL-6 release by endotoxin-stimulated macrophag... by Taku Kambayashi, Chaim O. Jacob, Dandan Zhou, N. Mazurek, M Fong, Gideon Strassmann

    Published 1995
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  10. 10
    Heterogeneous effects of IFN-gamma in adjuvant arthritis.

    Heterogeneous effects of IFN-gamma in adjuvant arthritis. by Chaim O. Jacob, Joseph Holoshitz, Peter van der Meide, Samuel Strober, Hugh O. McDevitt

    Published 1989
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  11. 11
    Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

    Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. by Chaim O. Jacob, Sadakazu Aiso, Sara A. Michie, H O McDevitt, Hans Acha‐Orbea

    Published 1990
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  12. 12
    Pivotal Role of Stat4 and Stat6 in the Pathogenesis of the Lupus-Like Disease in the New Zealand Mixed 2328 Mice

    Pivotal Role of Stat4 and Stat6 in the Pathogenesis of the Lupus-Like Disease in the New Zealand Mixed 2328 Mice by Chaim O. Jacob, Song Zang, Lily Li, Voicu Ciobanu, Frank Quismorio, Akiei Mizutani, Minoru Satoh, Michael N. Koss

    Published 2003
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  13. 13
    Differential Contribution of IL-4 and STAT6 vs STAT4 to the Development of Lupus Nephritis

    Differential Contribution of IL-4 and STAT6 vs STAT4 to the Development of Lupus Nephritis by Ram Raj Singh, Vijay Saxena, Song Zang, Lily Li, Fred D. Finkelman, David P. Witte, Chaim O. Jacob

    Published 2003
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  14. 14
    Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.

    Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus eryth... by Chaim O. Jacob, Zdenka Fronek, Gail D. Lewis Phillips, M Koo, John A. Hansen, Hugh O. McDevitt

    Published 1990
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  15. 15
    B Cell and BAFF Dependence of IFN-α–Exaggerated Disease in Systemic Lupus Erythematosus-Prone NZM 2328 Mice

    B Cell and BAFF Dependence of IFN-α–Exaggerated Disease in Systemic Lupus Erythematosus-Prone NZM 2328 Mice by Noam Jacob, Shunhua Guo, Alexis Mathian, Michael N. Koss, Simona Gindea, Chaim Putterman, Chaim O. Jacob, William Stohl

    Published 2011
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  16. 16
    Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF

    Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF by Chaim O. Jacob, Luminita Pricop, Chaim Putterman, Michael N. Koss, Yi Liu, Maria Kollaros, Sarah A. Bixler, Christine Ambrose, Martin Scott, William Stohl

    Published 2006
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  17. 17
    Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells

    Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells by Sonya Wolf, Shannon N. Estadt, Jonathan Theros, Tyson Moore, Jason S. Ellis, Jianhua Liu, Tamra J. Reed, Chaim O. Jacob, Jóhann E. Guðjónsson, J. Michelle Kahlenberg

    Published 2019
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  18. 18
    Deficiency of Type I IFN Receptor in Lupus-Prone New Zealand Mixed 2328 Mice Decreases Dendritic Cell Numbers and Activation and Protects from Disease

    Deficiency of Type I IFN Receptor in Lupus-Prone New Zealand Mixed 2328 Mice Decreases Dendritic Cell Numbers and Activation and Protects from Disease by Hemant Agrawal, Noam Jacob, Esther Carreras, Sandra Bajaña, Chaim Putterman, Seán Turner, Barbara R. Neas, Alexis Mathian, Michael N. Koss, William Stohl, Susan Kovats, Chaim O. Jacob

    Published 2009
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  19. 19
    Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-Associated Pathway

    Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-A... by Noam Jacob, Haitao Yang, Luminita Pricop, Yi Liu, Xiaoni Gao, Song Guo Zheng, Juhua Wang, Hua-Xin Gao, Chaim Putterman, Michael N. Koss, William Stohl, Chaim O. Jacob

    Published 2009
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  20. 20
    Genome-Wide Screen for Systemic Lupus Erythematosus Susceptibility Genes in Multiplex Families

    Genome-Wide Screen for Systemic Lupus Erythematosus Susceptibility Genes in Multiplex Families by Ruty Mehrian‐Shai, Francisco P. Quismorio, Lin Li, Oh Joon Kwon, John L. Morrison, Daniel J. Wallace, C. Michael Neuwelt, Chaim Brautbar, W. James Gauderman, Chaim O. Jacob

    Published 1999
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