Canlyniadau Chwilio - Cath Trigwell
- Dangos 1 - 4 canlyniadau o 4
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1
Feedback Suppression of PI3Kα Signaling in PTEN-Mutated Tumors Is Relieved by Selective Inhibition of PI3Kβ gan Sarit Schwartz, John Wongvipat, Cath Trigwell, Urs J. Hancox, Brett S. Carver, Vanessa Rodrik-Outmezguine, Marie Will, Paige Yellen, Elisa de Stanchina, José Baselga, Howard I. Scher, Simon T. Barry, Charles L. Sawyers, Sarat Chandarlapaty, Neal Rosen
Cyhoeddwyd 2014Artigo -
2
AZD8931, an Equipotent, Reversible Inhibitor of Signaling by Epidermal Growth Factor Receptor, ERBB2 (HER2), and ERBB3: A Unique Agent for Simultaneous ERBB Receptor Blockade in Ca... gan D. Mark Hickinson, Teresa Klinowska, Georgina Speake, John P. Vincent, Cath Trigwell, Judith Anderton, Sarah Beck, Gayle Marshall, Sara Davenport, Rowena Callis, Elizabeth Mills, Konstantina Grosios, Paul D. Smith, Bernard Barlaam, Robert W. Wilkinson, Donald Ogilvie
Cyhoeddwyd 2010Artigo -
3
Intermittent High-Dose Scheduling of AZD8835, a Novel Selective Inhibitor of PI3Kα and PI3Kδ, Demonstrates Treatment Strategies for <i>PIK3CA</i>-Dependent Breast Cancers gan Kevin Hudson, Urs J. Hancox, Cath Trigwell, Robert McEwen, Urszula M. Polanska, Myria Nikolaou, Pablo Morentin Gutierrez, Alvaro Avivar‐Valderas, Oona Delpuech, Phillippa Dudley, Lyndsey Hanson, Rebecca Ellston, Alys Jones, Marie Cumberbatch, Sabina Cosulich, Lara Ward, Francisco Cruzalegui, Stephen Green
Cyhoeddwyd 2016Artigo -
4
Inhibition of PI3Kβ Signaling with AZD8186 Inhibits Growth of PTEN-Deficient Breast and Prostate Tumors Alone and in Combination with Docetaxel gan Urs J. Hancox, Sabina Cosulich, Lyndsey Hanson, Cath Trigwell, Carol Lenaghan, Rebecca Ellston, Hannah Dry, Claire Crafter, Bernard Barlaam, Martina Fitzek, Paul D. Smith, Donald Ogilvie, Celina M. D’Cruz, Lillian Castriotta, Stephen R. Wedge, Lara Ward, Steve Powell, Mandy Lawson, Barry R. Davies, Elizabeth A. Harrington, Emily Foster, Marie Cumberbatch, Stephen Green, Simon T. Barry
Cyhoeddwyd 2014Artigo
Offerynnau Chwilio:
Pynciau Perthynol
Cancer research
Medicine
Biochemistry
Biology
Cancer
Cell biology
Chemistry
Internal medicine
PI3K/AKT/mTOR pathway
Signal transduction
Breast cancer
PTEN
Pharmacology
Apoptosis
Cell growth
Docetaxel
Drug
EGFR inhibitors
ERBB3
Epidermal growth factor
Epidermal growth factor receptor
ErbB
Estrogen receptor
Gefitinib
Growth factor receptor
Growth inhibition
Lapatinib
Phosphorylation
Prostate
Prostate cancer